Test bank for Clinical Chemistry: Principles,
Techniques, and Correlations with Navigate
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1. Extreme copper deficiency is seen in what fatal condition?
a. Menkes disease
b. Klinefelter's syndrome
c. Meese disease
d. Kayser-Fleischer rings - answers a. Menkes disease
2. Suppose the controller on a GFAAS is defective and the furnace is running cold.
What effect will this likely have on the number of photons absorbed in
the measurements?
a. It will decrease the number of photons absorbed
b. It will increase the number of photons absorbed
c. It will have little effect
d. It is not a relevant question because AAS relies
on emission of light from electronically excited atoms - answers a. It will decrease the
number of photons absorbed
3. Why would a clinical chemist develop an arsenic method that combines liquid
chromatography with ICP-MS?
a. To separate and quantitate several different arsenic-containing species in the same
sample
b. To eliminate interference by sodium from the
analysis
c. To shorten the run time of the measurement
d. To lower the coefficient of variation for total
arsenic measurements - answers a. To separate and quantitate several different
arsenic-containing species in the same sample
4. Select the answer that designates three techniques widely used for elemental
analysis, identified according to the initials for the techniques.
a. AAS, ICP-MS, AES
b. NMR, ICP-MS, AES
c. GC-MS, ICP-MS, AES
d. HPLC-ICP-MS, AAS, FTIR - answers a. AAS, ICP-MS, AES
5. One of the calcium isotopes (40Ca) has an atomic weight of 40. At what positions in a
mass spec- trum would singly and doubly charged ions of this isotope of calcium
appear? Assume that singly charged Ca is listed first.
a. 40 and 20
,b. 40 and 60
c. 40 and 80
d. 40 and 40 - answers a. 40 and 20
6. What primary purposes does the torch serve in ICP-MS?
a. Vaporization, atomization, and ionization
b. Vaporization, atomization, and electronic
excitation
c. Nebulization, atomization, and photon
absorption
d. Droplet transport, vaporization, and ion
detection - answers a. Vaporization, atomization, and ionization
7. Manganese toxicity resembles the following disease:
a. Parkinson's disease
b. Wilson's disease
c. Alzheimer's disease
d. Menkes disease - answers a. Parkinson's disease
8. Iron is physiologically active only in the ferrous form in
a. Hemoglobin
b. Cytochromes
c. Ferritin
d. Transferrin - answers a. Hemoglobin
9. A metal ion required for optimal enzyme activity is best termed a(an)
a. Cofactor
b. Accelerator
c. Coenzyme
d. Catalyst - answers a. Cofactor
10. Which trace metal is contained in glucose tolerance factor?
a. Chromium
b. Copper
c. Selenium
d. Zinc - answers a. Chromium
11. What metal may be used as a treatment for Wilson's disease?
a. Zinc
b. Copper
c. Molybdenum
d. Fluorine - answers a. Zinc
12. The metal ion essential for the activity of xanthine oxidase and xanthine
dehydrogenase is
a. Molybdenum
, b. Iron
c. Zinc
d. Manganese - answers a. Molybdenum
One nanogram - answers is equivalent to 10-9 grams.
0.5N NaOH required to make 100 mL of 0.2N NaOH - answers 40 milliliters.
Concentration of uric acid in patient's sample - answers 200 grams per deciliter.
Millimoles of NaCl in 300 mL of a 4M solution - answers 1200 millimoles.
10 mg/dL of calcium reported in mmol/L - answers 2.5 mmol/L.
Concentrated sulfuric acid needed for 400 mL of a 2N solution - answers 32.7 milliliters.
Grams of hydrated MgSO4 · 5 H2O for a 10% solution - answers 17.6 grams per
deciliter.
Molarity (M) of a 4% solution of sodium hydroxide (NaOH) - answers Calculated based
on the molecular weight.
0.1M - answers A molarity concentration representing 0.1 moles of solute per liter of
solution.
0.25M - answers A molarity concentration representing 0.25 moles of solute per liter of
solution.
1.0M - answers A molarity concentration representing 1.0 moles of solute per liter of
solution.
2.5M - answers A molarity concentration representing 2.5 moles of solute per liter of
solution.
3 mg/dL - answers Equivalent to 0.03 grams per liter.
Normality of a solution - answers The measure of concentration equivalent to the
number of equivalents of solute per liter of solution.
4.5 grams of BaCl2 in 400 mL - answers Results in a normality of 0.11.
Optimal conditions for specimen transport - answers Specimen transported to lab
immediately, permitted to clot, serum separated and tested as soon as possible.
Fastest turnaround times for blood gas analysis - answers Whole blood specimens
provide the fastest turnaround times.
Techniques, and Correlations with Navigate
Advantage Access | 2025 version | All
chapters | PASS Guaranteed|
1. Extreme copper deficiency is seen in what fatal condition?
a. Menkes disease
b. Klinefelter's syndrome
c. Meese disease
d. Kayser-Fleischer rings - answers a. Menkes disease
2. Suppose the controller on a GFAAS is defective and the furnace is running cold.
What effect will this likely have on the number of photons absorbed in
the measurements?
a. It will decrease the number of photons absorbed
b. It will increase the number of photons absorbed
c. It will have little effect
d. It is not a relevant question because AAS relies
on emission of light from electronically excited atoms - answers a. It will decrease the
number of photons absorbed
3. Why would a clinical chemist develop an arsenic method that combines liquid
chromatography with ICP-MS?
a. To separate and quantitate several different arsenic-containing species in the same
sample
b. To eliminate interference by sodium from the
analysis
c. To shorten the run time of the measurement
d. To lower the coefficient of variation for total
arsenic measurements - answers a. To separate and quantitate several different
arsenic-containing species in the same sample
4. Select the answer that designates three techniques widely used for elemental
analysis, identified according to the initials for the techniques.
a. AAS, ICP-MS, AES
b. NMR, ICP-MS, AES
c. GC-MS, ICP-MS, AES
d. HPLC-ICP-MS, AAS, FTIR - answers a. AAS, ICP-MS, AES
5. One of the calcium isotopes (40Ca) has an atomic weight of 40. At what positions in a
mass spec- trum would singly and doubly charged ions of this isotope of calcium
appear? Assume that singly charged Ca is listed first.
a. 40 and 20
,b. 40 and 60
c. 40 and 80
d. 40 and 40 - answers a. 40 and 20
6. What primary purposes does the torch serve in ICP-MS?
a. Vaporization, atomization, and ionization
b. Vaporization, atomization, and electronic
excitation
c. Nebulization, atomization, and photon
absorption
d. Droplet transport, vaporization, and ion
detection - answers a. Vaporization, atomization, and ionization
7. Manganese toxicity resembles the following disease:
a. Parkinson's disease
b. Wilson's disease
c. Alzheimer's disease
d. Menkes disease - answers a. Parkinson's disease
8. Iron is physiologically active only in the ferrous form in
a. Hemoglobin
b. Cytochromes
c. Ferritin
d. Transferrin - answers a. Hemoglobin
9. A metal ion required for optimal enzyme activity is best termed a(an)
a. Cofactor
b. Accelerator
c. Coenzyme
d. Catalyst - answers a. Cofactor
10. Which trace metal is contained in glucose tolerance factor?
a. Chromium
b. Copper
c. Selenium
d. Zinc - answers a. Chromium
11. What metal may be used as a treatment for Wilson's disease?
a. Zinc
b. Copper
c. Molybdenum
d. Fluorine - answers a. Zinc
12. The metal ion essential for the activity of xanthine oxidase and xanthine
dehydrogenase is
a. Molybdenum
, b. Iron
c. Zinc
d. Manganese - answers a. Molybdenum
One nanogram - answers is equivalent to 10-9 grams.
0.5N NaOH required to make 100 mL of 0.2N NaOH - answers 40 milliliters.
Concentration of uric acid in patient's sample - answers 200 grams per deciliter.
Millimoles of NaCl in 300 mL of a 4M solution - answers 1200 millimoles.
10 mg/dL of calcium reported in mmol/L - answers 2.5 mmol/L.
Concentrated sulfuric acid needed for 400 mL of a 2N solution - answers 32.7 milliliters.
Grams of hydrated MgSO4 · 5 H2O for a 10% solution - answers 17.6 grams per
deciliter.
Molarity (M) of a 4% solution of sodium hydroxide (NaOH) - answers Calculated based
on the molecular weight.
0.1M - answers A molarity concentration representing 0.1 moles of solute per liter of
solution.
0.25M - answers A molarity concentration representing 0.25 moles of solute per liter of
solution.
1.0M - answers A molarity concentration representing 1.0 moles of solute per liter of
solution.
2.5M - answers A molarity concentration representing 2.5 moles of solute per liter of
solution.
3 mg/dL - answers Equivalent to 0.03 grams per liter.
Normality of a solution - answers The measure of concentration equivalent to the
number of equivalents of solute per liter of solution.
4.5 grams of BaCl2 in 400 mL - answers Results in a normality of 0.11.
Optimal conditions for specimen transport - answers Specimen transported to lab
immediately, permitted to clot, serum separated and tested as soon as possible.
Fastest turnaround times for blood gas analysis - answers Whole blood specimens
provide the fastest turnaround times.
