IMMUNOLOGY – EXAM QUESTIONS AND ANSWERS 2025-
26 #16
Contact with the oils from poison ivy leaves results in chemically-altered human proteins
that activate T cells. The resulting irritation and tissue damage is mostly the result of:
A. Immediate release of high-affinity igg by B cells.
B. T cells and macrophages destroying cells that present altered peptides.
C. Degranulation of mast cells carrying ige against poison ivy.
D. Complement proteins attacking the plant oil molecules. - correct answer B. T cells
and macrophages destroying cells that present altered peptides.
Why are Type I allergies (such as against flower pollen and bee stings) called
immediate hypersensitivities?
A. Because Type I allergens induce strong immune responses that do not depend on
elements of adaptive immunity.
B. Because hypersensitivity to these specific allergens are encoded in our genes.
C. Because binding & cross-linking of antigen-specific ige on mast cells leads to very
fast release of inflammatory molecules.
D. Because these allergic responses can be treated by immediately taking antihistamine
drugs. - correct answer C. Because binding & cross-linking of antigen-specific ige on
mast cells leads to very fast release of inflammatory molecules.
Which of the following is true about igg4?
A. Activated B cells normally express igg4 before switching to ige.
B. Igg4 has the weakest antigen-binding specificity of all Ig types.
C. Igg4 light/heavy chains typically have the fewest number of somatic hyper-mutations
compared to other igg types.
D. Igg4 can suppress cytokine production by macrophages as part of shifting immune
response away from inflammation. - correct answer D. Igg4 can suppress cytokine
production by macrophages as part of shifting immune response away from
inflammation.
What is true about ige bound to fcεri on a mast cell?
26 #16
Contact with the oils from poison ivy leaves results in chemically-altered human proteins
that activate T cells. The resulting irritation and tissue damage is mostly the result of:
A. Immediate release of high-affinity igg by B cells.
B. T cells and macrophages destroying cells that present altered peptides.
C. Degranulation of mast cells carrying ige against poison ivy.
D. Complement proteins attacking the plant oil molecules. - correct answer B. T cells
and macrophages destroying cells that present altered peptides.
Why are Type I allergies (such as against flower pollen and bee stings) called
immediate hypersensitivities?
A. Because Type I allergens induce strong immune responses that do not depend on
elements of adaptive immunity.
B. Because hypersensitivity to these specific allergens are encoded in our genes.
C. Because binding & cross-linking of antigen-specific ige on mast cells leads to very
fast release of inflammatory molecules.
D. Because these allergic responses can be treated by immediately taking antihistamine
drugs. - correct answer C. Because binding & cross-linking of antigen-specific ige on
mast cells leads to very fast release of inflammatory molecules.
Which of the following is true about igg4?
A. Activated B cells normally express igg4 before switching to ige.
B. Igg4 has the weakest antigen-binding specificity of all Ig types.
C. Igg4 light/heavy chains typically have the fewest number of somatic hyper-mutations
compared to other igg types.
D. Igg4 can suppress cytokine production by macrophages as part of shifting immune
response away from inflammation. - correct answer D. Igg4 can suppress cytokine
production by macrophages as part of shifting immune response away from
inflammation.
What is true about ige bound to fcεri on a mast cell?
