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November 2025 Australia Edition | AHPRA Medication Calculation Exam Complete Mastery Guide for Internationally Qualified Nurses | Advanced Dosage Calculations, Drug Safety Principles, High-Accuracy Practice Questions, Clinical Scenarios, Metric Conversion

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This advanced November 2025 AHPRA Medication Calculation Exam Mastery Guide is designed for internationally qualified nurses preparing for registration in Australia. It covers essential nursing math skills, dosage calculations, IV drip rates, safe medication administration principles, pediatric and adult dosing, and metric conversions aligned with AHPRA, NCLEX-AU, and OSCE Australia standards. With updated practice questions, step-by-step solutions, and real clinical medication scenarios, this guide provides everything you need to master medication calculations with confidence, improve accuracy, and pass the AHPRA Medication Calculation Exam on your first attempt.

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• November 2025 AustrAliA editioN | AHPrA
medicAtioN cAlculAtioN exAm comPlete
mAstery Guide for iNterNAtioNAlly
QuAlified Nurses | AdvANced dosAGe
cAlculAtioNs, druG sAfety PriNciPles, HiGH-
AccurAcy PrActice QuestioNs, cliNicAl
sceNArios, metric coNversioNs & Nclex-
Au/osce-AliGNed medicAtioN comPeteNcy
review

Question 1
A patient is prescribed 500 mg of a medication. The medication is available in 250
mg tablets. How many tablets should the nurse administer?
A) 1
B) 2
C) 3
D) 4
Correct Option: B
Rationale:
To calculate the number of tablets, divide the prescribed dose by the dosage per tablet:
Prescribed dose 500 mg
Number of tablets = = = 2 tablets
Dose per tablet 250 mg




Question 2
A doctor orders 1.5 liters of intravenous fluid to be infused over 12 hours. What is
the infusion rate in mL per hour?
A) 125 mL/hour
B) 150 mL/hour
C) 175 mL/hour
D) 200 mL/hour

• Correct Option: B
Rationale:
To determine the infusion rate per hour, convert liters to mL (1 L = 1000 mL) and then
divide by the number of hours:

, 1500 mL
Infusion rate = = 125 mL/hour
12 hours




Question 3
A patient requires 0.4 mg of a medication. The medication is available in a
concentration of 200 mcg/mL. How many mL should be administered?
A) 1 mL
B) 2 mL
C) 3 mL
D) 4 mL
Correct Option: B
Rationale:
First, convert mg to mcg (1 mg = 1000 mcg):

0.4 mg = 400 mcg


Next, use the concentration to find the volume:
Required dose 400 mcg
Volume = = = 2 mL
Concentration 200 mcg/mL




Question 4
A pediatric patient weighs 15 kg. The prescribed medication dosage is 10 mg/kg.
How much medication should be administered to this patient?
A) 100 mg
B) 150 mg
C) 200 mg
D) 250 mg
Correct Option: B
Rationale:
Calculate the total dose based on weight:

Total dose = Weight in kg × Dosage = 15 kg × 10 mg/kg = 150 mg




Question 5

,A medication is to be given at a rate of 1.5 mg/minute. How much medication will
be administered in 2 hours?
A) 120 mg
B) 150 mg
C) 180 mg
D) 240 mg
Correct Option: C
Rationale:
First, convert hours to minutes (2 hours = 120 minutes) and then calculate the total
medication:

Total medication = Rate × Time = 1.5 mg/minute × 120 minutes = 180 mg


Question 6
A patient is to receive 250 mL of a medication over 4 hours. How many mL per hour
should the nurse set the infusion pump?
A) 50 mL/hour
B) 60 mL/hour
C) 70 mL/hour
D) 75 mL/hour
Correct Option: B
Rationale:
To find the infusion rate per hour, divide the total volume by the duration in hours:
250 mL
Infusion rate = = 62.5 mL/hour ≈ 63 mL/hour
4 hours




Question 7
A medication is prescribed at a dosage of 0.2 mg/kg. For a patient weighing 70 kg,
what is the total dose in mg?
A) 10 mg
B) 12 mg
C) 14 mg
D) 15 mg
Correct Option: C
Rationale:
Calculate the dose based on weight:

, Total dose = 70 kg × 0.2 mg/kg = 14 mg




Question 8
A doctor orders 5 g of a medication. The medication is available in 1 g vials. How
many vials should the nurse prepare?
A) 3
B) 4
C) 5
D) 6
Correct Option: C
Rationale:
To determine the number of vials needed, divide the total dose by the dosage per vial:
5g
Number of vials = = 5 vials
1 g/vial




Question 9
A patient is ordered to receive 1 L of normal saline over 8 hours. What is the drip
rate in mL/hour?
A) 100 mL/hour
B) 125 mL/hour
C) 150 mL/hour
D) 175 mL/hour
Correct Option: B
Rationale:
Convert liters to mL and then compute the hourly rate:
1000 mL
Drip rate = = 125 mL/hour
8 hours




Question 10
A patient requires a dose of 600 mcg of a medication. The medication is available
as 0.5 mg tablets. How many tablets should be administered?

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