NR 507 midterm
Study online at https://quizlet.com/_9byg4l
1. Hypersensitivity: Type 1: -Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
2. Hypersensitivity: Type 2: -Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
3. Hypersensitivity 2: -Graves Disease (hyperthyroidism) -alters function not destroy
-blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis
-drug allergies
-hemolytic anemia
4. Hypersensitivity: type 3: -Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the blood or bodily fluids, and
the complex is then deposited in the tissues
5. Hypersensitivity: Type 3: -rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
6. Hives (urticaria): Hypersensitivity Type 1
7. First responders to innate the immune system: Neutrophils
8. Allergic contact dermatitis: Hypersensitivity Type IV
9. Type 2 cytotoxic hypersensitivity mediated by:: -IgG IgM
-macrophages are primary effort cells
-
10. Serum Sickness: type 3 hypersensitivity
11. Hypersensitivity IV,: -is more of a delayed immune response.
-mediated T-cells attack tissue directly (no antibodies)
12. Autoimmune: -diseases in which the body makes antibodies directed against its own tissues
-
13. Primary immunodeficiency: -Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
, NR 507 midterm
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14. secondary immunodeficiency: -acquired
15. Common cause of secondary immunodeficiency: Malnutrition
16. Most patients diagnosed with SLE will have a positive ?: antinuclear antibody (ANA)
17. SLE (lupus): -Facial rash
-vasculitis
- tissue inflammation
18. Renal disease associated with autoimmunity?: Glomerulonephritis
19. Sjogren's syndrome: Inflammation in salivary and lacrimal glands
20. SLE: Autoantibodies and auto-active t-cells against DNA and nucleoprotein
21. Sjögren's syndrome immune changes:: Autoantibodies and auto-reactive t-cells against apop-
totic cells
22. rheumatoid arthritis manifestations:: Joint inflammation, stiffness, pain, loss of range of motion
23. Rheumatoid Arthritis immune changes:: T-cells and B cells against joint associated antigens
24. MS manifestations: Formation of sclerotic plaque in the brain, leads to Muscle weakness and ataxia
25. MS immune changes: T-cells against brain antigens
26. ___ measures the average size of RBCs: MCV
27. Anemia occur by...: -impaired RBC production
-excessive blood loss
- increased RBC production
28. microlytic anemia is characterized by hyper chromic RBS:: Hereditary spherocytosis
29. Anemia: -"without blood"
30. 4.7-6.1mcl: Normal for men RBC
31. 4.5-5.2mcL: Normal for women RBC
32. 13.5-17.5: Normal hemoglobin for men
33. 12.0-15.5 g/dL: Normal hemoglobin for women
34. RBC: The number of erythrocytes in 1 cubic mm of whole blood
35. Hemoglobin (Hgb): The oxygen-carrying pigment of red cells
36. Hematocrit (Hct): The volume of cells as a % of total volume of cells and plasma in whole blood
37. 42-45%: Normal for HCT for men
38. 37-48%: Normal HCT for women
39. Mean Cell Volume (MCV): Measures the average size of the RBC
40. 80-100 fL: Normal MCV
Study online at https://quizlet.com/_9byg4l
1. Hypersensitivity: Type 1: -Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
2. Hypersensitivity: Type 2: -Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
3. Hypersensitivity 2: -Graves Disease (hyperthyroidism) -alters function not destroy
-blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis
-drug allergies
-hemolytic anemia
4. Hypersensitivity: type 3: -Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the blood or bodily fluids, and
the complex is then deposited in the tissues
5. Hypersensitivity: Type 3: -rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
6. Hives (urticaria): Hypersensitivity Type 1
7. First responders to innate the immune system: Neutrophils
8. Allergic contact dermatitis: Hypersensitivity Type IV
9. Type 2 cytotoxic hypersensitivity mediated by:: -IgG IgM
-macrophages are primary effort cells
-
10. Serum Sickness: type 3 hypersensitivity
11. Hypersensitivity IV,: -is more of a delayed immune response.
-mediated T-cells attack tissue directly (no antibodies)
12. Autoimmune: -diseases in which the body makes antibodies directed against its own tissues
-
13. Primary immunodeficiency: -Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
, NR 507 midterm
Study online at https://quizlet.com/_9byg4l
14. secondary immunodeficiency: -acquired
15. Common cause of secondary immunodeficiency: Malnutrition
16. Most patients diagnosed with SLE will have a positive ?: antinuclear antibody (ANA)
17. SLE (lupus): -Facial rash
-vasculitis
- tissue inflammation
18. Renal disease associated with autoimmunity?: Glomerulonephritis
19. Sjogren's syndrome: Inflammation in salivary and lacrimal glands
20. SLE: Autoantibodies and auto-active t-cells against DNA and nucleoprotein
21. Sjögren's syndrome immune changes:: Autoantibodies and auto-reactive t-cells against apop-
totic cells
22. rheumatoid arthritis manifestations:: Joint inflammation, stiffness, pain, loss of range of motion
23. Rheumatoid Arthritis immune changes:: T-cells and B cells against joint associated antigens
24. MS manifestations: Formation of sclerotic plaque in the brain, leads to Muscle weakness and ataxia
25. MS immune changes: T-cells against brain antigens
26. ___ measures the average size of RBCs: MCV
27. Anemia occur by...: -impaired RBC production
-excessive blood loss
- increased RBC production
28. microlytic anemia is characterized by hyper chromic RBS:: Hereditary spherocytosis
29. Anemia: -"without blood"
30. 4.7-6.1mcl: Normal for men RBC
31. 4.5-5.2mcL: Normal for women RBC
32. 13.5-17.5: Normal hemoglobin for men
33. 12.0-15.5 g/dL: Normal hemoglobin for women
34. RBC: The number of erythrocytes in 1 cubic mm of whole blood
35. Hemoglobin (Hgb): The oxygen-carrying pigment of red cells
36. Hematocrit (Hct): The volume of cells as a % of total volume of cells and plasma in whole blood
37. 42-45%: Normal for HCT for men
38. 37-48%: Normal HCT for women
39. Mean Cell Volume (MCV): Measures the average size of the RBC
40. 80-100 fL: Normal MCV
