NR 603 WEEK 1 |2025| COMPLETE
EXAM TEST QUESTIONS AND
VERIFIED ANSWERS (MULTIPLE
CHOICES),100% ACCURATE!!
AA275-year-
oldA2manA2isA2involvedA2inA2aA2motorA2vehicleA2accidentA2andA2strikesA2hisA2foreheadA2onA
2theA2windshield.A2HeA2complainsA2ofA2neckA2painA2andA2severeA2burningA2inA2hisA2should
ersA2andA2arms.A2HisA2physicalA2examinationA2revealsA2weaknessA2ofA2hisA2upperA2extre
mities.A2WhatA2typeA2ofA2spinalA2cordA2injuryA2doesA2thisA2patientA2have?
AA2anteriorA2cordA2syndromeA2
BA2centralA2cordA2syndromeA2
CA2Brown-SéquardA2syndromeA2
DA2completeA2cordA2transectionA2
EA2caudaA2equinaA2syndrome
ANS:A2BA2-A2Ans--CentralA2CordA2Syndrome
theA2centralA2cordA2syndromeA2involvesA2lossA2ofA2motorA2functionA2thatA2isA2moreA2sever
eA2inA2theA2upperA2extremitiesA2thanA2inA2theA2lowerA2extremities,A2andA2isA2moreA2severe
A2inA2theA2hands.A2ThereA2isA2typicallyA2hyperesthesiaA2overA2theA2shouldersA2andA2arms.
A2AnteriorA2cordA2syndromeA2presentsA2withA2paraplegiaA2orA2quadriplegia,A2lossA2ofA2late
ralA2spinothalamicA2functionA2withA2preservationA2ofA2posteriorA2columnA2function.A2Brown
-
SéquardA2syndromeA2consistsA2ofA2weaknessA2andA2lossA2ofA2posteriorA2columnA2functio
nA2onA2oneA2sideA2ofA2theA2bodyA2distalA2toA2theA2lesionA2withA2contralateralA2lossA2ofA2late
ralA2spinothalamicA2functionA2oneA2toA2twoA2levelsA2belowA2theA2lesion.A2CompleteA2cordA
2transectionA2wouldA2affectA2motorA2andA2sensoryA2functionA2distalA2toA2theA2lesion.A2Cau
daA2equinaA2syndromeA2typicallyA2presentsA2asA2lowA2backA2painA2withA2radiculopathy.
AA237-year-
oldA2manA2fellA2fromA2aA2ladderA2asA2heA2finishedA2hangingA2theA2ChristmasA2lightsA2onA2h
isA2house.A2TheA2rightA2sideA2ofA2hisA2headA2hitA2theA2alleyA2cement,A2andA2heA2lostA2cons
ciousnessA2forA2aboutA21A2minute;A2heA2wokeA2upA2withA2aA2headache,A2butA2heA2hadA2no
A2otherA2complaints.A2AA2fewA2hoursA2later,A2theA2patientA2isA2broughtA2toA2theA2emergenc
yA2roomA2byA2hisA2neighborA2becauseA2ofA2anA2intenseA2headache,A2confusion,A2andA2left
A2handA2hemiparesis.A2OnA2examination,A2theA2patientA2hasA2aA2bruiseA2locatedA2overA2th
eA2rightA2temporalA2region,A2mydriasis,A2andA2rightA2deviationA2ofA2theA2rightA2eye,A2papill
edema,A2andA2leftA2extensorA2plantarA2response.A2AnA2emergencyA2CTA2scanA2ofA2theA2h
eadA2withoutA2contrastA2revealsA2aA2lens-shapedA2hyper-
densityA2underA2theA2rightA2temporalA2boneA2withA2massA2effectA2andA2edema.A2WhatA2isA
2theA2mostA2likelyA2diagnosis?
,AnswerA2Choices
1A2EpiduralA2hematoma
2A2SubduralA2hematoma
3A2SubarachnoidA2hemorrhage
4A2IntracerebralA2parenchymalA2hemorrhage
5A2AcuteA2meningitis
ANS:A21A2-A2Ans--EpiduralA2Hematoma
EpiduralA2hematomaA2mostA2oftenA2resultsA2fromA2aA2traumaticA2tearA2ofA2theA2middleA2m
eningealA2artery.A2AlthoughA2aA2lucidA2intervalA2rangingA2fromA2minutesA2toA2hoursA2follow
edA2byA2alteredA2mentalA2statusA2andA2focalA2deficitsA2isA2typicalA2forA2epiduralA2hematom
a,A2thisA2clinicalA2pictureA2isA2onlyA2encounteredA2inA2upA2toA21/3A2ofA2theA2patients.A2TheA
2collectionA2ofA2bloodA2betweenA2theA2skullA2andA2duraA2materA2causesA2anA2evidentA2ma
ssA2effectA2withA2ophthalmicA2nerveA2palsyA2andA2theA2contralateralA2hemiparesis.A2Surgi
calA2evacuationA2ofA2theA2clotA2viaA2burrA2holesA2isA2theA2treatmentA2ofA2choice.
SubduralA2hematomaA2resultsA2fromA2aA2traumaticA2ruptureA2ofA2theA2bridgingA2veinsA2tha
tA2connectA2theA2cerebrumA2toA2theA2venousA2sinusesA2withinA2theA2dura.A2ThisA2venousA2
hemorrhageA2willA2resultA2inA2aA2gradualA2increaseA2ofA2theA2hematoma,A2withA2aA2progre
ssiveA2clinicalA2pictureA2overA2daysA2orA2weeks.A2TheA2CTA2scanA2willA2showA2aA2concave
,A2crescent-shapedA2hyper-densityA2comparedA2toA2theA2convex,A2lens-shapedA2hyper-
densityA2inA2epiduralA2hematoma.
SubarachnoidA2hemorrhageA2isA2theA2resultA2ofA2anA2aneurysmA2rupture;A2theA2mostA2co
mmonA2isA2theA2congenitalA2berryA2aneurysm.A2TheA2clinicalA2pictureA2isA2ofA2aA2sudden,A
2severeA2headacheA2withA2meningealA2irritation.A2AA2CTA2scanA2willA2showA2bloodA2inA2the
A2subarachnoidA2space,A2andA2aA2lumbarA2punctureA2willA2revealA2xanthochromiaA2CSF.
IntracerebralA2parenchymalA2hemorrhageA2isA2mostA2likelyA2causedA2byA2hypertensionA2c
omplicatedA2withA2Charcot-
BouchardA2aneurysms.A2TheA2bloodA2accumulatesA2intoA2theA2brainA2substanceA2andA2m
ostA2commonlyA2involvesA2theA2basalA2ganglia.
AcuteA2meningitisA2isA2notA2associatedA2withA2trauma.A2FeverA2andA2signsA2ofA2meningeal
A2irritationA2dominateA2theA2clinicalA2picture.A2LumbarA2puncture,A2indicatedA2ifA2thereA2are
A2noA2focalA2neurologicalA2signsA2onA2clinicalA2examination,A2willA2beA2theA2diagnosticA2pr
ocedure.A2TheA2CTA2scanA2ofA2theA2patientA2presentedA2inA2thisA2caseA2isA2characteristicA
2forA2epiduralA2hematoma,A2andA2thereA2isA2noA2indicationA2forA2aA2lumbarA2punctu
AA231-year-
oldA2womanA2presentsA2withA2aA2purpuralA2rashA2coveringA2herA2arms,A2legs,A2andA2abdo
men.A2SheA2alsoA2hasA2fever,A2chills,A2nausea,A2abdominalA2tenderness,A2tachycardia,A2a
ndA2generalizedA2myalgias.A2PriorA2toA2theA2developmentA2ofA2theA2rash,A2theA2patientA2n
otedA2thatA2sheA2hadA2aA2headache,A2cough,A2andA2soreA2throat.A2LaboratoryA2studiesA2w
ereA2positiveA2forA2Gram-
negativeA2diplococciA2inA2theA2blood,A2alongA2withA2thrombocytopeniaA2andA2anA2elevatio
nA2inA2PMNs.A2UrinalysisA2showedA2blood,A2protein,A2andA2casts.A2VitalA2signsA2areA2asA2f
,ollows:A2PBA292/66,A2PA296,A2RRA214,A2TA239.A2TheA2patientA2deniesA2anyA2foreignA2travel
A2andA2doesA2notA2haveA2anyA2sickA2contacts.A2However,A2sheA2doesA2workA2partA2timeA2
asA2aA2nurseA2inA2aA2localA2hospital.
QuestionA2
TheA2patientA2isA2diagnosedA2withA2Meningococcemia;A2sheA2isA2admittedA2toA2theA2hospi
talA2andA2placedA2inA2respiratoryA2isolation.A2WhatA2majorA2courseA2ofA2therapyA2shouldA2t
hisA2patientA2receive?
AnswerA2Choices
1A2Steroids
2A2SupportiveA2care
3A2Antibiotics
4A2Transfusion
5A2BactericiA2-A2Ans--Antibiotics
AntibioticsA2areA2theA2treatmentA2ofA2choiceA2forA2meningococcemia.A2TheA2preferredA2dr
ugA2forA2activeA2infectionA2isA2penicillinA2G.A2ForA2thoseA2allergicA2toA2penicillin,A2chloramp
henicolA2andA2cephalosporinsA2(ie,A2cefotaxime,A2cefuroxime)A2mayA2beA2usedA2asA2alter
natives.
PatientsA2willA2alsoA2receiveA2supportiveA2care,A2butA2antibioticA2therapyA2mustA2beA2initia
tedA2quicklyA2ifA2theA2patientA2isA2toA2survive.A2IntensiveA2careA2placementA2mayA2beA2nec
essaryA2ifA2organA2failureA2isA2imminent.A2VentilatoryA2support,A2inotropicA2support,A2andA
2IVA2fluidsA2areA2necessaryA2inA2some.A2IfA2adrenalA2insufficiencyA2occurs,A2corticosteroid
A2replacementA2mayA2beA2considered.A2AA2centralA2venousA2lineA2helpsA2toA2provideA2larg
eA2amountsA2ofA2volumeA2expandersA2andA2inotropicA2medicationsA2forA2adequateA2tissue
A2perfusion.
SteroidsA2haveA2notA2beenA2shownA2toA2playA2aA2majorA2roleA2inA2theA2treatmentA2ofA2men
ingococcemia.A2However,A2theyA2haveA2beenA2usedA2inA2additionA2toA2antibioticA2therapy.
A2InA2theA2caseA2ofA2adrenalA2insufficiency,A2forA2example,A2steroidA2replacementA2hasA2b
eenA2shownA2toA2beA2beneficial.
TransfusionA2doesA2notA2generallyA2playA2aA2majorA2roleA2inA2treatment.A2IfA2theA2patientA2
suffersA2fromA2aA2devastatingA2coagulopathy,A2bloodA2orA2bloodA2productsA2mayA2beA2rep
lacedA2asA2necessary.
Bactericidal/permeability-
increasingA2proteinA2isA2aA2proteinA2storedA2inA2theA2granulesA2ofA2neutrophils.A2ItA2bindsA2
toA2endotoxinA2inA2vitroA2andA2neutralizesA2it.A2ThisA2techniqueA2isA2experimental,A2andA2it
A2isA2notA2usedA2inA2everydayA2treatmentA2ofA2meningococcemia.
InA2myastheniaA2gravis,A2weaknessA2isA2aA2resultA2ofA2insufficientA2acetylcholineA2transmi
ssionA2atA2theA2neuromuscularA2junction;A2however,A2weaknessA2canA2alsoA2occurA2withA2
overdosingA2ofA2theA2cholinergicA2medicationsA2usedA2toA2treatA2myasthenia.A2WhatA2sym
ptomA2helpsA2differentiateA2aA2myasthenicA2crisisA2fromA2aA2cholinergicA2crisis?
, AnswerA2Choices
1A2RespiratoryA2failure
2A2BilateralA2ptosis
3A2MuscleA2fasciculations
4A2Diplopia
5A2NormalA2muscleA2stretchA2reflexes
ANS:A23A2-A2Ans--MuscleA2Fasiculations
SignsA2ofA2cholinergicA2overdosageA2includeA2muscleA2fasciculation,A2rhinorrhea,A2lacrim
ation,A2salivation,A2increasedA2bronchialA2secretions,A2nausea,A2orA2diarrhea.A2TheA2pres
enceA2ofA2anyA2ofA2theseA2suggestsA2thatA2theA2patient'sA2weaknessA2mayA2beA2dueA2toA2
cholinergicA2crisis.A2TheA2otherA2signsA2areA2dueA2toA2weaknessA2andA2canA2occurA2inA2eit
herA2condition.
AA254-year-
oldA2manA2presentsA2afterA2havingA2aA2generalizedA2seizure.A2TheA2patientA2isA2HIVA2posi
tive,A2butA2heA2hasA2beenA2unableA2toA2affordA2antiretroviralA2therapyA2sinceA2losingA2hisA2
jobA22A2yearsA2ago.A2OtherA2thanA2cachexia,A2theA2physicalA2examA2isA2unremarkable.A2U
ponA2furtherA2inquiry,A2theA2patientA2alsoA2notesA2thatA2heA2hasA2becomeA2short-
temperedA2andA2hypercritical;A2atA2times,A2heA2seemsA2confused.A2AnA2MRIA2ofA2theA2brai
nA2isA2performed,A2andA2itA2revealsA2severalA2corticalA2ring-enhancingA2lesions.
QuestionA2
WhatA2isA2theA2mostA2likelyA2diagnosis?
AnswerA2Choices
1A2AIDSA2dementiaA2complex
2A2CryptococcalA2meningitis
3A2CytomegalovirusA2encephalitis
4A2ProgressiveA2multifocalA2leukoencephalopathy
5A2ToxoplasmaA2encephalitis
ANS:5A2-A2Ans--ToxoplasmaA2encephalitis
TheA2patient'sA2symptomsA2andA2MRIA2findingsA2areA2mostA2consistentA2withA2theA2diagn
osisA2ofA2toxoplasmaA2encephalitis.A2ToxoplasmosisA2isA2theA2mostA2commonA2cerebralA2
massA2lesionA2amongA2HIV-
positiveA2patients.A2InfectionA2withA2theA2ToxoplasmaA2gondiiA2parasiteA2isA2relativelyA2co
mmonA2andA2usuallyA2asymptomatic.A2ReactivationA2occursA2inA2HIVA2positiveA2patientsA2
dueA2toA2failingA2cellularA2immunity,A2andA2itA2causesA2aA2multifocalA2necrotizingA2enceph
alitis.A2SeizuresA2mayA2beA2theA2initialA2manifestationA2ofA2centralA2nervousA2systemA2(CN
S)A2infection;A2otherA2commonA2clinicalA2manifestationsA2includeA2focalA2neurologicA2defic
its,A2suchA2asA2impairedA2speechA2andA2hemiparesis.A2PersonalityA2change,A2lethargy,A2h
eadache,A2andA2confusionA2areA2alsoA2observed.A2TheA2MRIA2inA2patientsA2withA2toxoplas
maA2encephalitisA2characteristicallyA2revealsA2multiple,A2ring-
enhancingA2lesionsA2withA2surroundingA2edema;A2theseA2lesionsA2usuallyA2occurA2bilatera
llyA2inA2theA2frontalA2andA2parietalA2cortices.
AIDSA2dementiaA2complexA2describesA2aA2constellationA2ofA2cognitiveA2symptomsA2seenA
2amongA2HIVA2positiveA2patients.A2TheA2conditionA2occursA2whenA2HIVA2virusA2disseminat
EXAM TEST QUESTIONS AND
VERIFIED ANSWERS (MULTIPLE
CHOICES),100% ACCURATE!!
AA275-year-
oldA2manA2isA2involvedA2inA2aA2motorA2vehicleA2accidentA2andA2strikesA2hisA2foreheadA2onA
2theA2windshield.A2HeA2complainsA2ofA2neckA2painA2andA2severeA2burningA2inA2hisA2should
ersA2andA2arms.A2HisA2physicalA2examinationA2revealsA2weaknessA2ofA2hisA2upperA2extre
mities.A2WhatA2typeA2ofA2spinalA2cordA2injuryA2doesA2thisA2patientA2have?
AA2anteriorA2cordA2syndromeA2
BA2centralA2cordA2syndromeA2
CA2Brown-SéquardA2syndromeA2
DA2completeA2cordA2transectionA2
EA2caudaA2equinaA2syndrome
ANS:A2BA2-A2Ans--CentralA2CordA2Syndrome
theA2centralA2cordA2syndromeA2involvesA2lossA2ofA2motorA2functionA2thatA2isA2moreA2sever
eA2inA2theA2upperA2extremitiesA2thanA2inA2theA2lowerA2extremities,A2andA2isA2moreA2severe
A2inA2theA2hands.A2ThereA2isA2typicallyA2hyperesthesiaA2overA2theA2shouldersA2andA2arms.
A2AnteriorA2cordA2syndromeA2presentsA2withA2paraplegiaA2orA2quadriplegia,A2lossA2ofA2late
ralA2spinothalamicA2functionA2withA2preservationA2ofA2posteriorA2columnA2function.A2Brown
-
SéquardA2syndromeA2consistsA2ofA2weaknessA2andA2lossA2ofA2posteriorA2columnA2functio
nA2onA2oneA2sideA2ofA2theA2bodyA2distalA2toA2theA2lesionA2withA2contralateralA2lossA2ofA2late
ralA2spinothalamicA2functionA2oneA2toA2twoA2levelsA2belowA2theA2lesion.A2CompleteA2cordA
2transectionA2wouldA2affectA2motorA2andA2sensoryA2functionA2distalA2toA2theA2lesion.A2Cau
daA2equinaA2syndromeA2typicallyA2presentsA2asA2lowA2backA2painA2withA2radiculopathy.
AA237-year-
oldA2manA2fellA2fromA2aA2ladderA2asA2heA2finishedA2hangingA2theA2ChristmasA2lightsA2onA2h
isA2house.A2TheA2rightA2sideA2ofA2hisA2headA2hitA2theA2alleyA2cement,A2andA2heA2lostA2cons
ciousnessA2forA2aboutA21A2minute;A2heA2wokeA2upA2withA2aA2headache,A2butA2heA2hadA2no
A2otherA2complaints.A2AA2fewA2hoursA2later,A2theA2patientA2isA2broughtA2toA2theA2emergenc
yA2roomA2byA2hisA2neighborA2becauseA2ofA2anA2intenseA2headache,A2confusion,A2andA2left
A2handA2hemiparesis.A2OnA2examination,A2theA2patientA2hasA2aA2bruiseA2locatedA2overA2th
eA2rightA2temporalA2region,A2mydriasis,A2andA2rightA2deviationA2ofA2theA2rightA2eye,A2papill
edema,A2andA2leftA2extensorA2plantarA2response.A2AnA2emergencyA2CTA2scanA2ofA2theA2h
eadA2withoutA2contrastA2revealsA2aA2lens-shapedA2hyper-
densityA2underA2theA2rightA2temporalA2boneA2withA2massA2effectA2andA2edema.A2WhatA2isA
2theA2mostA2likelyA2diagnosis?
,AnswerA2Choices
1A2EpiduralA2hematoma
2A2SubduralA2hematoma
3A2SubarachnoidA2hemorrhage
4A2IntracerebralA2parenchymalA2hemorrhage
5A2AcuteA2meningitis
ANS:A21A2-A2Ans--EpiduralA2Hematoma
EpiduralA2hematomaA2mostA2oftenA2resultsA2fromA2aA2traumaticA2tearA2ofA2theA2middleA2m
eningealA2artery.A2AlthoughA2aA2lucidA2intervalA2rangingA2fromA2minutesA2toA2hoursA2follow
edA2byA2alteredA2mentalA2statusA2andA2focalA2deficitsA2isA2typicalA2forA2epiduralA2hematom
a,A2thisA2clinicalA2pictureA2isA2onlyA2encounteredA2inA2upA2toA21/3A2ofA2theA2patients.A2TheA
2collectionA2ofA2bloodA2betweenA2theA2skullA2andA2duraA2materA2causesA2anA2evidentA2ma
ssA2effectA2withA2ophthalmicA2nerveA2palsyA2andA2theA2contralateralA2hemiparesis.A2Surgi
calA2evacuationA2ofA2theA2clotA2viaA2burrA2holesA2isA2theA2treatmentA2ofA2choice.
SubduralA2hematomaA2resultsA2fromA2aA2traumaticA2ruptureA2ofA2theA2bridgingA2veinsA2tha
tA2connectA2theA2cerebrumA2toA2theA2venousA2sinusesA2withinA2theA2dura.A2ThisA2venousA2
hemorrhageA2willA2resultA2inA2aA2gradualA2increaseA2ofA2theA2hematoma,A2withA2aA2progre
ssiveA2clinicalA2pictureA2overA2daysA2orA2weeks.A2TheA2CTA2scanA2willA2showA2aA2concave
,A2crescent-shapedA2hyper-densityA2comparedA2toA2theA2convex,A2lens-shapedA2hyper-
densityA2inA2epiduralA2hematoma.
SubarachnoidA2hemorrhageA2isA2theA2resultA2ofA2anA2aneurysmA2rupture;A2theA2mostA2co
mmonA2isA2theA2congenitalA2berryA2aneurysm.A2TheA2clinicalA2pictureA2isA2ofA2aA2sudden,A
2severeA2headacheA2withA2meningealA2irritation.A2AA2CTA2scanA2willA2showA2bloodA2inA2the
A2subarachnoidA2space,A2andA2aA2lumbarA2punctureA2willA2revealA2xanthochromiaA2CSF.
IntracerebralA2parenchymalA2hemorrhageA2isA2mostA2likelyA2causedA2byA2hypertensionA2c
omplicatedA2withA2Charcot-
BouchardA2aneurysms.A2TheA2bloodA2accumulatesA2intoA2theA2brainA2substanceA2andA2m
ostA2commonlyA2involvesA2theA2basalA2ganglia.
AcuteA2meningitisA2isA2notA2associatedA2withA2trauma.A2FeverA2andA2signsA2ofA2meningeal
A2irritationA2dominateA2theA2clinicalA2picture.A2LumbarA2puncture,A2indicatedA2ifA2thereA2are
A2noA2focalA2neurologicalA2signsA2onA2clinicalA2examination,A2willA2beA2theA2diagnosticA2pr
ocedure.A2TheA2CTA2scanA2ofA2theA2patientA2presentedA2inA2thisA2caseA2isA2characteristicA
2forA2epiduralA2hematoma,A2andA2thereA2isA2noA2indicationA2forA2aA2lumbarA2punctu
AA231-year-
oldA2womanA2presentsA2withA2aA2purpuralA2rashA2coveringA2herA2arms,A2legs,A2andA2abdo
men.A2SheA2alsoA2hasA2fever,A2chills,A2nausea,A2abdominalA2tenderness,A2tachycardia,A2a
ndA2generalizedA2myalgias.A2PriorA2toA2theA2developmentA2ofA2theA2rash,A2theA2patientA2n
otedA2thatA2sheA2hadA2aA2headache,A2cough,A2andA2soreA2throat.A2LaboratoryA2studiesA2w
ereA2positiveA2forA2Gram-
negativeA2diplococciA2inA2theA2blood,A2alongA2withA2thrombocytopeniaA2andA2anA2elevatio
nA2inA2PMNs.A2UrinalysisA2showedA2blood,A2protein,A2andA2casts.A2VitalA2signsA2areA2asA2f
,ollows:A2PBA292/66,A2PA296,A2RRA214,A2TA239.A2TheA2patientA2deniesA2anyA2foreignA2travel
A2andA2doesA2notA2haveA2anyA2sickA2contacts.A2However,A2sheA2doesA2workA2partA2timeA2
asA2aA2nurseA2inA2aA2localA2hospital.
QuestionA2
TheA2patientA2isA2diagnosedA2withA2Meningococcemia;A2sheA2isA2admittedA2toA2theA2hospi
talA2andA2placedA2inA2respiratoryA2isolation.A2WhatA2majorA2courseA2ofA2therapyA2shouldA2t
hisA2patientA2receive?
AnswerA2Choices
1A2Steroids
2A2SupportiveA2care
3A2Antibiotics
4A2Transfusion
5A2BactericiA2-A2Ans--Antibiotics
AntibioticsA2areA2theA2treatmentA2ofA2choiceA2forA2meningococcemia.A2TheA2preferredA2dr
ugA2forA2activeA2infectionA2isA2penicillinA2G.A2ForA2thoseA2allergicA2toA2penicillin,A2chloramp
henicolA2andA2cephalosporinsA2(ie,A2cefotaxime,A2cefuroxime)A2mayA2beA2usedA2asA2alter
natives.
PatientsA2willA2alsoA2receiveA2supportiveA2care,A2butA2antibioticA2therapyA2mustA2beA2initia
tedA2quicklyA2ifA2theA2patientA2isA2toA2survive.A2IntensiveA2careA2placementA2mayA2beA2nec
essaryA2ifA2organA2failureA2isA2imminent.A2VentilatoryA2support,A2inotropicA2support,A2andA
2IVA2fluidsA2areA2necessaryA2inA2some.A2IfA2adrenalA2insufficiencyA2occurs,A2corticosteroid
A2replacementA2mayA2beA2considered.A2AA2centralA2venousA2lineA2helpsA2toA2provideA2larg
eA2amountsA2ofA2volumeA2expandersA2andA2inotropicA2medicationsA2forA2adequateA2tissue
A2perfusion.
SteroidsA2haveA2notA2beenA2shownA2toA2playA2aA2majorA2roleA2inA2theA2treatmentA2ofA2men
ingococcemia.A2However,A2theyA2haveA2beenA2usedA2inA2additionA2toA2antibioticA2therapy.
A2InA2theA2caseA2ofA2adrenalA2insufficiency,A2forA2example,A2steroidA2replacementA2hasA2b
eenA2shownA2toA2beA2beneficial.
TransfusionA2doesA2notA2generallyA2playA2aA2majorA2roleA2inA2treatment.A2IfA2theA2patientA2
suffersA2fromA2aA2devastatingA2coagulopathy,A2bloodA2orA2bloodA2productsA2mayA2beA2rep
lacedA2asA2necessary.
Bactericidal/permeability-
increasingA2proteinA2isA2aA2proteinA2storedA2inA2theA2granulesA2ofA2neutrophils.A2ItA2bindsA2
toA2endotoxinA2inA2vitroA2andA2neutralizesA2it.A2ThisA2techniqueA2isA2experimental,A2andA2it
A2isA2notA2usedA2inA2everydayA2treatmentA2ofA2meningococcemia.
InA2myastheniaA2gravis,A2weaknessA2isA2aA2resultA2ofA2insufficientA2acetylcholineA2transmi
ssionA2atA2theA2neuromuscularA2junction;A2however,A2weaknessA2canA2alsoA2occurA2withA2
overdosingA2ofA2theA2cholinergicA2medicationsA2usedA2toA2treatA2myasthenia.A2WhatA2sym
ptomA2helpsA2differentiateA2aA2myasthenicA2crisisA2fromA2aA2cholinergicA2crisis?
, AnswerA2Choices
1A2RespiratoryA2failure
2A2BilateralA2ptosis
3A2MuscleA2fasciculations
4A2Diplopia
5A2NormalA2muscleA2stretchA2reflexes
ANS:A23A2-A2Ans--MuscleA2Fasiculations
SignsA2ofA2cholinergicA2overdosageA2includeA2muscleA2fasciculation,A2rhinorrhea,A2lacrim
ation,A2salivation,A2increasedA2bronchialA2secretions,A2nausea,A2orA2diarrhea.A2TheA2pres
enceA2ofA2anyA2ofA2theseA2suggestsA2thatA2theA2patient'sA2weaknessA2mayA2beA2dueA2toA2
cholinergicA2crisis.A2TheA2otherA2signsA2areA2dueA2toA2weaknessA2andA2canA2occurA2inA2eit
herA2condition.
AA254-year-
oldA2manA2presentsA2afterA2havingA2aA2generalizedA2seizure.A2TheA2patientA2isA2HIVA2posi
tive,A2butA2heA2hasA2beenA2unableA2toA2affordA2antiretroviralA2therapyA2sinceA2losingA2hisA2
jobA22A2yearsA2ago.A2OtherA2thanA2cachexia,A2theA2physicalA2examA2isA2unremarkable.A2U
ponA2furtherA2inquiry,A2theA2patientA2alsoA2notesA2thatA2heA2hasA2becomeA2short-
temperedA2andA2hypercritical;A2atA2times,A2heA2seemsA2confused.A2AnA2MRIA2ofA2theA2brai
nA2isA2performed,A2andA2itA2revealsA2severalA2corticalA2ring-enhancingA2lesions.
QuestionA2
WhatA2isA2theA2mostA2likelyA2diagnosis?
AnswerA2Choices
1A2AIDSA2dementiaA2complex
2A2CryptococcalA2meningitis
3A2CytomegalovirusA2encephalitis
4A2ProgressiveA2multifocalA2leukoencephalopathy
5A2ToxoplasmaA2encephalitis
ANS:5A2-A2Ans--ToxoplasmaA2encephalitis
TheA2patient'sA2symptomsA2andA2MRIA2findingsA2areA2mostA2consistentA2withA2theA2diagn
osisA2ofA2toxoplasmaA2encephalitis.A2ToxoplasmosisA2isA2theA2mostA2commonA2cerebralA2
massA2lesionA2amongA2HIV-
positiveA2patients.A2InfectionA2withA2theA2ToxoplasmaA2gondiiA2parasiteA2isA2relativelyA2co
mmonA2andA2usuallyA2asymptomatic.A2ReactivationA2occursA2inA2HIVA2positiveA2patientsA2
dueA2toA2failingA2cellularA2immunity,A2andA2itA2causesA2aA2multifocalA2necrotizingA2enceph
alitis.A2SeizuresA2mayA2beA2theA2initialA2manifestationA2ofA2centralA2nervousA2systemA2(CN
S)A2infection;A2otherA2commonA2clinicalA2manifestationsA2includeA2focalA2neurologicA2defic
its,A2suchA2asA2impairedA2speechA2andA2hemiparesis.A2PersonalityA2change,A2lethargy,A2h
eadache,A2andA2confusionA2areA2alsoA2observed.A2TheA2MRIA2inA2patientsA2withA2toxoplas
maA2encephalitisA2characteristicallyA2revealsA2multiple,A2ring-
enhancingA2lesionsA2withA2surroundingA2edema;A2theseA2lesionsA2usuallyA2occurA2bilatera
llyA2inA2theA2frontalA2andA2parietalA2cortices.
AIDSA2dementiaA2complexA2describesA2aA2constellationA2ofA2cognitiveA2symptomsA2seenA
2amongA2HIVA2positiveA2patients.A2TheA2conditionA2occursA2whenA2HIVA2virusA2disseminat