MCB2050 Post MT Exam Questions With Complete Solutions

MCB2050 Post MT Exam Questions With Complete
Solutions

___________ refers to the minimum distance that can separate
two pts while still maintaining the ability to distinguish them as
separate points Correct Answers Resolution

A membrane protein en route from the ER to the Golgi would
require which of the following signals in order to be recruited
into a COP II vesicle? Correct Answers ER exit signal

Act like a sieve which allows for the passive diffusion of small
molecules thru the NPC while excluding others Correct Answers
FG nucleoporins

consist mostly of highly curved & tubular membrane structure
and is involved in hormone synthesis and the storage of Ca2+
ions Correct Answers Smooth ER

COP I vesicles mediate the transport of cargo from the
i)______________ to the ii)______________ Correct Answers
i) cis Golgi Network; ii) ER

COP II coat proteins mediate transport from the
i)______________ to the ii)______________ Correct Answers
i) ERES; ii) cis Golgi Network

COP II vesicles mediate i)______________ transport of cargo
ii)______________ Correct Answers i) anterograde; ii) from
the ER to the Golgi

,Defined by the presence of ribosomes attached to its cytosolic
surface, consist mostly of cisternae and is involved in protein
synthesis & processing Correct Answers Rough ER

during co-translational insert of integral membrane proteins into
the ER, the presence of + charged AAs upstream of the TMD
will result in the re-orientation of the polypeptide to Ncytosol-
Clumen orientation, this is referred to as _______________
Correct Answers The positive-outside rule

During N-linked glycosylation of oligosaccharide chain is added
to a/an i)_______________ functional grp w/in the R grp of the
ii)________________ in the N-X-S/T sequence Correct
Answers i) amide; ii) asparagine (N)

During the process of glycosylation i)______________ is an
enzyme which removes the terminal glucose residue from the
core oligosaccharide of a glycoprotein releasing it from the
membrane bound chaperone protein ii)______________ Correct
Answers i) Glucosidase II; ii) Calnexin

During the process of glycosylation i)_____________________
is the lipid carrier molecule to which sugar monomers are
sequentially added to form a/an ii)_____________________ that
will be transferred to a nascent protein in the production of
glycoproteins in the ER Correct Answers i) Dolichol phosphate;
ii) oligosaccharide chain

During the process the glycosylation i) ______________ is an
enzyme which removes the terminal glucose residue from the
core oligosaccharide of a glycoprotein releasing it from the

, membrane bound chaperone protein ii) ___________ Correct
Answers i) Glucosidase II; ii) Calnexin

ERAD is the process in which misfolded ER derived proteins
are poly-ubiquitinated & degraded by the proteasome. Where
does the protein degradation occur? Correct Answers In the
cytosol

function of nuclear envelope Correct Answers Regulates
transport in & out of the nucleus

function of nuclear Lamina Correct Answers Provides structural
support for the nucleus & serves as an attachment for chromatin
and the nuclear matrix

function of nuclear Matrix Correct Answers Maintains overall
shape of the nucleus & serves as a scaffold for nuclear
organization

functions of nuclear envelope? Correct Answers -to separates
the contents of the nucleus from the surround cytoplasm
(barrier). -provides the structural framework for the nucleus.

functions of nuclear matrix? Correct Answers structural role
and scaffold

Functions of the Golgi? Correct Answers -Protein transport; -
Protein & lipid modifications; -Final stages of N-linked
oligosaccharide