Chamberlain NR565 Pharm Midterm
Study online at https://quizlet.com/_eus27e
1. What Drugs can APRNs prescribe?: Schedule II - V in most states
2. Who determines and regulates prescriptive authority?: the jurisdiction of health profes-
sional board; State Board of Medicine etc.
3. How does limited prescriptive authority impact patients within the healthcare
system?: Longer wait times to sign a prescription; unequal relationships between providers
4. What are the key responsibilities of prescribing?: safe and competent practice understand-
ing of the drugs, reactions, and pharmacology;
Be aware of the age group you are prescribing to
Ex. Children vs older adults
5. What are some pharmacokinetic and pharmacodynamic changes of older
adults?: 1. Increased body fat
2. Decrease in lean mass
3. Decreased albumin
4. Decreased total body water
5. Decreased CO
6. Decreased GI absorption (less surface area, > pH, less GI motility, decreased gastric emptying)
7. Metabolism decreased by hepatic enzymes
8. Excretion impacted by renal blood flow, decreased GFR, lower number of nephrons
6. What baseline information is needed to prescribe for older adults based on
pharmacokinetics and dynamics?: Liver and renal labs;
Elderly have an enlarged liver, decreased blood flow to both liver and kidneys, and increased hepatic enzyme activity ...
drugs may have a longer half-life and prolonged effect
7. What is the Beer's Criteria?: Created by the American Geriatrics Society: A list created to help providers
decide what medications will be potentially inappropriate in the elderly population, heavily weighs the risks and
benefits.
8. Why is the Beer's Criteria important?: It provides a list of medications that are potentially harmfu
in elderly. List that identifies drugs with a high likelihood of causing adverse effects in older adults. Beers Criteria are
recommendations; ultimately prescribers must determine whether a medication is appropriate for use or not. These
guidelines are not intended to limit the use of medications or apply to all older adults. Safe and judicious prescribing
is crucial in the older adult to optimize pharmacotherapy.
9. Impacts and outcomes of polypharmacy: - drug interactions with mild side effects to life-threat-
ening consequences
, Chamberlain NR565 Pharm Midterm
Study online at https://quizlet.com/_eus27e
10. Examples of CYP450 inhibitors: "VISA Credit Card Debt inhibits spending on designers like CK to
look GQ"
Valproate
Isoniazid
Sulfonamides
Amiodarone
Chloramphenicol
Keotconazole
Grapefruit juice
Quinidine
11. What do CYP450 inhibitors do?: decrease rate of metabolism of another drug, so the drug will stick
around longer and have prolonged effects
12. What would CYP450 inhibitors cause if not used correctly?: dangerous toxic effects
or decreased therapeutic effect of drug
13. What are some examples of CYP450 inducers?: "BS CRAP GPS induces rage"
Barbituates
St. John Wort
Carbamazepine
Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbital
Sulonylureas
14. What do CYP450 inducers do?: Speed up metabolism of drugs (drug is cleared faster), drug has
lesser effect (decrease blood levels of drug), elevate CYP450 enzymes
15. What would the patient experience is a CYP450 inducer is not used correct-
ly?: Drug has a lessened or lower effect
16. What happens when someone has a poor metabolism phenotype?: substantially
decreased drug metabolism and, in particular situations, higher levels of drugs and increased risk for adverse drug
reactions
Study online at https://quizlet.com/_eus27e
1. What Drugs can APRNs prescribe?: Schedule II - V in most states
2. Who determines and regulates prescriptive authority?: the jurisdiction of health profes-
sional board; State Board of Medicine etc.
3. How does limited prescriptive authority impact patients within the healthcare
system?: Longer wait times to sign a prescription; unequal relationships between providers
4. What are the key responsibilities of prescribing?: safe and competent practice understand-
ing of the drugs, reactions, and pharmacology;
Be aware of the age group you are prescribing to
Ex. Children vs older adults
5. What are some pharmacokinetic and pharmacodynamic changes of older
adults?: 1. Increased body fat
2. Decrease in lean mass
3. Decreased albumin
4. Decreased total body water
5. Decreased CO
6. Decreased GI absorption (less surface area, > pH, less GI motility, decreased gastric emptying)
7. Metabolism decreased by hepatic enzymes
8. Excretion impacted by renal blood flow, decreased GFR, lower number of nephrons
6. What baseline information is needed to prescribe for older adults based on
pharmacokinetics and dynamics?: Liver and renal labs;
Elderly have an enlarged liver, decreased blood flow to both liver and kidneys, and increased hepatic enzyme activity ...
drugs may have a longer half-life and prolonged effect
7. What is the Beer's Criteria?: Created by the American Geriatrics Society: A list created to help providers
decide what medications will be potentially inappropriate in the elderly population, heavily weighs the risks and
benefits.
8. Why is the Beer's Criteria important?: It provides a list of medications that are potentially harmfu
in elderly. List that identifies drugs with a high likelihood of causing adverse effects in older adults. Beers Criteria are
recommendations; ultimately prescribers must determine whether a medication is appropriate for use or not. These
guidelines are not intended to limit the use of medications or apply to all older adults. Safe and judicious prescribing
is crucial in the older adult to optimize pharmacotherapy.
9. Impacts and outcomes of polypharmacy: - drug interactions with mild side effects to life-threat-
ening consequences
, Chamberlain NR565 Pharm Midterm
Study online at https://quizlet.com/_eus27e
10. Examples of CYP450 inhibitors: "VISA Credit Card Debt inhibits spending on designers like CK to
look GQ"
Valproate
Isoniazid
Sulfonamides
Amiodarone
Chloramphenicol
Keotconazole
Grapefruit juice
Quinidine
11. What do CYP450 inhibitors do?: decrease rate of metabolism of another drug, so the drug will stick
around longer and have prolonged effects
12. What would CYP450 inhibitors cause if not used correctly?: dangerous toxic effects
or decreased therapeutic effect of drug
13. What are some examples of CYP450 inducers?: "BS CRAP GPS induces rage"
Barbituates
St. John Wort
Carbamazepine
Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbital
Sulonylureas
14. What do CYP450 inducers do?: Speed up metabolism of drugs (drug is cleared faster), drug has
lesser effect (decrease blood levels of drug), elevate CYP450 enzymes
15. What would the patient experience is a CYP450 inducer is not used correct-
ly?: Drug has a lessened or lower effect
16. What happens when someone has a poor metabolism phenotype?: substantially
decreased drug metabolism and, in particular situations, higher levels of drugs and increased risk for adverse drug
reactions
