how is inflammation beneficial? - answer-it clears waste products and gives room for tissue
repair
what would happen if there was a total lack of inflammation? - answer-wounds would never heal
what is the definition of inflammation? - answer-complex reaction to injurious agents such as
microbes and damaged, usually necrotic, cells that consists off vascular responses, migration
and activation of leukocytes, and systemic reactions
what is the most important feature of inflammation? - answer-vascular response--> extracellular
accumulation of fluid and blood leukocytes
what is the purpose of inflammation? - answer-mainly protective but also harmful (like chronic
inflammatory diseases)
what are the main components of inflammation? - answer-vascular events
cellular events
into what designations is inflammation divided? - answer-acute inflammation
chronic inflammation
what are the mediators of both acute and chronic inflammation? - answer-mainly chemical
factors
what does increased vascular permeability in inflammation cause? - answer-extravasation of the
fluids --> edema
,what is the most cardinal feature of acute inflammation? - answer-edema
what is the timeframe of acute inflammation? - answer-<=24h
what cells are associated with acute inflammation? - answer-neutrophils (generally)
what is the cell response of most bacterial infections within 24h? - answer-neutrophils
what is the cell response of whooping cough and viral infections in 24h? - answer-lymphocytes
what is the timeframe of chronic inflammation? - answer-> 24h
what cells are associated with chronic inflammation? - answer-lymphocytes
plasma cells
monocytes
what is the infiltrate associated with chronic inflammation? - answer-lymphomononuclear
infiltrate
when do secondary granules develop in hematopoiesis? - answer-myelocytic stage
who described the 4 original cardinal signs of inflammation? - answer-Celsus
what are the cardinal signs of inflammation? - answer-1. rubor
2. tumor
3. calor
4. dolor
, 5. functio laesa
what did Sir Thomas Lewis discover about inflammation? - answer-the triple response
(histamine mediate the vascular changes of inflammation
what causes rubor? - answer-increased arterial bloodflow and caliber
what is the word for new growth, colloquially known as tumor? - answer-neoplasm
what causes calor? - answer-warmth of arterial blood
what does alteration in vascular caliber in acute inflammation cause? - answer-increase in
bloodflow
what are the components of acute inflammation? - answer-alterations in vascular caliber results
in an increase in blood flow
structural changes in the microvasculature
emigration of the leukocytes
what is pus? - answer-purulent inflammatory exudate
what is pus made of? - answer-rich in leukocytes (neutrophils live or dead), cellular debris,
microbes
what is edema? - answer-excess of fluid in the interstitial or serous cavities
what is the cause of exudate? - answer-always inflammation
what is the cause of transudate? - answer-inflammation and various other causes