PHM 350 MSU EXAM 1 QUESTIONS
WITH 100% CORRECT ANSWERS
LATEST VERSION 2025/2026.
IN the figures below which has the greater potency?
Drug A
B
C
D - ANS Drug B
Which is used to orthostatic hypotension?
A. isoprotenerenol (ISUPREL)
B.Midodrine (AMANTINE)
C. brimonidine (ALPHAGAN)
D. Albuterol (VENTOILIN)
E. A & C - ANS B. MIDODRINE
Which has the largest therapeutic window?
A: Drug A
B
C
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,D - ANS Drug D
Isoproterenol (ISUPREL) will decrease blood pressure by:
A: activation of alpha adreoreceptors on blood vessels of the skin and mesentery
B. activation of beta2 adrenoreceptors on the blood vessels of skeletal m
C: blockage of alpha 1 adrenoreceptors on blood vessels of the skin and mesentery
D: Blockage of beta2 adrenoreceptors on the blood vessels of skeletal m
E: none of these - ANS B. activation of beta2 adrenoreceptors on the blood vessels of skeletal
m
Drug A has t1/2 value whihc is half the t1/2 value of Drug B. IN comparing the use of these
drugs, it is likely that Drug A:
A: is more likely than drug B to produce adverse side efects
B: will be given more frequently than drug B
C: will be given less frequently than Drug B
D: A & B
E. none of the above - ANS B: will be given more frequently than drug B
in the figure below, which statement best fits what you see?
A: fo the response being measures, Drugs A & B are equally potent
B: Drug A is les potent than Drug B
C: Drugs A&B both agonists at te receptor mediating the response being measured
D: If drugs A & B both induce this effect by activating same type of receptor, A have greater
affinity
E: A&C - ANS E: A&C
Bethanechol (URECHOLINE)
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, A: is choline ester that is also a cholinomimetic
B: has a high affinity for nicotinic cholinergic receptors
C: high affinity for muscuarinic cholinergic receptors
D: is useful therapeutically bc it is substrate for cholinesterases
E: A&C - ANS E: A&C
Liver enzyme, Z, metabolizes drug A. if drug A is administered repeatedly, then the amount of Z
in the liver increased. Consequently.
A: the half ife of drug A wil be increased
B: the hallife of drug B also metabolizes by Z will not be affected
C: half life of all drugs metab by Z will be decreased
D: the rate of metaboism of Drug A will not change
E: A &C - ANS C: half life of all drugs metab by Z will be decreased
therapeutic threshold concentration of a drug
A: is affected by ability fo body to eliminate the drug
B: the minimu plamsa concentration of the drug which is required to induce the desired
therapeutic response
C: depends on the rate of absorption of the drug
D: determines the pharmacological and clinical efficacies of the drug
E: A&C - ANS B: the minimu plamsa concentration of the drug which is required to induce the
desired therapeutic response
Edrophonium (TENSILON) preferred over others differentially diagnose myasthenia gravis from
other muscle weakness conditions bc:
A: its a Nm nicotinic receptor agonist
B: its a Nm nicotinic receptor antagonist
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
WITH 100% CORRECT ANSWERS
LATEST VERSION 2025/2026.
IN the figures below which has the greater potency?
Drug A
B
C
D - ANS Drug B
Which is used to orthostatic hypotension?
A. isoprotenerenol (ISUPREL)
B.Midodrine (AMANTINE)
C. brimonidine (ALPHAGAN)
D. Albuterol (VENTOILIN)
E. A & C - ANS B. MIDODRINE
Which has the largest therapeutic window?
A: Drug A
B
C
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,D - ANS Drug D
Isoproterenol (ISUPREL) will decrease blood pressure by:
A: activation of alpha adreoreceptors on blood vessels of the skin and mesentery
B. activation of beta2 adrenoreceptors on the blood vessels of skeletal m
C: blockage of alpha 1 adrenoreceptors on blood vessels of the skin and mesentery
D: Blockage of beta2 adrenoreceptors on the blood vessels of skeletal m
E: none of these - ANS B. activation of beta2 adrenoreceptors on the blood vessels of skeletal
m
Drug A has t1/2 value whihc is half the t1/2 value of Drug B. IN comparing the use of these
drugs, it is likely that Drug A:
A: is more likely than drug B to produce adverse side efects
B: will be given more frequently than drug B
C: will be given less frequently than Drug B
D: A & B
E. none of the above - ANS B: will be given more frequently than drug B
in the figure below, which statement best fits what you see?
A: fo the response being measures, Drugs A & B are equally potent
B: Drug A is les potent than Drug B
C: Drugs A&B both agonists at te receptor mediating the response being measured
D: If drugs A & B both induce this effect by activating same type of receptor, A have greater
affinity
E: A&C - ANS E: A&C
Bethanechol (URECHOLINE)
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, A: is choline ester that is also a cholinomimetic
B: has a high affinity for nicotinic cholinergic receptors
C: high affinity for muscuarinic cholinergic receptors
D: is useful therapeutically bc it is substrate for cholinesterases
E: A&C - ANS E: A&C
Liver enzyme, Z, metabolizes drug A. if drug A is administered repeatedly, then the amount of Z
in the liver increased. Consequently.
A: the half ife of drug A wil be increased
B: the hallife of drug B also metabolizes by Z will not be affected
C: half life of all drugs metab by Z will be decreased
D: the rate of metaboism of Drug A will not change
E: A &C - ANS C: half life of all drugs metab by Z will be decreased
therapeutic threshold concentration of a drug
A: is affected by ability fo body to eliminate the drug
B: the minimu plamsa concentration of the drug which is required to induce the desired
therapeutic response
C: depends on the rate of absorption of the drug
D: determines the pharmacological and clinical efficacies of the drug
E: A&C - ANS B: the minimu plamsa concentration of the drug which is required to induce the
desired therapeutic response
Edrophonium (TENSILON) preferred over others differentially diagnose myasthenia gravis from
other muscle weakness conditions bc:
A: its a Nm nicotinic receptor agonist
B: its a Nm nicotinic receptor antagonist
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
