The heart: seat of emotions
Emotions are associated with the heart
Heart beat is sensitive to endocrine and nervous signals – this endocrinal activation
of heart beat is felt
Blood pressure drops heart beats faster
Complexity of the heart
Paired groups of angioblasts migrate to midline form
a single ventral tube (anterior in the embryo)
migration of neural crest cells longitudinal kinking
(looping) of the tube formation of septa (split into left
and right side) switch in the connections to the great
arteries formation of valves
1% of life-borns has a congenital heart malformation
(defect in structure of heart or in great vessels)
Development of the heart
Development of the heart is tightly connected to development of the
coelom (secondary body cavity)
Heart development in fish
Heart is positioned behind the gills (the neck) + single blood circulation
Blood flow from body sinus atrium (boezem) ventricle (kamer)
bulbus blood flow from heart to gills
So, blood flow from ventral to front and dorsal to back
Heart development in human
Heart lies in chest (borst) + double blood circulation (formation of septa is
the beginning of the double circulation) (begins in reptiles)
o Left part: goes to the body – aorta
o Right part: goes to the lungs – pulmonary artery (voorheen
monde deze ook uit in de arota)
The double blood circulation cause that mammals could run much
faster than a reptile
The aorta switch (day 35-45) – switch from reptiles to mammels
D-loop: correct connection aorta and pulmonary artery – aorta
culed to the right
o Solitus normal: Aorta left and down pulmonary right and
up
o D-TGA: Aorta left and up pulmonary right and down
L-loop: incorrect connection aorta and
pulmonary artery – aorta curled to the left
o Inverted normal: Aorta right and down
pulmonary left and up
o L-TGA: Aorta right and up pulmonary left
and down
Emotions are associated with the heart
Heart beat is sensitive to endocrine and nervous signals – this endocrinal activation
of heart beat is felt
Blood pressure drops heart beats faster
Complexity of the heart
Paired groups of angioblasts migrate to midline form
a single ventral tube (anterior in the embryo)
migration of neural crest cells longitudinal kinking
(looping) of the tube formation of septa (split into left
and right side) switch in the connections to the great
arteries formation of valves
1% of life-borns has a congenital heart malformation
(defect in structure of heart or in great vessels)
Development of the heart
Development of the heart is tightly connected to development of the
coelom (secondary body cavity)
Heart development in fish
Heart is positioned behind the gills (the neck) + single blood circulation
Blood flow from body sinus atrium (boezem) ventricle (kamer)
bulbus blood flow from heart to gills
So, blood flow from ventral to front and dorsal to back
Heart development in human
Heart lies in chest (borst) + double blood circulation (formation of septa is
the beginning of the double circulation) (begins in reptiles)
o Left part: goes to the body – aorta
o Right part: goes to the lungs – pulmonary artery (voorheen
monde deze ook uit in de arota)
The double blood circulation cause that mammals could run much
faster than a reptile
The aorta switch (day 35-45) – switch from reptiles to mammels
D-loop: correct connection aorta and pulmonary artery – aorta
culed to the right
o Solitus normal: Aorta left and down pulmonary right and
up
o D-TGA: Aorta left and up pulmonary right and down
L-loop: incorrect connection aorta and
pulmonary artery – aorta curled to the left
o Inverted normal: Aorta right and down
pulmonary left and up
o L-TGA: Aorta right and up pulmonary left
and down
