NAPLEX EASY EXAM QUESTIONS AND
CORRECT ANSWERS | LATEST 2025-2026
VERSION
The student pharmacist performed a two-compartment model for dosing
of LR's theophylline. The student predicted the theophylline
concentration to be 10 mg/L; however, after a serum sample was
obtained and analyzed, the theophylline concentration was 25 mg/L.
What parameters could affect theophylline's clearance that would
account for the error in calculation? Select ALL that apply.
A) Smoking history
B) Hepatic cirrhosis
C) Drug interactions (cytochrome P-450 inhibitors especially especially
1A2, 2E1, 3A4)
D) Renal failure - Answer-A, B and C
In what patient(s) may a Haemophilus influenzae type b (Hib) vaccine
be administered? Select ALL that apply.
,A) A 4-month old infant
B) A 20-year-old smoker
C) A 58-year-old man with leukemia
D) A 26-year-old with asplenia - Answer-A, C and D
Which of the following antiretrovirals should be used with caution in
patients with a sulfa allergy? Select ALL that apply.
A) Fosamprenavir
B) Tipranavir
C) Darunavir
D) Indinavir - Answer-A, B and C
CR is a 52-year-old man diagnosed with chronic hepatitis C (HCV)
genotype 1. Today, he will begin peg-interferon alpha-2b and ribavirin
therapy. Which of the following counseling topics is appropriate?
A) CR should use 2 forms of birth control
B) CR's therapy will last 24 weeks
C) CR likely developed HCV from a contaminated food source
D) CR likely acquired HCV from perinatal transmission - Answer-A
,Preparedness is achieved and maintained by which of the following?
Select ALL that apply.
A) Planning
B) Organizing
C) Training
D) Exercising - Answer-A, B, C and D
VT is a 28-year-old man with stage IV metastatic melanoma, who is
receiving biochemotherapy treatment with cisplatin, vinblastine,
dacarbazine, interferon-alfa 2b, and interleukin-2. His laboratory values
prior to treatment are within normal limits. Which of the following is a
supportive care management option for VT's biochemotherapy treatment
that you would recommend? Select ALL that apply.
A) Premedication with acetaminophen
B) Premedication with dolasetron and dexamethasone
C) Premedication with 0.25 mg IV push
D) Premedication with naloxone - Answer-A and B
A patient presents to your pharmacy to ask a question about influenza
symptom resolution. She was diagnosed with influenza B. She still has
cough and malaise. What should you discuss with the patient?
A) Influenza symptoms will disappear within 48 hours. If you are still
having symptoms, see your provider.
, B) Influenza symptoms typically last 3 to 7 days. Cough and malaise
may last up to 2 weeks. If your symptoms have increased/worsened, you
may need to see your provider.
C) Influenza does not cause a cough. The patient should be counseled to
see her provider.
D) As long as a patient does not have a fever, there is no need to worry.
Cough and malaise symptoms will go away. - Answer-B
KZ has developed neutropenia and the oncologist will initiate treatment
to increase the white blood cell count. KZ has a past medical history of
hypertension and diabetes. Medications include lisinopril and
metformin. What are potential options for management of KZ's
neutropenia? Select ALL that apply.
A) Epoetin alfa
B) Granulocyte colony stimulating factor
C) Granulocyte-macrophage colony stimulating factor
D) Dexrazoxane - Answer-B and C
UV is a patient with partial epilepsy being treated with oxcarbazepine.
UV has been stable (seizure free) for 18 months and is tolerating the
medication well. UV is presenting to a triage clinic with complaints of
nausea, vomiting, headache, confusion, lack of energy, fatigue,
restlessness, irritability, muscle cramps, and recent seizure. The
emergency room provider is evaluating possible causes of UV's
symptoms. UV has a past medical history significant for hypertension,
diabetes, dyslipidemia, and partial epilepsy. Medications include
metoprolol tartrate, metformin, pitavastatin, and oxcarbazepine. Family
CORRECT ANSWERS | LATEST 2025-2026
VERSION
The student pharmacist performed a two-compartment model for dosing
of LR's theophylline. The student predicted the theophylline
concentration to be 10 mg/L; however, after a serum sample was
obtained and analyzed, the theophylline concentration was 25 mg/L.
What parameters could affect theophylline's clearance that would
account for the error in calculation? Select ALL that apply.
A) Smoking history
B) Hepatic cirrhosis
C) Drug interactions (cytochrome P-450 inhibitors especially especially
1A2, 2E1, 3A4)
D) Renal failure - Answer-A, B and C
In what patient(s) may a Haemophilus influenzae type b (Hib) vaccine
be administered? Select ALL that apply.
,A) A 4-month old infant
B) A 20-year-old smoker
C) A 58-year-old man with leukemia
D) A 26-year-old with asplenia - Answer-A, C and D
Which of the following antiretrovirals should be used with caution in
patients with a sulfa allergy? Select ALL that apply.
A) Fosamprenavir
B) Tipranavir
C) Darunavir
D) Indinavir - Answer-A, B and C
CR is a 52-year-old man diagnosed with chronic hepatitis C (HCV)
genotype 1. Today, he will begin peg-interferon alpha-2b and ribavirin
therapy. Which of the following counseling topics is appropriate?
A) CR should use 2 forms of birth control
B) CR's therapy will last 24 weeks
C) CR likely developed HCV from a contaminated food source
D) CR likely acquired HCV from perinatal transmission - Answer-A
,Preparedness is achieved and maintained by which of the following?
Select ALL that apply.
A) Planning
B) Organizing
C) Training
D) Exercising - Answer-A, B, C and D
VT is a 28-year-old man with stage IV metastatic melanoma, who is
receiving biochemotherapy treatment with cisplatin, vinblastine,
dacarbazine, interferon-alfa 2b, and interleukin-2. His laboratory values
prior to treatment are within normal limits. Which of the following is a
supportive care management option for VT's biochemotherapy treatment
that you would recommend? Select ALL that apply.
A) Premedication with acetaminophen
B) Premedication with dolasetron and dexamethasone
C) Premedication with 0.25 mg IV push
D) Premedication with naloxone - Answer-A and B
A patient presents to your pharmacy to ask a question about influenza
symptom resolution. She was diagnosed with influenza B. She still has
cough and malaise. What should you discuss with the patient?
A) Influenza symptoms will disappear within 48 hours. If you are still
having symptoms, see your provider.
, B) Influenza symptoms typically last 3 to 7 days. Cough and malaise
may last up to 2 weeks. If your symptoms have increased/worsened, you
may need to see your provider.
C) Influenza does not cause a cough. The patient should be counseled to
see her provider.
D) As long as a patient does not have a fever, there is no need to worry.
Cough and malaise symptoms will go away. - Answer-B
KZ has developed neutropenia and the oncologist will initiate treatment
to increase the white blood cell count. KZ has a past medical history of
hypertension and diabetes. Medications include lisinopril and
metformin. What are potential options for management of KZ's
neutropenia? Select ALL that apply.
A) Epoetin alfa
B) Granulocyte colony stimulating factor
C) Granulocyte-macrophage colony stimulating factor
D) Dexrazoxane - Answer-B and C
UV is a patient with partial epilepsy being treated with oxcarbazepine.
UV has been stable (seizure free) for 18 months and is tolerating the
medication well. UV is presenting to a triage clinic with complaints of
nausea, vomiting, headache, confusion, lack of energy, fatigue,
restlessness, irritability, muscle cramps, and recent seizure. The
emergency room provider is evaluating possible causes of UV's
symptoms. UV has a past medical history significant for hypertension,
diabetes, dyslipidemia, and partial epilepsy. Medications include
metoprolol tartrate, metformin, pitavastatin, and oxcarbazepine. Family
