PCB 3233 – Immunology Exam 4 Question Bank with
Correct, Verified, and Detailed Answers (University Course
Study Material)
Introduction:
This document contains a complete set of Exam 4 immunology
questions for PCB 3233, accompanied by correct, verified, and fully
explained answers. The material covers key immune mechanisms,
cellular responses, hypersensitivities, immunological pathways, and
clinical immunology concepts typically assessed in upper-level
undergraduate immunology courses. It functions as a study guide,
test bank, and practice resource aligned with standard course
content.
Exam Questions and Answers
True or False? T-cells have a very short half life? --- correct precise
answer ---Falso
Vascular addressin(CD34) bind to --- correct precise answer ---
Selectins
"Which specific selection did I ask you to know about?" --- correct
precise answer ---NONE OF THE ABOVE
Super immunoglobulin superfamily binds to --- correct precise
answer ---integrins
,L-Selectin binds to --- correct precise answer ---GlyCam-1, CD34
and MAdCAM-1
LFA-1 binds to --- correct precise answer ---ICAMs
CD2 binds to --- correct precise answer ---LFA-3
CD34 binds to --- correct precise answer ---L-selectin
Mature dendritic cell surface marker --- correct precise answer ---
DC-SIGN
DC-SIGN is on which cell? --- correct precise answer ---Mature
dendritic cell
Do we need adhesion molecules for T-cell binding? --- correct
precise answer ---yes
Do we increase the affinity in TCR? --- correct precise answer ---
No, because it is not secreted and addressins molecules are
surrounded
,CD28 is on --- correct precise answer ---T-cell
Which CDR makes most contact with peptide? --- correct precise
answer ---CDR 3
Which CDR makes most contact with MHC --- correct precise
answer ---CDR 1&2
MHC 2 can have how long of a peptide chain? --- correct precise
answer ---13-25
MHC 1 can have how long of a peptide chain? --- correct precise
answer ---8,9 or 10
B7 expression is a direct consequence of --- correct precise answer
---infection
Peripheral tolerance has no --- correct precise answer ---B-7
CTLA-4 --- correct precise answer ---down regulates proliferation
Phagocytosis is done by --- correct precise answer ---macrophages
and immature dendritic cells
, Co-stimulatory signal --- correct precise answer ---B7:CD28
Mature dendritic cells secretes --- correct precise answer ---CCL18
which attracts naive T-cells
What chemokine/cytokine calls B-cells over to follicle? --- correct
precise answer ---CXCL13
What is another name for mature Dendritic cells? --- correct
precise answer ---Interdigitating reticular cells
ITAMs --- correct precise answer ---Immunoreceptor tyrosine-
based activation motifs
On cytoplasmic tails of T-cells
associates with protein tyrosine kinase
c-SMAC --- correct precise answer ---Allows clustering of
receptors-co-receptors and signaling molecules
TCR,CD2,CD4,CD8,CD28, and PkC-theta
Correct, Verified, and Detailed Answers (University Course
Study Material)
Introduction:
This document contains a complete set of Exam 4 immunology
questions for PCB 3233, accompanied by correct, verified, and fully
explained answers. The material covers key immune mechanisms,
cellular responses, hypersensitivities, immunological pathways, and
clinical immunology concepts typically assessed in upper-level
undergraduate immunology courses. It functions as a study guide,
test bank, and practice resource aligned with standard course
content.
Exam Questions and Answers
True or False? T-cells have a very short half life? --- correct precise
answer ---Falso
Vascular addressin(CD34) bind to --- correct precise answer ---
Selectins
"Which specific selection did I ask you to know about?" --- correct
precise answer ---NONE OF THE ABOVE
Super immunoglobulin superfamily binds to --- correct precise
answer ---integrins
,L-Selectin binds to --- correct precise answer ---GlyCam-1, CD34
and MAdCAM-1
LFA-1 binds to --- correct precise answer ---ICAMs
CD2 binds to --- correct precise answer ---LFA-3
CD34 binds to --- correct precise answer ---L-selectin
Mature dendritic cell surface marker --- correct precise answer ---
DC-SIGN
DC-SIGN is on which cell? --- correct precise answer ---Mature
dendritic cell
Do we need adhesion molecules for T-cell binding? --- correct
precise answer ---yes
Do we increase the affinity in TCR? --- correct precise answer ---
No, because it is not secreted and addressins molecules are
surrounded
,CD28 is on --- correct precise answer ---T-cell
Which CDR makes most contact with peptide? --- correct precise
answer ---CDR 3
Which CDR makes most contact with MHC --- correct precise
answer ---CDR 1&2
MHC 2 can have how long of a peptide chain? --- correct precise
answer ---13-25
MHC 1 can have how long of a peptide chain? --- correct precise
answer ---8,9 or 10
B7 expression is a direct consequence of --- correct precise answer
---infection
Peripheral tolerance has no --- correct precise answer ---B-7
CTLA-4 --- correct precise answer ---down regulates proliferation
Phagocytosis is done by --- correct precise answer ---macrophages
and immature dendritic cells
, Co-stimulatory signal --- correct precise answer ---B7:CD28
Mature dendritic cells secretes --- correct precise answer ---CCL18
which attracts naive T-cells
What chemokine/cytokine calls B-cells over to follicle? --- correct
precise answer ---CXCL13
What is another name for mature Dendritic cells? --- correct
precise answer ---Interdigitating reticular cells
ITAMs --- correct precise answer ---Immunoreceptor tyrosine-
based activation motifs
On cytoplasmic tails of T-cells
associates with protein tyrosine kinase
c-SMAC --- correct precise answer ---Allows clustering of
receptors-co-receptors and signaling molecules
TCR,CD2,CD4,CD8,CD28, and PkC-theta
