RN Medical Surgical Neurosensory
and Immune System Prep Test 2026
Test Bank with Real Exam Questions
and 100% Correct Answers Graded A+
1. A patient presents with sudden unilateral facial droop and inability to
close the eye. What is the most likely diagnosis?
A. Stroke
B. Bell’s Palsy
C. Myasthenia Gravis
D. Trigeminal Neuralgia
Answer: B – Bell’s Palsy
Rationale: Acute onset of unilateral facial weakness, inability to close the
eye, and drooping mouth are characteristic of Bell’s Palsy, usually
idiopathic or viral-related.
2. Which cranial nerve is involved in hearing loss and vertigo?
A. CN V
B. CN VII
C. CN VIII
D. CN IX
Answer: C – CN VIII
Rationale: Vestibulocochlear nerve (CN VIII) transmits auditory
,information and maintains balance; lesions cause hearing loss, tinnitus,
and vertigo.
3. A patient with MS reports diplopia and fatigue. Which intervention is
priority?
A. Schedule MRI
B. Administer corticosteroids
C. Provide energy conservation education
D. Encourage high-protein diet
Answer: C – Energy conservation
Rationale: Fatigue is the most common symptom in MS. Education on
energy conservation improves quality of life; other interventions depend
on acute exacerbations.
4. Which laboratory test is most indicative of HIV infection?
A. CBC
B. ELISA
C. Liver function tests
D. Serum protein electrophoresis
Answer: B – ELISA
Rationale: ELISA detects HIV antibodies and is the initial screening test;
positive results require confirmatory Western blot or PCR.
5. A patient is receiving IVIG therapy for autoimmune disease. What is
the primary nursing consideration?
,A. Monitor for hyperkalemia
B. Assess for anaphylaxis
C. Limit fluids to prevent overload
D. Encourage high-calcium diet
Answer: B – Assess for anaphylaxis
Rationale: IVIG can trigger allergic reactions, including anaphylaxis;
monitor closely during infusion.
6. A patient with Guillain-Barre Syndrome exhibits ascending
weakness. What is the priority?
A. Initiate physical therapy
B. Monitor respiratory function
C. Start corticosteroids
D. Assess bowel habits
Answer: B – Monitor respiratory function
Rationale: Ascending paralysis can involve respiratory muscles; early
detection of respiratory compromise is critical.
7. Which vaccine is recommended for immunocompromised adults?
A. Live attenuated influenza
B. MMR
C. Inactivated influenza
D. Varicella
Answer: C – Inactivated influenza
Rationale: Live vaccines are contraindicated in immunocompromised
adults; inactivated vaccines are safe.
, 8. A patient has lupus and presents with joint pain and rash. Which lab
is most specific for lupus?
A. ANA
B. Anti-dsDNA
C. ESR
D. CRP
Answer: B – Anti-dsDNA
Rationale: ANA is sensitive but not specific; Anti-dsDNA antibodies are
highly specific for systemic lupus erythematosus (SLE).
9. A patient with myasthenia gravis develops ptosis and difficulty
swallowing. Which medication should be held?
A. Pyridostigmine
B. Aminoglycosides
C. Prednisone
D. IVIG
Answer: B – Aminoglycosides
Rationale: Aminoglycosides can worsen neuromuscular transmission and
exacerbate myasthenic crisis.
10. A patient presents with a stiff neck, fever, and photophobia. What is
the priority nursing action?
A. Administer antibiotics immediately
B. Perform lumbar puncture
and Immune System Prep Test 2026
Test Bank with Real Exam Questions
and 100% Correct Answers Graded A+
1. A patient presents with sudden unilateral facial droop and inability to
close the eye. What is the most likely diagnosis?
A. Stroke
B. Bell’s Palsy
C. Myasthenia Gravis
D. Trigeminal Neuralgia
Answer: B – Bell’s Palsy
Rationale: Acute onset of unilateral facial weakness, inability to close the
eye, and drooping mouth are characteristic of Bell’s Palsy, usually
idiopathic or viral-related.
2. Which cranial nerve is involved in hearing loss and vertigo?
A. CN V
B. CN VII
C. CN VIII
D. CN IX
Answer: C – CN VIII
Rationale: Vestibulocochlear nerve (CN VIII) transmits auditory
,information and maintains balance; lesions cause hearing loss, tinnitus,
and vertigo.
3. A patient with MS reports diplopia and fatigue. Which intervention is
priority?
A. Schedule MRI
B. Administer corticosteroids
C. Provide energy conservation education
D. Encourage high-protein diet
Answer: C – Energy conservation
Rationale: Fatigue is the most common symptom in MS. Education on
energy conservation improves quality of life; other interventions depend
on acute exacerbations.
4. Which laboratory test is most indicative of HIV infection?
A. CBC
B. ELISA
C. Liver function tests
D. Serum protein electrophoresis
Answer: B – ELISA
Rationale: ELISA detects HIV antibodies and is the initial screening test;
positive results require confirmatory Western blot or PCR.
5. A patient is receiving IVIG therapy for autoimmune disease. What is
the primary nursing consideration?
,A. Monitor for hyperkalemia
B. Assess for anaphylaxis
C. Limit fluids to prevent overload
D. Encourage high-calcium diet
Answer: B – Assess for anaphylaxis
Rationale: IVIG can trigger allergic reactions, including anaphylaxis;
monitor closely during infusion.
6. A patient with Guillain-Barre Syndrome exhibits ascending
weakness. What is the priority?
A. Initiate physical therapy
B. Monitor respiratory function
C. Start corticosteroids
D. Assess bowel habits
Answer: B – Monitor respiratory function
Rationale: Ascending paralysis can involve respiratory muscles; early
detection of respiratory compromise is critical.
7. Which vaccine is recommended for immunocompromised adults?
A. Live attenuated influenza
B. MMR
C. Inactivated influenza
D. Varicella
Answer: C – Inactivated influenza
Rationale: Live vaccines are contraindicated in immunocompromised
adults; inactivated vaccines are safe.
, 8. A patient has lupus and presents with joint pain and rash. Which lab
is most specific for lupus?
A. ANA
B. Anti-dsDNA
C. ESR
D. CRP
Answer: B – Anti-dsDNA
Rationale: ANA is sensitive but not specific; Anti-dsDNA antibodies are
highly specific for systemic lupus erythematosus (SLE).
9. A patient with myasthenia gravis develops ptosis and difficulty
swallowing. Which medication should be held?
A. Pyridostigmine
B. Aminoglycosides
C. Prednisone
D. IVIG
Answer: B – Aminoglycosides
Rationale: Aminoglycosides can worsen neuromuscular transmission and
exacerbate myasthenic crisis.
10. A patient presents with a stiff neck, fever, and photophobia. What is
the priority nursing action?
A. Administer antibiotics immediately
B. Perform lumbar puncture
