NSG 552 PsychoPharmacology Wilkes
Exam 3 Study Guide Fall Exam
Questions and Answers Graded A+
First Line Treatments for alcohol use disorder (according to Study Guide &
Dynamed) - Correct answer-naltrexone and acamprosate
Second Line Treatments for alcohol use disorder (according to study guide but not
dynamed) - Correct answer-Disulfuram and Bupropion (not FDA approved for
ETOH but second line according to study guide)
Second Line Treatment for alcohol use disorder (according to Dynamed) - Correct
answer-Disulfuram
Other off label medications for alcohol use disorder according to Dynamed -
Correct answer-Topiramate, gabapentin, baclofen
Other off label medications for alcohol use disorder according to Stahl's - Correct
answer-Topiramate, ondansetron
MOA of Naltrexone - Correct answer-Opioid Receptor Antagonist
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, MOA of Acamprosate - Correct answer-- weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
MOA of Disulfuram - Correct answer-inhibits enzyme (aldehyde dehydrogenase)
in the liver
Bupropions role in alcohol use disorder - Correct answer-Can diminish cravings
for etoh, treat underlying anxiety/depression
Safety Risk associated with bupropion and etoh - Correct answer-bupropion
increases the risk of seizures in those going through etoh withdrawal
s/s ETOH intoxication - Correct answer-impaired fine motor control, impaired
judgement and coordination, ataxic gait, poor balance, lethargy, difficulty sitting
upright, difficulty with memory and sitting upright, N/V, coma in levels 300mg/dL
and over with respiratory depression and death possible
S/S of etoh withdrawal - Correct answer-Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
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Exam 3 Study Guide Fall Exam
Questions and Answers Graded A+
First Line Treatments for alcohol use disorder (according to Study Guide &
Dynamed) - Correct answer-naltrexone and acamprosate
Second Line Treatments for alcohol use disorder (according to study guide but not
dynamed) - Correct answer-Disulfuram and Bupropion (not FDA approved for
ETOH but second line according to study guide)
Second Line Treatment for alcohol use disorder (according to Dynamed) - Correct
answer-Disulfuram
Other off label medications for alcohol use disorder according to Dynamed -
Correct answer-Topiramate, gabapentin, baclofen
Other off label medications for alcohol use disorder according to Stahl's - Correct
answer-Topiramate, ondansetron
MOA of Naltrexone - Correct answer-Opioid Receptor Antagonist
©COPYRIGHT 2025, ALL RIGHTS RESERVED 1
, MOA of Acamprosate - Correct answer-- weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
MOA of Disulfuram - Correct answer-inhibits enzyme (aldehyde dehydrogenase)
in the liver
Bupropions role in alcohol use disorder - Correct answer-Can diminish cravings
for etoh, treat underlying anxiety/depression
Safety Risk associated with bupropion and etoh - Correct answer-bupropion
increases the risk of seizures in those going through etoh withdrawal
s/s ETOH intoxication - Correct answer-impaired fine motor control, impaired
judgement and coordination, ataxic gait, poor balance, lethargy, difficulty sitting
upright, difficulty with memory and sitting upright, N/V, coma in levels 300mg/dL
and over with respiratory depression and death possible
S/S of etoh withdrawal - Correct answer-Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
©COPYRIGHT 2025, ALL RIGHTS RESERVED 2
