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1. what 3 labs are used for diagnosing thyroid dx: TSH
Free T4
Total 3
2. what is the time frame for rechecking labs after starting synthroid: 6-8 weeks after
initiation or dose adjustment
3. signs and symptoms of hypothyroidism: Fatigue, weight gain, cold intolerance, dry skin, hair
loss, constipation.
4. signs sand symptoms of hyperthyroidism: Weight loss
heat intolerance
anxiety
tremors
palpitations
increased appetite.
5. what medication treats thyroid storm: beta blockers
anti thyroid drugs(methimazole & PTU)
corticosteroids
fluids
6. what is the first line treatment for hyperthyroidism: Methimazole
7. what happens when hypothyroidism is not treated during pregnancy: increased
risk of miscarriage
pre term birth
developmental delays in child
8. what medication is used for treating hyperthyroid symptoms: beta blocks; propra-
nolol for tachycardia & tremors
9. what food/drugs interact with synthroid: Calcium and iron supplements (reduce absorption).
Soy products (may interfere with absorption).
Antacids & ppi (containing aluminum or magnesium).
coumadin & cathecholmines
, NR 565 Final exam
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10. what thyroid medication can be taken in the 1st trimester of pregnancy: PTU
(Propylthiouracil)
11. what thyroid treatment can be taken in 2nd & 3rd trimester of pregnancy: -
methimazole
12. what is a common side effect that warrants discontinuation of thyroid drug-
: agranulocytosis
13. what drug is used to treat hypothyroidism in infants & why is it important to
treat it: Synthroid- its important to treat early to prevent cognitive impairment
14. how is synthroid administered: its an oral drug that is taken on an empty stomach 30-60 mins before
breakfast
15. what are the adverse effects of synthroid: tachycardia, weight loss & anxiety
16. what lab is monitored when taking levothyroxine & how often: TSH level should be
checked every 6-8 weeks when initiating or adjust dose and then done annually
17. what is the MOA of Methimazole: Inhibits thyroid hormone synthesis by blocking the oxidation of
iodine.
18. what does an increase in TSH indicate: thyroid production is LOW
19. what 3 test confirm diabetes diagnosis: A1C e6.5%
Fasting Plasma Glucose (FPG) e126 mg/dL
Oral Glucose Tolerance Test (OGTT) e200 mg/dLA1C
20. when should insulin be considered: when A1C is >10% or if there are symptoms of hyperglycemia
21. at what time interval should glucose labs be rechecked: every 3 months until goal is
met and then every 6 months
22. how do you prevent diabetic nephropathy: Medications: ACE inhibitors or ARBs (renin-an-
giotensin system blockers).
Glycemic Control: Maintain HbA1c targets.
Blood Pressure Control: Goal of <140/90 mm Hg.
23. what is the action in insulin: Lowers blood glucose by facilitating cellular uptake of glucose into cells
and managing the bodys metabolism of fats, proteins and carbs.
24. pioglitazone is used to treat: diabetes
25. what are the contraindications of pioglitazone: heart failure
active bladder cancer
liver disease