COMSAE PHASE 2 EXAM WITH PRACTICE
QUESTIONS AND CORRECT DETAILED ANSWERS
NEW MODIFIED TESTED AND APPROVED
What is the strongest study design to evaluate the efficacy of yoga for patients
with ADHD?
Randomized clinical trial.
What was the smoking history of the 56-year-old man with a lesion on his
tongue?
A 60 pack-year history.
What did the 56-year-old man refuse after counseling regarding his tongue
lesion?
Further evaluation of the lesion.
What is the main concern of the 56-year-old man regarding his treatment
options?
He does not want 'a bunch of doctors messing' with him.
Page 1 of 98
,What is the significance of a p-value of 0.049 in the hypertension study?
It indicates that the results are statistically significant, with a less than 5%
probability that the results are due to chance.
In the study evaluating combination therapy for hypertension, what was the
control treatment?
Hydrochlorothiazide alone.
What type of study design is a randomized clinical trial?
A study design that randomly assigns participants to treatment or control groups
to evaluate the efficacy of interventions.
What is the purpose of a case control study?
To compare individuals with a specific condition to those without the condition
to identify potential risk factors.
What does the term 'cross-sectional study' refer to?
A study design that analyzes data from a population at a specific point in time.
Page 2 of 98
,What is the primary outcome measure in the Alzheimer's disease study?
The classification of a patient as showing progression or no progression of
disease as measured by a standard neuropsychological test of memory.
How many patients showed progression with the experimental drug in the
Alzheimer's study?
50 patients.
What is the total number of patients in the Alzheimer's study?
240 patients.
What calculation would best determine how many patients need to be treated for
one successful outcome in the Alzheimer's study?
[50/(50 + 70)] / [75/(75 + 45)]
What was the reduction in systolic blood pressure with combination therapy
compared to hydrochlorothiazide alone?
Page 3 of 98
, 25 mmHg (95% CI = 15-35 mmHg, p = 0.049).
What conclusion can be drawn from the study comparing combination therapy
to hydrochlorothiazide alone?
There is an approximate 5% probability that the decrease in systolic blood
pressure was due to chance.
Which study design is most appropriate to evaluate the relationship between
nasopharyngeal cancer and exposure to wood products?
Case control study.
What is the role of a cohort study in medical research?
To follow a group of individuals over time to assess the effects of certain
exposures on outcomes.
What is the primary focus of an ecological study?
To examine the relationships between environmental factors and health
outcomes at a population level.
Page 4 of 98
QUESTIONS AND CORRECT DETAILED ANSWERS
NEW MODIFIED TESTED AND APPROVED
What is the strongest study design to evaluate the efficacy of yoga for patients
with ADHD?
Randomized clinical trial.
What was the smoking history of the 56-year-old man with a lesion on his
tongue?
A 60 pack-year history.
What did the 56-year-old man refuse after counseling regarding his tongue
lesion?
Further evaluation of the lesion.
What is the main concern of the 56-year-old man regarding his treatment
options?
He does not want 'a bunch of doctors messing' with him.
Page 1 of 98
,What is the significance of a p-value of 0.049 in the hypertension study?
It indicates that the results are statistically significant, with a less than 5%
probability that the results are due to chance.
In the study evaluating combination therapy for hypertension, what was the
control treatment?
Hydrochlorothiazide alone.
What type of study design is a randomized clinical trial?
A study design that randomly assigns participants to treatment or control groups
to evaluate the efficacy of interventions.
What is the purpose of a case control study?
To compare individuals with a specific condition to those without the condition
to identify potential risk factors.
What does the term 'cross-sectional study' refer to?
A study design that analyzes data from a population at a specific point in time.
Page 2 of 98
,What is the primary outcome measure in the Alzheimer's disease study?
The classification of a patient as showing progression or no progression of
disease as measured by a standard neuropsychological test of memory.
How many patients showed progression with the experimental drug in the
Alzheimer's study?
50 patients.
What is the total number of patients in the Alzheimer's study?
240 patients.
What calculation would best determine how many patients need to be treated for
one successful outcome in the Alzheimer's study?
[50/(50 + 70)] / [75/(75 + 45)]
What was the reduction in systolic blood pressure with combination therapy
compared to hydrochlorothiazide alone?
Page 3 of 98
, 25 mmHg (95% CI = 15-35 mmHg, p = 0.049).
What conclusion can be drawn from the study comparing combination therapy
to hydrochlorothiazide alone?
There is an approximate 5% probability that the decrease in systolic blood
pressure was due to chance.
Which study design is most appropriate to evaluate the relationship between
nasopharyngeal cancer and exposure to wood products?
Case control study.
What is the role of a cohort study in medical research?
To follow a group of individuals over time to assess the effects of certain
exposures on outcomes.
What is the primary focus of an ecological study?
To examine the relationships between environmental factors and health
outcomes at a population level.
Page 4 of 98
