MN 553 UNIT 10 FINAL EXAM PHARMACOLOGY: PURDUE
UNIVERSITY QUESTIONS WITH COMPLETE SOLUTIONS
GUARANTEED PASS BRAND NEW 2025/2026
Question 8
A provider may consider testing for CYP2D6 variants prior to starting
tamoxifen for breast cancer to:
Question options:
Ensure the patient will not have increased adverse drug reactions to the
tamoxifen
Identify potential drug-drug interactions that may occur with tamoxifen
Reduce the likelihood of therapeutic failure with tamoxifen treatment
9 Identify poor metabolizers of tamoxifen Question
Several classes of drugs have interactions with cholinergic blockers.
Which of the following is true about these interactions?
Question options:
Drugs with a narrow therapeutic range given orally may not stay in the GI tract
long enough to
prod
Additive antimuscarinic effects may occur with antihistamines.
, Cholinergic blockers may decrease the sedative effects of hypnotics.
10 Cholinergic blockers are contraindicated with antipsychotics. Question
Absolute contraindications that clinicians must consider when initiating
estrogen therapy include:
Question options:
Undiagnosed dysfunctional uterine bleeding
Deep vein or arterial thromboemboli within the prior year
Endometriosis
Both a. and b.
11 All of the above Question
First-line therapy for treating topical fungal infections such as tinea
corporis (ringworm) or tinea pedis (athlete’s foot) would be:
Question options:
OTC topical azole (clotrimazole, miconazole)
Oral terbinafine
Oral griseofulvin microsize
Nystatin cream or ointment
Question 12
Preventative therapy for cluster headaches includes:
,Question options:
Massage or relaxation therapy
Ergotamine nightly before bed
Intranasal lidocaine four times a day during “clusters” of headaches
Propranolol (Inderal) daily
Question 13
Why is the consistency of taking paroxetine (Paxil) and never running
out of medication more important than with most other selective
serotonin reuptake inhibitors (SSRIs)?
Question options:
It has a shorter half-life and withdrawal syndrome has a faster onset withou
taper.
It has the longest half-life and the withdrawal syndrome has a faster
onset.
It is quasi-addictive in the dopaminergic reward system.
It is the most activating of SSRI medications and will cause the person to
have sudden deep sadness
Question 14
Sook has been prescribed gabapentin to treat neuropathic pain and is
complaining of feeling depressed and having “strange” thoughts. The
appropriate initial action would be: Question options:
Increase her dose
Assess for suicidal ideation
, Discontinue the medication immediately
15 Decrease her dose to half then slowly titrate up the dose Question
The drug of choice for type 2 diabetics is metformin. Metformin:
Question options:
Decreases glycogenolysis by the liver
Increases the release of insulin from beta cells
Increases intestinal uptake of glucose
16 Prevents weight gain associated with hyperglycemia Question
Gender differences between men and women in pharmacokinetics
include: Question options:
More rapid gastric emptying so that drugs absorbed in the stomach hav
less exposure to absorption
Higher proportion of body fat so that lipophilic drugs have relatively
greater volumes of
distribution
Increased levels of bile acids so that drugs metabolized in the intestine
have higher concentrations
Slower organ blood flow rates so drugs tend to take longer to be
excreted
UNIVERSITY QUESTIONS WITH COMPLETE SOLUTIONS
GUARANTEED PASS BRAND NEW 2025/2026
Question 8
A provider may consider testing for CYP2D6 variants prior to starting
tamoxifen for breast cancer to:
Question options:
Ensure the patient will not have increased adverse drug reactions to the
tamoxifen
Identify potential drug-drug interactions that may occur with tamoxifen
Reduce the likelihood of therapeutic failure with tamoxifen treatment
9 Identify poor metabolizers of tamoxifen Question
Several classes of drugs have interactions with cholinergic blockers.
Which of the following is true about these interactions?
Question options:
Drugs with a narrow therapeutic range given orally may not stay in the GI tract
long enough to
prod
Additive antimuscarinic effects may occur with antihistamines.
, Cholinergic blockers may decrease the sedative effects of hypnotics.
10 Cholinergic blockers are contraindicated with antipsychotics. Question
Absolute contraindications that clinicians must consider when initiating
estrogen therapy include:
Question options:
Undiagnosed dysfunctional uterine bleeding
Deep vein or arterial thromboemboli within the prior year
Endometriosis
Both a. and b.
11 All of the above Question
First-line therapy for treating topical fungal infections such as tinea
corporis (ringworm) or tinea pedis (athlete’s foot) would be:
Question options:
OTC topical azole (clotrimazole, miconazole)
Oral terbinafine
Oral griseofulvin microsize
Nystatin cream or ointment
Question 12
Preventative therapy for cluster headaches includes:
,Question options:
Massage or relaxation therapy
Ergotamine nightly before bed
Intranasal lidocaine four times a day during “clusters” of headaches
Propranolol (Inderal) daily
Question 13
Why is the consistency of taking paroxetine (Paxil) and never running
out of medication more important than with most other selective
serotonin reuptake inhibitors (SSRIs)?
Question options:
It has a shorter half-life and withdrawal syndrome has a faster onset withou
taper.
It has the longest half-life and the withdrawal syndrome has a faster
onset.
It is quasi-addictive in the dopaminergic reward system.
It is the most activating of SSRI medications and will cause the person to
have sudden deep sadness
Question 14
Sook has been prescribed gabapentin to treat neuropathic pain and is
complaining of feeling depressed and having “strange” thoughts. The
appropriate initial action would be: Question options:
Increase her dose
Assess for suicidal ideation
, Discontinue the medication immediately
15 Decrease her dose to half then slowly titrate up the dose Question
The drug of choice for type 2 diabetics is metformin. Metformin:
Question options:
Decreases glycogenolysis by the liver
Increases the release of insulin from beta cells
Increases intestinal uptake of glucose
16 Prevents weight gain associated with hyperglycemia Question
Gender differences between men and women in pharmacokinetics
include: Question options:
More rapid gastric emptying so that drugs absorbed in the stomach hav
less exposure to absorption
Higher proportion of body fat so that lipophilic drugs have relatively
greater volumes of
distribution
Increased levels of bile acids so that drugs metabolized in the intestine
have higher concentrations
Slower organ blood flow rates so drugs tend to take longer to be
excreted
