NSC 830 Advanced Pharmacology Questions and Correct
Answers |Already Graded A+||Brand New Version!!!
Narrow Specturm - CORRECT ANSWER -Treat limited # of organisms, Less likely to disrupt
normal flora, organism identified.
Broad Specturm - CORRECT ANSWER -Treats multiple organisms, more likely to disrupt
normal flora, causative agent unknown.
Why would you select abx? - CORRECT ANSWER -Is antimicrobial therapy indicated, make a
clinical diagnosis, collection of specimens for a cx or lab test, make microbial diagnosis, select
drug.
Extended spectrum - CORRECT ANSWER -treats multiple organisms, more likely to disrupt
normal flora, used when causative organism is unknown.
Gram positive - CORRECT ANSWER -Purple, thick layer
Example of gram positive - CORRECT ANSWER -Group A beta-strep
Strep PNA
Gram negative - CORRECT ANSWER -Red or pink, thin layer
Example of gram negative - CORRECT ANSWER -H. influenza
N. Gonoccocus
Atypical Organism - CORRECT ANSWER -colorless, no layer
,Example of Atypical organism - CORRECT ANSWER -Macrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-lactum abx - CORRECT ANSWER -True
Risk factors for Drug Resistant Strep PNA (DRSP) - CORRECT ANSWER -Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day long term).
Treatment for Drug Resistant Strep PNA - CORRECT ANSWER -High dose amoxicillin 3-
4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... - CORRECT ANSWER -Allergy history (PCN-
risk of cross allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? - CORRECT ANSWER -tetracyclines
fluoroquinolone
, Do immunocompromised patients get bactericidal or baceriostiatic? - CORRECT ANSWER -
Bactericidals
What are bactericidals? - CORRECT ANSWER -Kills bacteria
What are bacteriostatic? - CORRECT ANSWER -Restrains production of bacteria. The patient
needs a good immune system.
Minimum inhibitory concentration (MIC) - CORRECT ANSWER -Min. amount of abx used to
inhibit growth of bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... - CORRECT ANSWER -Take ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)
General side effects of abx - CORRECT ANSWER -Hypersensitivity: (allergic reaction-rash,
itching, LBP, wheezing, SOA).
Diarrhea: make sure to report blood, mucous
Superinfection: Due to disruption of normal flora (oral thrush, yeast infection)
True or False: Is extended care more likely to cause diarrhea? - CORRECT ANSWER -True
Examples of Beta-Lactam Abx? - CORRECT ANSWER -PCN & Cephalosporins
What do Beta-Lactam abx have on them? - CORRECT ANSWER -A ring- that works by
disrupting the biosynthesis of the cell wall.
Intact ring is essential for antibacterial activity? True or False - CORRECT ANSWER -True
Answers |Already Graded A+||Brand New Version!!!
Narrow Specturm - CORRECT ANSWER -Treat limited # of organisms, Less likely to disrupt
normal flora, organism identified.
Broad Specturm - CORRECT ANSWER -Treats multiple organisms, more likely to disrupt
normal flora, causative agent unknown.
Why would you select abx? - CORRECT ANSWER -Is antimicrobial therapy indicated, make a
clinical diagnosis, collection of specimens for a cx or lab test, make microbial diagnosis, select
drug.
Extended spectrum - CORRECT ANSWER -treats multiple organisms, more likely to disrupt
normal flora, used when causative organism is unknown.
Gram positive - CORRECT ANSWER -Purple, thick layer
Example of gram positive - CORRECT ANSWER -Group A beta-strep
Strep PNA
Gram negative - CORRECT ANSWER -Red or pink, thin layer
Example of gram negative - CORRECT ANSWER -H. influenza
N. Gonoccocus
Atypical Organism - CORRECT ANSWER -colorless, no layer
,Example of Atypical organism - CORRECT ANSWER -Macrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-lactum abx - CORRECT ANSWER -True
Risk factors for Drug Resistant Strep PNA (DRSP) - CORRECT ANSWER -Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day long term).
Treatment for Drug Resistant Strep PNA - CORRECT ANSWER -High dose amoxicillin 3-
4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... - CORRECT ANSWER -Allergy history (PCN-
risk of cross allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? - CORRECT ANSWER -tetracyclines
fluoroquinolone
, Do immunocompromised patients get bactericidal or baceriostiatic? - CORRECT ANSWER -
Bactericidals
What are bactericidals? - CORRECT ANSWER -Kills bacteria
What are bacteriostatic? - CORRECT ANSWER -Restrains production of bacteria. The patient
needs a good immune system.
Minimum inhibitory concentration (MIC) - CORRECT ANSWER -Min. amount of abx used to
inhibit growth of bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... - CORRECT ANSWER -Take ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)
General side effects of abx - CORRECT ANSWER -Hypersensitivity: (allergic reaction-rash,
itching, LBP, wheezing, SOA).
Diarrhea: make sure to report blood, mucous
Superinfection: Due to disruption of normal flora (oral thrush, yeast infection)
True or False: Is extended care more likely to cause diarrhea? - CORRECT ANSWER -True
Examples of Beta-Lactam Abx? - CORRECT ANSWER -PCN & Cephalosporins
What do Beta-Lactam abx have on them? - CORRECT ANSWER -A ring- that works by
disrupting the biosynthesis of the cell wall.
Intact ring is essential for antibacterial activity? True or False - CORRECT ANSWER -True
