age 1 of 81
NURS 615 EXAM 2 STUDY GUIDE 2025/2026
COMPLETE QUESTIONS WITH CORRECT DETAILED
ANSWERS || 100% GUARANTEED PASS <BRAND
NEW VERSION>
Gout - med treatment, first line .....Answer.....Allopurinol - first
line agent for lowering urate levels. Xanthine oxidase inhibitor -
Inhibits the enzyme responsible for conversion of hypoxanthine
and xanthine to uric acid
Gout - therapy goals .....Answer.....Management of pain
associated with acute attacks, lowering uric acid levels, lifestyle
management
Opioid FULL agonist .....Answer.....activate opioid receptor fully;
Heroin, morphine, codeine, methadone;
,age 2 of 81
Affinity PLUS efficacy
Opioid PARTIAL agonist .....Answer.....activate opioid receptor to
a lesser degree - you can increase these drug doses but it
usually does not help decrease the pain/effects.
Meds: Buprenorphine & tramadol.
Affinity but low efficacy
Opioid antagonist .....Answer.....bind to opioid receptors without
activating them.
Naloxone (Narcan).
Affinity but no efficacy
Gout caused by .....Answer.....Caused by alteration in purine
metabolism, leads to uric acid buildup.
,age 3 of 81
Hyperuricemia and deposit crystals in joints and tissues
Allopurinol adverse effects .....Answer.....Hepatotoxicity, gout
flair at initiation of therapy, skin rash, multiple drug interactions
Gout LABS to check .....Answer.....LFT, BUN, Creatinine, Uric acid
level, CBC - check these until they are stable
Gout flair up meds .....Answer.....Colchicine, NSAIDs (naproxen is
typical), and glucocorticoids
Colchicine adverse effects .....Answer.....GI - Diarrhea, N/V,
Abdominal cramping; Anemia. Low dose is preferable to high
dose
Corticosteroids .....Answer.....Hormones produced by adrenal
cortex, affect almost all organs in the body maintaining
homeostasis, disease results from inadequate or excess secretion
, age 4 of 81
Corticosteroids .....Answer.....Decrease peripheral uptake of
glucose, glucogenesis in liver
Decrease protein synthesis in muscle, lymph tissue, skin, bone
Lipolysis in fat tissue in extremities; lipogenesis in face & trunk
Decreased circulating eosinophils, lymphocytes, monocytes;
increased PMNs
Blocks generation of fever
Promotes gastric acid secretion; enhances urinary excretion
Decreased proliferation of fibroblasts in conn tissue; delay
healin
Maintains normal contractility of skeletal & cardiac muscle
Increases osteoclastic activity; decreases osteoblastic activity
NURS 615 EXAM 2 STUDY GUIDE 2025/2026
COMPLETE QUESTIONS WITH CORRECT DETAILED
ANSWERS || 100% GUARANTEED PASS <BRAND
NEW VERSION>
Gout - med treatment, first line .....Answer.....Allopurinol - first
line agent for lowering urate levels. Xanthine oxidase inhibitor -
Inhibits the enzyme responsible for conversion of hypoxanthine
and xanthine to uric acid
Gout - therapy goals .....Answer.....Management of pain
associated with acute attacks, lowering uric acid levels, lifestyle
management
Opioid FULL agonist .....Answer.....activate opioid receptor fully;
Heroin, morphine, codeine, methadone;
,age 2 of 81
Affinity PLUS efficacy
Opioid PARTIAL agonist .....Answer.....activate opioid receptor to
a lesser degree - you can increase these drug doses but it
usually does not help decrease the pain/effects.
Meds: Buprenorphine & tramadol.
Affinity but low efficacy
Opioid antagonist .....Answer.....bind to opioid receptors without
activating them.
Naloxone (Narcan).
Affinity but no efficacy
Gout caused by .....Answer.....Caused by alteration in purine
metabolism, leads to uric acid buildup.
,age 3 of 81
Hyperuricemia and deposit crystals in joints and tissues
Allopurinol adverse effects .....Answer.....Hepatotoxicity, gout
flair at initiation of therapy, skin rash, multiple drug interactions
Gout LABS to check .....Answer.....LFT, BUN, Creatinine, Uric acid
level, CBC - check these until they are stable
Gout flair up meds .....Answer.....Colchicine, NSAIDs (naproxen is
typical), and glucocorticoids
Colchicine adverse effects .....Answer.....GI - Diarrhea, N/V,
Abdominal cramping; Anemia. Low dose is preferable to high
dose
Corticosteroids .....Answer.....Hormones produced by adrenal
cortex, affect almost all organs in the body maintaining
homeostasis, disease results from inadequate or excess secretion
, age 4 of 81
Corticosteroids .....Answer.....Decrease peripheral uptake of
glucose, glucogenesis in liver
Decrease protein synthesis in muscle, lymph tissue, skin, bone
Lipolysis in fat tissue in extremities; lipogenesis in face & trunk
Decreased circulating eosinophils, lymphocytes, monocytes;
increased PMNs
Blocks generation of fever
Promotes gastric acid secretion; enhances urinary excretion
Decreased proliferation of fibroblasts in conn tissue; delay
healin
Maintains normal contractility of skeletal & cardiac muscle
Increases osteoclastic activity; decreases osteoblastic activity
