IMB 401 INTRO TO IMMUNE SYSTEM NOTES #1
Fights against infections (cancer) - correct answer - Normal
- Innate & adaptive immunity, B cell (Ab, humoral) and T cell (cellular response).
Vaccines to protect against infections diseases (tumors)
Overreaction - correct answer - Aberrant
- Hypersensitivity (allergy, asthma)
Loss of self-tolerance - correct answer - Aberrant
- Autoimmunity (lupus, type I diabetes)
Defective - correct answer - Aberrant
- Immune deficiency (SCID, AIDS)
Immune Rejection - correct answer - Normal
- Transplant rejection Graft vs Host disease
Immunity - correct answer Protective reaction against foreign particles such as
microorganisms or macromolecules. These substances are loosely referred to as
antigens (Ag)
Microorganisms - correct answer bacteria, fungi, & viruses
Macromolecules - correct answer proteins, polysaccharides, & nucleic acids
Antigen abbreviation - correct answer Ag
Immunogen - correct answer An antigen capable of evoking an immune response (e.g.
The production of antibodies)
Antibodies abbreviation - correct answer Ab
Immune System - correct answer The sum of molecules, cells and organs that are
involved in conferring immunity.
Immune Response - correct answer The sum of cellular and molecular events that
occur during exposure to foreign, immunogenic substances
Innate Immunity - correct answer That state of immunity with which one is born. It exists
regardless of exposure to antigen and is not enhanced by repeated exposure to antigen
, Adaptive Immunity- what type of cells? - correct answer T & B cells
Adaptive Immunity - correct answer State of immunity developed as a result of exposure
to an Ag. Highly specific for each antigen and enhanced by repeated exposure to same
Ag.
T Cells (Lymphocytes) - correct answer - One of the two main cell types of the adaptive
immune system (helper T cells, killer T cells and regulatory T cells).
- In charge of effecting and regulating the immune response.
- Can directly eliminate infectious organisms by stopping their regulation, or killing the
cells in which they replicate
- Help B cells make antibody and help stop the immune response (regulatory T cells,
Treg).
B Cells (Lymphocytes) - correct answer The other main cell type of the adaptive
immune system. Make antibodies that have numerous and potent anti-infection and
regulatory activities
Antibodies - correct answer - Also known as immunoglobulins are large Y-shaped
plasma proteins that bind to antigens to neutralize/destroy pathogens.
- Made by B cells in response to infection or immunization with antigen.
Immunoglobulins abbreviation - correct answer Ig
Antigen Presenting Cells (apcs) - correct answer Cells that capture antigen and present
them to T cells. Dendritic cells are the "professional" APC's able to stimulate new
immune responses; macrophages and B cells are "nonprofessional" apcs that can
support ongoing response
Dendrite Cells abbreviation - correct answer DC
Cluster of differentiation abbreviation - correct answer CD
Cluster of differentiation - correct answer System of immune molecule nomenclature
Molecules of the immune system - correct answer - Recognition molecules
- Activation molecules
- Trafficking molecules
- Elimination/effector molecules
Recognition molecules - correct answer T cell receptor, B cell receptor; Innate receptors
; MHC class I & II (present antigenic peptides to TCR)
Fights against infections (cancer) - correct answer - Normal
- Innate & adaptive immunity, B cell (Ab, humoral) and T cell (cellular response).
Vaccines to protect against infections diseases (tumors)
Overreaction - correct answer - Aberrant
- Hypersensitivity (allergy, asthma)
Loss of self-tolerance - correct answer - Aberrant
- Autoimmunity (lupus, type I diabetes)
Defective - correct answer - Aberrant
- Immune deficiency (SCID, AIDS)
Immune Rejection - correct answer - Normal
- Transplant rejection Graft vs Host disease
Immunity - correct answer Protective reaction against foreign particles such as
microorganisms or macromolecules. These substances are loosely referred to as
antigens (Ag)
Microorganisms - correct answer bacteria, fungi, & viruses
Macromolecules - correct answer proteins, polysaccharides, & nucleic acids
Antigen abbreviation - correct answer Ag
Immunogen - correct answer An antigen capable of evoking an immune response (e.g.
The production of antibodies)
Antibodies abbreviation - correct answer Ab
Immune System - correct answer The sum of molecules, cells and organs that are
involved in conferring immunity.
Immune Response - correct answer The sum of cellular and molecular events that
occur during exposure to foreign, immunogenic substances
Innate Immunity - correct answer That state of immunity with which one is born. It exists
regardless of exposure to antigen and is not enhanced by repeated exposure to antigen
, Adaptive Immunity- what type of cells? - correct answer T & B cells
Adaptive Immunity - correct answer State of immunity developed as a result of exposure
to an Ag. Highly specific for each antigen and enhanced by repeated exposure to same
Ag.
T Cells (Lymphocytes) - correct answer - One of the two main cell types of the adaptive
immune system (helper T cells, killer T cells and regulatory T cells).
- In charge of effecting and regulating the immune response.
- Can directly eliminate infectious organisms by stopping their regulation, or killing the
cells in which they replicate
- Help B cells make antibody and help stop the immune response (regulatory T cells,
Treg).
B Cells (Lymphocytes) - correct answer The other main cell type of the adaptive
immune system. Make antibodies that have numerous and potent anti-infection and
regulatory activities
Antibodies - correct answer - Also known as immunoglobulins are large Y-shaped
plasma proteins that bind to antigens to neutralize/destroy pathogens.
- Made by B cells in response to infection or immunization with antigen.
Immunoglobulins abbreviation - correct answer Ig
Antigen Presenting Cells (apcs) - correct answer Cells that capture antigen and present
them to T cells. Dendritic cells are the "professional" APC's able to stimulate new
immune responses; macrophages and B cells are "nonprofessional" apcs that can
support ongoing response
Dendrite Cells abbreviation - correct answer DC
Cluster of differentiation abbreviation - correct answer CD
Cluster of differentiation - correct answer System of immune molecule nomenclature
Molecules of the immune system - correct answer - Recognition molecules
- Activation molecules
- Trafficking molecules
- Elimination/effector molecules
Recognition molecules - correct answer T cell receptor, B cell receptor; Innate receptors
; MHC class I & II (present antigenic peptides to TCR)
