COURSE 2025/2026 | QUESTION BANK | VERIFIED
QUESTIONS AND ANSWERS GRADED A+ | IMMUNE
SYSTEM STRUCTURE & FUNCTION STUDY GUIDE |
GUARANTEED SUCCESS
T-cell receptor δ-chain gene - CORRECT ANSWER -positioned in the T-cell
receptor α-chain locus between Vα and Jα gene segments
CD3 complex - CORRECT ANSWER -made up of γ, δ and ε components
T-cell receptor β-chain gene - CORRECT ANSWER -located on chromosome
7
CD4 - CORRECT ANSWER -four extracellular domains
T-cell receptor γ-chain gene - CORRECT ANSWER -counterpart to the T-cell
receptor α-chain gene
During T-cell receptor _____-gene rearrangement, two D segments may be used
in the final rearranged gene sequence, thereby increasing overall variability of
this chain. - CORRECT ANSWER -δ
The degradation of pathogen proteins into smaller fragments called peptides is a
process commonly referred to as - CORRECT ANSWER -antigen processing
All of the following are primarily associated with CD4 T-cell function except -
CORRECT ANSWER -kill virus-infected cells
, The primary reason for transplant rejections is due to differences in _____
between donor and recipient. - CORRECT ANSWER -MHC molecules
When describing the various components of the vesicular system, which of the
following is not included? - CORRECT ANSWER -nucleus
Which of the following is not a characteristic of immunoproteasomes? -
CORRECT ANSWER -They produce a higher proportion of peptides
containing acidic amino acids at the carboxy terminus compared with
constitutive proteasomes.
T cells recognize antigen when the antigen - CORRECT ANSWER -forms a
complex with membrane-bound MHC molecules on another host-derived cell
T-cell receptors structurally resemble - CORRECT ANSWER -a single Fab of
immunoglobulins
If viewing the three-dimensional structure of a T-cell receptor from the side,
with the T-cell membrane at the bottom and the receptor pointing upwards,
which of the following is inconsistent with experimental data? - CORRECT
ANSWER -The portion that makes physical contact with the ligand comprises
Vβ and Cβ, the domains farthest from the T-cell membrane.
Unlike B cells, T cells do not engage in any of the following processes except -
CORRECT ANSWER -somatic recombination
When comparing the T-cell receptor α-chain locus with the immunoglobulin
heavy-chain locus, all of the following are correct except - CORRECT
ANSWER -the T-cell receptor α-chain locus contains more C regions
Unlike the C regions of immunoglobulin heavy-chain loci, the C regions of the
T-cell receptor β-chain loci - CORRECT ANSWER -are functionally similar