NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
Prescribing basics - correct answer Prescribing is regulated by state BON
Proper RX - correct answer Providers name and address, Telephone
DEA
Pt name/DOB/Addres
Name of Drug, strength, SIG(directions) with indication/Route and frequency,
Quantity and signature.
Drug Schedules: Most addictive to least - correct answer 1: Heroin,LSD, MJ
2: hydrocodone, cocaine, Methamphetamine, methadone, oxycodone, meperidine,
fentanyl, adderall, ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol
5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics - correct answer The effects of drug on the body. Receptors are
large molecules usually proteins, that interact and mediate the action of drugs
agonist - correct answer produce receptor stimulation and a conformational change
every time they bind. Do not need all available receptors to produce a maximum
response
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
Partial agonist - correct answer drugs that have properties in b/w those of full
agonist and antagonist. They bind to receptors but when they occupy the receptor
sites, they stimulate only some of the receptors.
antagonist - correct answer drugs with affinity for a receptor but with no intrinsic
activity. Affinity allows the antagonist to bind to receptors, but lack of intrinsic
activity prevents the bound antagonist from causing receptor activation. The block
action of drugs (ex. Narcan)
Bioavailabity - correct answer % of administered dosage of the drug that survives the
first pass through the liver and reaches the blood stream
half life - correct answer Time required for the amount of a drug in the body to
decline by 50%, drugs with shorter half lives must be administer frequently. 4.5-5.5
times the half life to get steady state and to be limited from the body
what the body does to the drug - correct answer absorption, distribution,
metabolism, excretion
Distribution - correct answer movement of absorbed drug in bodily fluids
throughout the body to target tissue. Properties affecting: lipid/water solubility, PH
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
affects ionization of drug, protein binding, size of molecule (smaller molecules are
more able to diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid soluble will pass), placental barrier
(many drugs can pass)
Protein binding - correct answer unbound drug is free which is active, crosses
membrane. Low plasma proteins result in more free drug. Competition: when 2 highly
bound drugs are given it increases the level of both drugs
Metabolism - correct answer take place in the liver mostly. Chemical change of a
drug structure to:
Enhance excretion, inactivate the drug, increase therapeutic action, active a prodrug
(inactive until metabolized in the body into the active compound, ex: levodopa),
increase or decrease toxicity
CYP450 - correct answer enzymes constitutes the most important of the phase I
metabolizing enzymes (account for about 75% of drug metabolism in the liver)
Phase 2: conjugation reaction occur leading to large increases in hydrophilicity of the
substrates rendering them more readily excretable
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
Substrate - correct answer an agent that is metabolized by an enzyme into a
metabolite and product and eventually excreted
Inhibitors - correct answer compete with other drugs for a particular enzyme
affecting the metabolism (decreased) of the substrate and decreases the excretion of
the substrate and increasing the circulating drug
inducer - correct answer competes with other drugs for a particular enzyme affecting
metabolism of the substrate (increases) decreasing the efficacy of the drug
excretion - correct answer renal: passive glomerular filtration, active tubular
secretion, tubular reabsorption, gi tract, lung, sweat and salivary, mammary
genomics - correct answer study of the complete set of genetic information present
in a cell, an organism, or species
pharmacogenetics - correct answer the study of the influence of hereditary factors
on the response of individual organisms to drugs, and the study of variations of DNA
and RNA characteristics as related to drug response
Pharmacogenetics tests - correct answer Mentioned on drug labels can be classified
as "test required," "test recommended," and "information only." Currently, four drugs
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
Prescribing basics - correct answer Prescribing is regulated by state BON
Proper RX - correct answer Providers name and address, Telephone
DEA
Pt name/DOB/Addres
Name of Drug, strength, SIG(directions) with indication/Route and frequency,
Quantity and signature.
Drug Schedules: Most addictive to least - correct answer 1: Heroin,LSD, MJ
2: hydrocodone, cocaine, Methamphetamine, methadone, oxycodone, meperidine,
fentanyl, adderall, ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol
5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics - correct answer The effects of drug on the body. Receptors are
large molecules usually proteins, that interact and mediate the action of drugs
agonist - correct answer produce receptor stimulation and a conformational change
every time they bind. Do not need all available receptors to produce a maximum
response
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
Partial agonist - correct answer drugs that have properties in b/w those of full
agonist and antagonist. They bind to receptors but when they occupy the receptor
sites, they stimulate only some of the receptors.
antagonist - correct answer drugs with affinity for a receptor but with no intrinsic
activity. Affinity allows the antagonist to bind to receptors, but lack of intrinsic
activity prevents the bound antagonist from causing receptor activation. The block
action of drugs (ex. Narcan)
Bioavailabity - correct answer % of administered dosage of the drug that survives the
first pass through the liver and reaches the blood stream
half life - correct answer Time required for the amount of a drug in the body to
decline by 50%, drugs with shorter half lives must be administer frequently. 4.5-5.5
times the half life to get steady state and to be limited from the body
what the body does to the drug - correct answer absorption, distribution,
metabolism, excretion
Distribution - correct answer movement of absorbed drug in bodily fluids
throughout the body to target tissue. Properties affecting: lipid/water solubility, PH
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
affects ionization of drug, protein binding, size of molecule (smaller molecules are
more able to diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid soluble will pass), placental barrier
(many drugs can pass)
Protein binding - correct answer unbound drug is free which is active, crosses
membrane. Low plasma proteins result in more free drug. Competition: when 2 highly
bound drugs are given it increases the level of both drugs
Metabolism - correct answer take place in the liver mostly. Chemical change of a
drug structure to:
Enhance excretion, inactivate the drug, increase therapeutic action, active a prodrug
(inactive until metabolized in the body into the active compound, ex: levodopa),
increase or decrease toxicity
CYP450 - correct answer enzymes constitutes the most important of the phase I
metabolizing enzymes (account for about 75% of drug metabolism in the liver)
Phase 2: conjugation reaction occur leading to large increases in hydrophilicity of the
substrates rendering them more readily excretable
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
Substrate - correct answer an agent that is metabolized by an enzyme into a
metabolite and product and eventually excreted
Inhibitors - correct answer compete with other drugs for a particular enzyme
affecting the metabolism (decreased) of the substrate and decreases the excretion of
the substrate and increasing the circulating drug
inducer - correct answer competes with other drugs for a particular enzyme affecting
metabolism of the substrate (increases) decreasing the efficacy of the drug
excretion - correct answer renal: passive glomerular filtration, active tubular
secretion, tubular reabsorption, gi tract, lung, sweat and salivary, mammary
genomics - correct answer study of the complete set of genetic information present
in a cell, an organism, or species
pharmacogenetics - correct answer the study of the influence of hereditary factors
on the response of individual organisms to drugs, and the study of variations of DNA
and RNA characteristics as related to drug response
Pharmacogenetics tests - correct answer Mentioned on drug labels can be classified
as "test required," "test recommended," and "information only." Currently, four drugs
