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1. A pregnant patient with type 2 diabetes is considering using Exenatide (in-
cretinmimetics) for glycemic control. What advice should the healthcare pro-
vide give regarding Exenatide use during pregnancy?: Exenatide should be avoided during
pregnancy
2. Why is it necessary to demonstrate the administration of inhaled drugs to
patients?: To ensure proper usage
3. A pregnant woman in her second trimester seeks advice regarding the use of
dietary supplements. Which supplement should she avoid due to its potential
uterine stimulant effects?: Feverfew
4. Which adverse effect is commonly associated with probiotic use?: GI upset
5. A patient with renal impairment requires gout prophylaxis. Which medication
should be used with caution in this patient?: Allopurinol
6. What is the primary mechanism of action of loop diuretics like furosemide
leading to their diuretic effects?: Blockade of sodium and chloride reabsorption
7. A patient with moderate Crohn's disease is being considered for long-term
therapy. Which class of drugs would be most appropriate for this patient?: Im-
munosuppressants
8. Which medication is commonly used to relieve symptoms of mild to moderate
ulcerative colitis and Crohn's disease?: Sulfasalazine
9. Why is it challenging for drugs to reach sites of actions within the brain?: Pres-
ence of tight junctions in the blood-brain barrier
10. Why is blood flow to tissues considered a major factor in drug distribution?-
: Affects the delivery rate of drugs to tissues
11. A pregnant woman is experiencing chronic pain. What should the provider
consider regarding opioid use during pregnancy?: Opioids increase the risk of congenital
heart defects
12. What are the advantages of ACE inhibitors over thiazide diuretics in terms of
side effects related to potassium, uric acid, and glucose levels?: ACE inhibitors elevate
potassium levels but do not affect uric acid and glucose levels
13. What adverse effect is associated with the discontinuation of proton pump
inhibitors?: Rebound acid hypersecretion
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, NR 565 Final Exam questions (1)
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14. A patient presents with symptoms suggestive of IBS. Which herbal remedy is
recommended by the American College of Gastroenterology for management
of IBS based on randomized controlled trials?: Peppermint
15. A pregnant patient in the first trimester presents with hyperthyroidism
symptoms. What treatment option should the nurse practitioner consider?: -
Propylthiouracil (PTU)
16. Why are sulfonylureas ineffective in patients with type 1 diabetes?: Lack of insulin
synthesis
17. A patient describes a cycle of taking strong laxatives, experiencing purging
of their entire bowel, and then feeling convinced that constipation has returned
when they don't have a bowel movement for a few days. What is the most
appropriate initial step in managing this patient's current condition?: Gradually
tapering off laxative use over several weeks
18. When should replacement therapy for hypothyroidism in newborns ideally
be initiated?: Within the first week of birth
19. For patients with NSAID-induced ulcers, which of the following medications
is preferred for prophylactic therapy?: Proton pump inhibitors (PPI)
20. Which dietary supplement is generally well tolerated but may cause bad
breath and body odor as a common side effect?: Garlic
21. A patient on long-term warfarin therapy is considering adding a herbal
supplement into their regime. Which supplement should be avoided due to its
potential interaction with warfarin increasing the risk of bleeding?: Garlic
22. How is the selection of a specific NSAID for RA based?: Efficacy, safety, and cost
23. Why are highly lipid-soluble drugs absorbed more rapidly?: They cross membranes
easily
24. A 55-year-old postmenopausal woman seeks advice on managing her hot
flashes. She is interested in using soy supplements. What caution should be
given regarding the use of soy supplements in this patient?: Soy supplements can
increase the risk of developing breast cancer
25. What is the primary therapeutic goal of spironolactone when used in com-
bination with thiazide or loop diuretics?: Counteracting potassium wasting effects
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