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NURSE 660 EXAM 1 UPDATED EXAM
WITH VERIFIED SOLUTIONS.
1. What level of ANC allows you to give clozapine in the general
population? And in those with benign ethnic neutropenia -
correct answer -greater than or equal to 1500; 1000
2. What neurotransmitters does atypical antipsychotic bind to? -
correct answer -5HT2A, D2
3. What deadly SE is likely to occur when Clozapine is used with
another agent? - correct answer -neuroleptic malignant
syndrome
4. Antagonism of which receptor site by atypical antipsychotics is
responsible for weight gain - correct answer -5HT2C
5. Which medication has the most symptoms related to
restlessness and EPS? - correct answer -Paliparidone
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6. The negative symptoms of schizophrenia are caused by what
situation in the mesocortical pathway - correct answer -hypo
secretion of dopamine
7. What is the leading hypothesis of schizophrenia? - correct
answer -dopamine hypothesis; hyperactivity in the mesolimbic
dopamine pathway, hypoactivity in the mesocortical pathway
8. negative and cognitive symptoms of schizophrenia can be
attributed to hypofunctionality of - correct answer -D1
9. What side effect is unique to Risperdal? - correct answer -
hyperprolactinemia
10. What antipsychotic is FDA approved for suicidal behavior in
schizophrenic and schizoaffective? - correct answer -Clozapine
11. What is the treatment for akethesia? - correct answer -beta-
blockers, anticholinergics (cogentin, benadryl),
benzodiazepines (lorazepam)
NURSE 660 EXAM 1 UPDATED EXAM
WITH VERIFIED SOLUTIONS.
1. What level of ANC allows you to give clozapine in the general
population? And in those with benign ethnic neutropenia -
correct answer -greater than or equal to 1500; 1000
2. What neurotransmitters does atypical antipsychotic bind to? -
correct answer -5HT2A, D2
3. What deadly SE is likely to occur when Clozapine is used with
another agent? - correct answer -neuroleptic malignant
syndrome
4. Antagonism of which receptor site by atypical antipsychotics is
responsible for weight gain - correct answer -5HT2C
5. Which medication has the most symptoms related to
restlessness and EPS? - correct answer -Paliparidone
, Page | 2
6. The negative symptoms of schizophrenia are caused by what
situation in the mesocortical pathway - correct answer -hypo
secretion of dopamine
7. What is the leading hypothesis of schizophrenia? - correct
answer -dopamine hypothesis; hyperactivity in the mesolimbic
dopamine pathway, hypoactivity in the mesocortical pathway
8. negative and cognitive symptoms of schizophrenia can be
attributed to hypofunctionality of - correct answer -D1
9. What side effect is unique to Risperdal? - correct answer -
hyperprolactinemia
10. What antipsychotic is FDA approved for suicidal behavior in
schizophrenic and schizoaffective? - correct answer -Clozapine
11. What is the treatment for akethesia? - correct answer -beta-
blockers, anticholinergics (cogentin, benadryl),
benzodiazepines (lorazepam)
