WITH SOLVED QUESTIONS GRADED A+
◉ Haloperidol (Haldol). Answer: An FGA that blocks dopamine and has
additional blockade effects on acetylcholine, histamine, and
norepinephrine.
◉ Side Effects of FGAs. Answer: General: Sedation, orthostatic
hypotension; Anticholinergic: Dry mouth, blurred vision, constipation,
urinary retention.
◉ EPS: Acute Dystonia. Answer: Characterized by tongue/neck spasms.
◉ Pseudo-Parkinsonism. Answer: Symptoms include TRAP: Tremor,
Rigidity, Akinesia, Posture.
◉ Akathisia. Answer: Restless pacing.
◉ Tardive Dyskinesia. Answer: Involuntary worm-like movements of
the tongue/lips.
, ◉ Neuroleptic Malignant Syndrome (NMS). Answer: A life-threatening
condition with symptoms including fever, BP changes, rigidity, and
confusion.
◉ Nursing Teaching for FGAs. Answer: Monitor EPS/TD; treat acute
dystonia with Diphenhydramine/Benztropine; treat NMS by stopping the
medication and using Dantrolene and cooling blankets.
◉ Mnemonic for Haloperidol. Answer: "HAL's Crazy Dance Turns
Truly Awkward, Not Cool".
◉ Second Generation Antipsychotics (SGAs). Answer: Medications that
moderately block dopamine and strongly block serotonin, leading to
fewer EPS.
◉ Olanzapine (Zyprexa). Answer: An SGA with side effects including
sedation, orthostatic hypotension, dry mouth, and constipation.
◉ Metabolic Side Effects of SGAs. Answer: Includes weight gain,
diabetes, dyslipidemia, and increased heart risk.
◉ Nursing Teaching for SGAs. Answer: Encourage exercise and a
healthy diet; monitor weight, blood sugar, and lipids; report chest pain,
dyspnea, and tachycardia.