Test Bank For Modern Blood Banking &
Transfusion Practices Chapter 1-29 Complete
Guide
Each unit of whole blood or rbcs will increase the hematocrit 3%-5%, so 2 units of rbcs
will increase the hematocrit by twice as must as 1 unit of whole blood - answers How
would the hematocrit of a patient with chronic anemia be affected by the transfusion of a
unit of Whole Blood containing 475 mL of blood, vs 2 units of Red Blood Cells each with
a total volume of 250 mL?
a. patient's hematocrit would be equally affected by the Whole Blood or the Red Blood
cells
b. Red blood cells would provide twice the increment in hematocrit as the whole blood
c. whole blood would provide twice the increment in hematocrit as the red blood cells
d. whole blood would provide a change in hematocrit slightly less than the red blood
cells
c
For emergency transfusions, group O-rbc units should be used. - answers After
checking the inventory, it was noted that there were no units on the shelf marked "May
issue as Uncrossmatched: For Emergency Only". Which of the following should be
placed on this shelf?
a. 1 unit of each of the ABO blood groups
b. units of group O, Rh-positive whole blood
c. units of group O, Rh-negative red blood cells
d. any units that are expiring at midnight
d
Granulocyte transfusions may be indicated for severely neutropenic patients with
infection not controlled by antibiotic therapy, who are expected to recover bone marrow
production of white cells. - answers The primary indication for granulocyte transfusion
is:
a. prophylactic treatment for infection
b. additional supportive therapy in those patients who are responsive to antibiotic
therapy
c. clinical situations where bone marrow recovery is not anticipated
d. severe neutropenia with an infection that is nonresponsive to antibiotic therapy
b
,Each unit of rbcs is expected to increase the hemoglobin level by 1-1.5 g/dl (10-15 g/L).
- answers A 42 yr old male of average body mass has a history of chronic anemia
requiring transfusion support. Two units of red blood cells are transfused. If the
pretransfusion hemoglobin was 7.0 g/dl (70g/L), the expected posttransfusion
hemoglobin concentration should be:
a. 8.0 g/dl (80g/L)
b. 9.0 g/dl (90g/L)
c. 10.0 g/dl (100 g/L)
d. 11.0 g/dl (110 g/L)
b
Each unit of rbcs is expected to increase the hematocrit level 3%-5%, so it would take 2
units to raise the level 6%. - answers How many units of red blood cells are required to
raise the hematocrit of a 70 kg nonbleeding man from 24% to 30%?
a. 1
b. 2
c. 3
d. 4
c
CMV-seronegative or leukoreduced blood products should be administered to
immunocompromised patients, including bone marrow and hematopoietic cell transplant
recipients. - answers For which of the following transfusion candidates would CMV-
seronegative blood be most likely indicated?
a. renal dialysis patients
b. sickle cell patient
c. bone marrow and hematopoietic cell transplant recipients
d. CMV-seropositive patients
b
Cryoprecipitate contains ABO antibodies so one should consider giving ABO
compatible, especially when infusing large volumes. - answers Although ABO
compatibility is preferred, ABO incompatible product may be administered when
transfusing:
a. Single-Donor Plasma
b. Cryoprecipitated AHF
c. FFP
d. Granulocytes
,d
Class I HLA antigens on platelets are a known cause for platelet refractoriness.
Leukoreduction of blood products is used as a mechanism to reduce or prevent patients
from developing antibodies. - answers Transfusion of plateletpheresis products from
HLA-compatible donors is the preferred treatment:
a. recently diagnosed cases of TTP with severe thrombocytopenia
b. acute leukemia in relapse with neutropenia, thrombocytopenia and sepsis
c. immune thrombocytopenic purpura
d. severely thrombocytopenic patients, known to be refractory to random donor platelets
a
Patients with IgA deficiency who have had anaphylactic transfusion reactions should
receive washed rbcs. Anaphylactic reactions are typically caused by anti-IgA in the
recipient. Washing removes plasma IgA from the donor unit cells - answers Washed red
blood cells are indicated in which of the following situations?
a. an IgA-deficient patient with a history of transfusion-associated anaphylaxis
b. a pregnant woman with a history of hemolytic disease of the newborn
c. a patient with a positive DAT and red cell autoantibody
d. a newborn with a hematocrit of <30%
d
FFP should be ABO compatible with the recipient's RBCs. Avoid FFP with antibodies to
A or B antigens the patient may have. Group A plasma has anti-B, and should only be
transfused to A or O recipients. - answers Which of the following is consistent with
standard blood bank procedure governing the infusion of FFP?
a. only blood group-specific plasma may be administered
b. group O may be administered to recipients of all blood groups
c. group AB may be administered to AB recipients only
d. group A may be administered to both A and O recipients
d
FFP should be ABO compatible with the recipient's RBCs. Avoid FFP with ABO
antibodies to A or B antigens the patient may have. - answers A patient who is group
AB, Rh-negative needs 2 units of FFP. Which of the following units of plasma would be
most acceptable for transfusion?
a. group O, Rh-negative
b. group A, Rh-negative
c. group B, Rh-positive
, d. group AB, Rh-positive
b
Each unit of platelets should increase the count 5,000 - 10,000/uL (5,000-10,000/L). -
answers What increment of platelets/uL (platelets/L), in the typical 70 kg human, is
expected to results from each single unit of Platelets transfused to a non-HLA-
sensitized recipient?
a. 3,000-5,000
b. 5,000-10,000
c. 20,000-25,000
d. 25,000-30,000
c
Functional abnormalities are frequent in hypoproliferative thrombocytopenia. Decreased
platelets is not an outcome of a hemolytic transfusion reaction, posttransfusion purpura
is usually self-limiting and is due to an antibody to a specific platelet antigen, immune
thromboycytopenia purpura patients have low platelet counts but rarely have
hemorrhage. - answers Platelet transfusions are of most value in treating:
a. hemolytic transfusion reaction
b. posttransfusion purpura
c. functional platelet abnormalities
d. immune thrombocytopenic purpura
d
Washing red blood cells with saline removes donor plasma and IgA, and prevents
anaphylactic reactions due to anti-IgA in the recipient. - answers Washed red blood
cells would be the product of choice for a patient with:
a. multiple red cell alloantibodies
b. an increased risk of hepatitis infection
c. warm autoimmune hemolytic anemia
d. anti-IgA antibodies
b
Anaphylactic transfusion reactions are distinguished from other types of reactions by:
1. the absence of fever
2. the reactions are sudden in onset after infusion of only a few mL of blood.
Since the reaction is due to anti-IgA, washing the donor red blood cells to remove all
plasma protein is indicated. Alternatively, blood products from IgA-deficient donors may
be used. - answers A patient received about 15 ml of compatible blood and developed
Transfusion Practices Chapter 1-29 Complete
Guide
Each unit of whole blood or rbcs will increase the hematocrit 3%-5%, so 2 units of rbcs
will increase the hematocrit by twice as must as 1 unit of whole blood - answers How
would the hematocrit of a patient with chronic anemia be affected by the transfusion of a
unit of Whole Blood containing 475 mL of blood, vs 2 units of Red Blood Cells each with
a total volume of 250 mL?
a. patient's hematocrit would be equally affected by the Whole Blood or the Red Blood
cells
b. Red blood cells would provide twice the increment in hematocrit as the whole blood
c. whole blood would provide twice the increment in hematocrit as the red blood cells
d. whole blood would provide a change in hematocrit slightly less than the red blood
cells
c
For emergency transfusions, group O-rbc units should be used. - answers After
checking the inventory, it was noted that there were no units on the shelf marked "May
issue as Uncrossmatched: For Emergency Only". Which of the following should be
placed on this shelf?
a. 1 unit of each of the ABO blood groups
b. units of group O, Rh-positive whole blood
c. units of group O, Rh-negative red blood cells
d. any units that are expiring at midnight
d
Granulocyte transfusions may be indicated for severely neutropenic patients with
infection not controlled by antibiotic therapy, who are expected to recover bone marrow
production of white cells. - answers The primary indication for granulocyte transfusion
is:
a. prophylactic treatment for infection
b. additional supportive therapy in those patients who are responsive to antibiotic
therapy
c. clinical situations where bone marrow recovery is not anticipated
d. severe neutropenia with an infection that is nonresponsive to antibiotic therapy
b
,Each unit of rbcs is expected to increase the hemoglobin level by 1-1.5 g/dl (10-15 g/L).
- answers A 42 yr old male of average body mass has a history of chronic anemia
requiring transfusion support. Two units of red blood cells are transfused. If the
pretransfusion hemoglobin was 7.0 g/dl (70g/L), the expected posttransfusion
hemoglobin concentration should be:
a. 8.0 g/dl (80g/L)
b. 9.0 g/dl (90g/L)
c. 10.0 g/dl (100 g/L)
d. 11.0 g/dl (110 g/L)
b
Each unit of rbcs is expected to increase the hematocrit level 3%-5%, so it would take 2
units to raise the level 6%. - answers How many units of red blood cells are required to
raise the hematocrit of a 70 kg nonbleeding man from 24% to 30%?
a. 1
b. 2
c. 3
d. 4
c
CMV-seronegative or leukoreduced blood products should be administered to
immunocompromised patients, including bone marrow and hematopoietic cell transplant
recipients. - answers For which of the following transfusion candidates would CMV-
seronegative blood be most likely indicated?
a. renal dialysis patients
b. sickle cell patient
c. bone marrow and hematopoietic cell transplant recipients
d. CMV-seropositive patients
b
Cryoprecipitate contains ABO antibodies so one should consider giving ABO
compatible, especially when infusing large volumes. - answers Although ABO
compatibility is preferred, ABO incompatible product may be administered when
transfusing:
a. Single-Donor Plasma
b. Cryoprecipitated AHF
c. FFP
d. Granulocytes
,d
Class I HLA antigens on platelets are a known cause for platelet refractoriness.
Leukoreduction of blood products is used as a mechanism to reduce or prevent patients
from developing antibodies. - answers Transfusion of plateletpheresis products from
HLA-compatible donors is the preferred treatment:
a. recently diagnosed cases of TTP with severe thrombocytopenia
b. acute leukemia in relapse with neutropenia, thrombocytopenia and sepsis
c. immune thrombocytopenic purpura
d. severely thrombocytopenic patients, known to be refractory to random donor platelets
a
Patients with IgA deficiency who have had anaphylactic transfusion reactions should
receive washed rbcs. Anaphylactic reactions are typically caused by anti-IgA in the
recipient. Washing removes plasma IgA from the donor unit cells - answers Washed red
blood cells are indicated in which of the following situations?
a. an IgA-deficient patient with a history of transfusion-associated anaphylaxis
b. a pregnant woman with a history of hemolytic disease of the newborn
c. a patient with a positive DAT and red cell autoantibody
d. a newborn with a hematocrit of <30%
d
FFP should be ABO compatible with the recipient's RBCs. Avoid FFP with antibodies to
A or B antigens the patient may have. Group A plasma has anti-B, and should only be
transfused to A or O recipients. - answers Which of the following is consistent with
standard blood bank procedure governing the infusion of FFP?
a. only blood group-specific plasma may be administered
b. group O may be administered to recipients of all blood groups
c. group AB may be administered to AB recipients only
d. group A may be administered to both A and O recipients
d
FFP should be ABO compatible with the recipient's RBCs. Avoid FFP with ABO
antibodies to A or B antigens the patient may have. - answers A patient who is group
AB, Rh-negative needs 2 units of FFP. Which of the following units of plasma would be
most acceptable for transfusion?
a. group O, Rh-negative
b. group A, Rh-negative
c. group B, Rh-positive
, d. group AB, Rh-positive
b
Each unit of platelets should increase the count 5,000 - 10,000/uL (5,000-10,000/L). -
answers What increment of platelets/uL (platelets/L), in the typical 70 kg human, is
expected to results from each single unit of Platelets transfused to a non-HLA-
sensitized recipient?
a. 3,000-5,000
b. 5,000-10,000
c. 20,000-25,000
d. 25,000-30,000
c
Functional abnormalities are frequent in hypoproliferative thrombocytopenia. Decreased
platelets is not an outcome of a hemolytic transfusion reaction, posttransfusion purpura
is usually self-limiting and is due to an antibody to a specific platelet antigen, immune
thromboycytopenia purpura patients have low platelet counts but rarely have
hemorrhage. - answers Platelet transfusions are of most value in treating:
a. hemolytic transfusion reaction
b. posttransfusion purpura
c. functional platelet abnormalities
d. immune thrombocytopenic purpura
d
Washing red blood cells with saline removes donor plasma and IgA, and prevents
anaphylactic reactions due to anti-IgA in the recipient. - answers Washed red blood
cells would be the product of choice for a patient with:
a. multiple red cell alloantibodies
b. an increased risk of hepatitis infection
c. warm autoimmune hemolytic anemia
d. anti-IgA antibodies
b
Anaphylactic transfusion reactions are distinguished from other types of reactions by:
1. the absence of fever
2. the reactions are sudden in onset after infusion of only a few mL of blood.
Since the reaction is due to anti-IgA, washing the donor red blood cells to remove all
plasma protein is indicated. Alternatively, blood products from IgA-deficient donors may
be used. - answers A patient received about 15 ml of compatible blood and developed
