Women’s Health Nurse Practitioner (WHNP)
Certification Exam 100 Questions And
Correct Answers (Verified Answers) Plus
Rationales 2025/2026 Q&A | Instant
Download Pdf
1. Which hormone is primarily responsible for the LH surge
preceding ovulation?
A. Progesterone
B. Estradiol
C. Inhibin
D. FSH
Estradiol peaks mid-cycle and triggers the LH surge that induces
ovulation.
2. The most common cause of secondary amenorrhea in
reproductive-age women is:
A. Hyperprolactinemia
B. Thyroid disease
C. Premature ovarian insufficiency
D. Pregnancy
Pregnancy is always the first diagnosis to rule out in secondary
amenorrhea.
3. A 24-year-old presents with dysuria, sterile pyuria, and
mucopurulent cervical discharge. Most likely cause?
,A. Candida
B. Trichomonas
C. Chlamydia trachomatis
D. BV
Chlamydia can produce dysuria and sterile pyuria with minimal
findings.
4. Which contraceptive method is contraindicated in a woman with
migraine with aura?
A. Copper IUD
B. Combined oral contraceptives
C. LNG-IUD
D. Barrier methods
Estrogen increases risk of stroke in migraine with aura.
5. A Pap smear shows ASC-US. HPV test is positive. Appropriate
next step?
A. Repeat Pap in 3 years
B. Colposcopy
C. HPV vaccine
D. Treat for CIN
ASC-US + HPV+ requires colposcopy.
6. First-line treatment for uncomplicated cystitis in nonpregnant
women?
A. Ciprofloxacin
B. Nitrofurantoin
C. Amoxicillin
, D. Metronidazole
Nitrofurantoin is recommended unless contraindicated.
7. Most common site for endometriosis implantation:
A. Rectum
B. Cervix
C. Ovaries
D. Bladder
Ovaries are the most frequent site of lesions.
8. A 48-year-old has irregular menses, hot flashes, and night
sweats. FSH is elevated. Diagnosis?
A. Hypothyroidism
B. Hyperprolactinemia
C. PCOS
D. Perimenopause
High FSH and vasomotor symptoms indicate the menopausal
transition.
9. Which STI causes a painless genital ulcer?
A. HSV
B. Syphilis
C. Chancroid
D. LGV
A syphilis chancre is firm, round, painless.
10. Contraindication to hormonal IUD placement:
Certification Exam 100 Questions And
Correct Answers (Verified Answers) Plus
Rationales 2025/2026 Q&A | Instant
Download Pdf
1. Which hormone is primarily responsible for the LH surge
preceding ovulation?
A. Progesterone
B. Estradiol
C. Inhibin
D. FSH
Estradiol peaks mid-cycle and triggers the LH surge that induces
ovulation.
2. The most common cause of secondary amenorrhea in
reproductive-age women is:
A. Hyperprolactinemia
B. Thyroid disease
C. Premature ovarian insufficiency
D. Pregnancy
Pregnancy is always the first diagnosis to rule out in secondary
amenorrhea.
3. A 24-year-old presents with dysuria, sterile pyuria, and
mucopurulent cervical discharge. Most likely cause?
,A. Candida
B. Trichomonas
C. Chlamydia trachomatis
D. BV
Chlamydia can produce dysuria and sterile pyuria with minimal
findings.
4. Which contraceptive method is contraindicated in a woman with
migraine with aura?
A. Copper IUD
B. Combined oral contraceptives
C. LNG-IUD
D. Barrier methods
Estrogen increases risk of stroke in migraine with aura.
5. A Pap smear shows ASC-US. HPV test is positive. Appropriate
next step?
A. Repeat Pap in 3 years
B. Colposcopy
C. HPV vaccine
D. Treat for CIN
ASC-US + HPV+ requires colposcopy.
6. First-line treatment for uncomplicated cystitis in nonpregnant
women?
A. Ciprofloxacin
B. Nitrofurantoin
C. Amoxicillin
, D. Metronidazole
Nitrofurantoin is recommended unless contraindicated.
7. Most common site for endometriosis implantation:
A. Rectum
B. Cervix
C. Ovaries
D. Bladder
Ovaries are the most frequent site of lesions.
8. A 48-year-old has irregular menses, hot flashes, and night
sweats. FSH is elevated. Diagnosis?
A. Hypothyroidism
B. Hyperprolactinemia
C. PCOS
D. Perimenopause
High FSH and vasomotor symptoms indicate the menopausal
transition.
9. Which STI causes a painless genital ulcer?
A. HSV
B. Syphilis
C. Chancroid
D. LGV
A syphilis chancre is firm, round, painless.
10. Contraindication to hormonal IUD placement:
