PHM 350 EXAM 2 QUESTIONS WITH
100% CORRECT ANSWERS LATEST
VERSION 2025/2026.
As a non steroidal anti-inflammatory drug, aspirin:
A. Inhibits the actions of both cyclooxygenase and lipoxygenase
B. Increases phagocytic macrophage migration into tissue at sites of inflammation
C. Is used to treat headache and fever
D. Is used as a prophylactic medication to prevent development of arthritis
E. None of the above. - ANS C. Is used to treat headache and fever
As a non steroidal anti-inflammatory drug, aspirin:
A. Increases the activity and effects of cyclooxygenase but not of lipoxygenase
B. Decreases phagocytic macrophage migration into tissue at sites of inflammation
C. Is used to treat headache and fever because it does not cause irritation of the gastro-
intestinal tract
D. Is used to prevent osteoporosis
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,E. A and C, above. - ANS B. Decreases phagocytic macrophage migration into tissue at sites of
inflammation
Glucocorticoids such as predisnone (DELTASONE):
A. Induce hyperglycemia
B. Are useful to treat Type II diabetes
C. Are used to treat conditions characterized by chronic inflammation
D. Treat Type I diabetes because these drugs induce release insulin from the pancreas
E. A and C, above. - ANS E. A and C, above.
Which of the following statements about anti-inflammatory drugs is correct?
A. One of the more frequent adverse side effects of indomethacin (INDOCIN) is metaboliC
acidosis
B. One of the more frequent adverse side effects of aspirin is bone marrow suppression
C. One of the more frequent adverse side effects of prednisone (DELTASONE) is
development of osteoporosis
D. One of the more frequent adverse side effects of low dose aspirin is suppression of blood
clotting processes
E. A and C, above. - ANS C. One of the more frequent adverse side effects of prednisone
(DELTASONE) is
development of osteoporosis
Which of the following drugs causes hepatotoxicity in overdose?
A. Celecoxib (CELEBREX)
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,B. Prednisone (DELTASONE)
C. Acetaminophen (TYLENOL)
D. Ibuprofen (MOTRIN)
E. A and C, above. - ANS C. Acetaminophen (TYLENOL)
The advantage of using celecoxib (CELEBREX) for treatment of arthritis pain (compared to use of
aspirin) is that:
A. Celecoxib produces gastrointestinal irritation at a lower incidence than aspirin does
B. Celecoxib is a lipoxygenase inhibitor and aspirin is not
C. Celecoxib inhibits COX-2 but not COX-1 but aspirin only inhibits COX-1
D. Celecoxib increases blood flow to the inflamed joints
E. A and C, above. - ANS A. Celecoxib produces gastrointestinal irritation at a lower incidence
than aspirin does
Indomethacin (INDOCIN) is used to treat:
A. Gout
B. Infertility
C. Rheumatoid arthritis
D. Congestive heart failure
E. A and C. - ANS E. A and C.
Acetaminophen (TYLENOL):
A. Like aspirin is a useful anti-pyretic drug because it inhibits central cyclooxygenases
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, B. Blocks pain pathways in the central nervous system
C. Is a weak antiinflammatory drug because it is bound/inhibited by peroxide compounds
formed at sites of inflammation
D. Alters cellular respiration and upsets blood acid-base balance
E. A and C, above. - ANS E. A and C, above.
COX inhibitors:
A. Interfere with neuronal opiate receptor pain pathways
B. Are anti-inflammatory drugs because they reduce leukotriene production
C. Cause altered metabolism of carbohydrate, fat, and protein
D. Reduce pain sensitivity at sites throughout the body (not just at sites of inflammation)
E. None of the above. - ANS E. None of the above.
A drug which has anti-inflammatory effects because it increases lipocortin in so called
"inflammatory cells":
A. Prednisone (DELTASONE)
B. Montelukast (SINGULAIR)
C. Aspirin
D. Zileuton (ZYFLO)
E. A and C above. - ANS A. Prednisone (DELTASONE)
Dexamethasone (MAXIDEX) is used to treat:
A. Headache
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
100% CORRECT ANSWERS LATEST
VERSION 2025/2026.
As a non steroidal anti-inflammatory drug, aspirin:
A. Inhibits the actions of both cyclooxygenase and lipoxygenase
B. Increases phagocytic macrophage migration into tissue at sites of inflammation
C. Is used to treat headache and fever
D. Is used as a prophylactic medication to prevent development of arthritis
E. None of the above. - ANS C. Is used to treat headache and fever
As a non steroidal anti-inflammatory drug, aspirin:
A. Increases the activity and effects of cyclooxygenase but not of lipoxygenase
B. Decreases phagocytic macrophage migration into tissue at sites of inflammation
C. Is used to treat headache and fever because it does not cause irritation of the gastro-
intestinal tract
D. Is used to prevent osteoporosis
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,E. A and C, above. - ANS B. Decreases phagocytic macrophage migration into tissue at sites of
inflammation
Glucocorticoids such as predisnone (DELTASONE):
A. Induce hyperglycemia
B. Are useful to treat Type II diabetes
C. Are used to treat conditions characterized by chronic inflammation
D. Treat Type I diabetes because these drugs induce release insulin from the pancreas
E. A and C, above. - ANS E. A and C, above.
Which of the following statements about anti-inflammatory drugs is correct?
A. One of the more frequent adverse side effects of indomethacin (INDOCIN) is metaboliC
acidosis
B. One of the more frequent adverse side effects of aspirin is bone marrow suppression
C. One of the more frequent adverse side effects of prednisone (DELTASONE) is
development of osteoporosis
D. One of the more frequent adverse side effects of low dose aspirin is suppression of blood
clotting processes
E. A and C, above. - ANS C. One of the more frequent adverse side effects of prednisone
(DELTASONE) is
development of osteoporosis
Which of the following drugs causes hepatotoxicity in overdose?
A. Celecoxib (CELEBREX)
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,B. Prednisone (DELTASONE)
C. Acetaminophen (TYLENOL)
D. Ibuprofen (MOTRIN)
E. A and C, above. - ANS C. Acetaminophen (TYLENOL)
The advantage of using celecoxib (CELEBREX) for treatment of arthritis pain (compared to use of
aspirin) is that:
A. Celecoxib produces gastrointestinal irritation at a lower incidence than aspirin does
B. Celecoxib is a lipoxygenase inhibitor and aspirin is not
C. Celecoxib inhibits COX-2 but not COX-1 but aspirin only inhibits COX-1
D. Celecoxib increases blood flow to the inflamed joints
E. A and C, above. - ANS A. Celecoxib produces gastrointestinal irritation at a lower incidence
than aspirin does
Indomethacin (INDOCIN) is used to treat:
A. Gout
B. Infertility
C. Rheumatoid arthritis
D. Congestive heart failure
E. A and C. - ANS E. A and C.
Acetaminophen (TYLENOL):
A. Like aspirin is a useful anti-pyretic drug because it inhibits central cyclooxygenases
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, B. Blocks pain pathways in the central nervous system
C. Is a weak antiinflammatory drug because it is bound/inhibited by peroxide compounds
formed at sites of inflammation
D. Alters cellular respiration and upsets blood acid-base balance
E. A and C, above. - ANS E. A and C, above.
COX inhibitors:
A. Interfere with neuronal opiate receptor pain pathways
B. Are anti-inflammatory drugs because they reduce leukotriene production
C. Cause altered metabolism of carbohydrate, fat, and protein
D. Reduce pain sensitivity at sites throughout the body (not just at sites of inflammation)
E. None of the above. - ANS E. None of the above.
A drug which has anti-inflammatory effects because it increases lipocortin in so called
"inflammatory cells":
A. Prednisone (DELTASONE)
B. Montelukast (SINGULAIR)
C. Aspirin
D. Zileuton (ZYFLO)
E. A and C above. - ANS A. Prednisone (DELTASONE)
Dexamethasone (MAXIDEX) is used to treat:
A. Headache
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
