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NUR 2092 Chapter 11 Exam – 100 Questions on Antifungal Drugs, Systemic Infections & Azole Safety – Chamberlain

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This NCLEX-focused review for NUR 2092: Nursing Pharmacology at Chamberlain University includes 100 expertly formulated questions and answers, covering Chapter 11 – Antifungal Agents. Developed for the 2025/2026 academic year, this resource prepares students to understand the mechanisms, indications, and nursing implications of antifungal medications in both systemic and topical use. The questions reflect clinical judgment scenarios and foundational knowledge expected in nursing pharmacology. They cover multiple antifungal classes and common clinical infections such as candidiasis, onychomycosis, tinea infections, aspergillosis, and cryptococcosis. Key topics include: Azoles (fluconazole, ketoconazole, posaconazole): usage, contraindications (e.g., liver disease, pregnancy), and drug interactions (e.g., with warfarin, ergot) Polyenes (amphotericin B): nephrotoxicity, IV administration, infusion-related reactions (fever, chills), and electrolyte monitoring Echinocandins (caspofungin, micafungin, anidulafungin): use in systemic infections and hepatotoxicity monitoring Topical antifungals: nystatin, miconazole, naftifine – application safety, skin irritation, and patient teaching Fungal infection assessment: risk groups (AIDS, transplant patients, elderly), signs of liver dysfunction, and medication education Nursing responsibilities: client teaching on contraception, liver enzyme monitoring (AST/ALT), LFTs, creatinine clearance, and safe administration of vaginal antifungal agents The document emphasizes both NCLEX-style questions and clinical teaching points, making it a vital resource for exam readiness and safe nursing practice in infection control and medication management. Recommended for: Students enrolled in NUR 2092 at Chamberlain University Nursing students preparing for pharmacology exams, NCLEX-RN, or ATI infection control and antifungal drug modules Learners managing patients on azole, polyene, or echinocandin therapy in clinical rotations Allied health students studying systemic vs. topical fungal infection treatments and nursing actions This comprehensive Q&A set builds essential pharmacological confidence in handling fungal disease management. Keywords: NUR 2092, Chapter 11, antifungal agents, fluconazole, amphotericin B, ketoconazole, caspofungin, micafungin, echinocandins, nystatin, LFT monitoring, fungal infections, candidiasis, hepatotoxicity, antifungal drug interactions, NCLEX pharmacology, Chamberlain

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NUR 2092 Pharmacology Ch - 11
Antifungal Agents Questions and
Answers

An older adult client has been diagnosed with candidiasis and prescribed

fluconazole. What aspect of the client's health status should warrant close

monitoring by the nurse? - 🧠 ANSWER ✔✔The client has atrial fibrillation

and takes warfarin daily

A parent has informed the nurse that she has been applying an over the

counter antifungal to her infant's buttocks and perineal region for a rash.

What question related to safety should the nurse ask the parent? - 🧠

ANSWER ✔✔"Are there any open wounds on the areas where you're

putting the ointment?"

,Which drug is most commonly used orally to treat infections caused by

Candida albicans? - 🧠 ANSWER ✔✔Fluconazole (Diflucan)


An adult client has begun treatment with fluconazole. The nurse should

recognize the need to likely discontinue the drug if the client develops

which sign or symptom? - 🧠 ANSWER ✔✔Jaundice


The nurse is caring for a client who has been prescribed micafungin, 150

mg IV daily. What assessment should the nurse prioritize in this client's

care? - 🧠 ANSWER ✔✔Inspection of the client's mouth and throat


A nurse is instructing a 19-year-old female patient on the use of fluconazole

for candida vaginitis. A teaching priority will be to: - 🧠 ANSWER ✔✔use an

alternative form of birth control, if taking an oral contraceptive.

An adult client, recently diagnosed with a tinea infection, has begun

treatment with griseofulvin. During a scheduled clinic visit, the client states

to the nurse, "I'm pretty good at reading my body's signals, so I make sure

to take a bit extra when I think my infection is getting worse." This client's

statement is suggestive of what nursing diagnosis? - 🧠 ANSWER

✔✔deficient knowledge related to correct use of griseofulvin

, A client has been placed on amphotericin B. The nurse caring for this client

should administer this medication: - 🧠 ANSWER ✔✔intravenously.


A client has been prescribed a topical antifungal ointment to treat a fungal

infection between her breasts. When providing education about this

medication, the nurse should encourage the client to: - 🧠 ANSWER

✔✔wash and dry the affected area before applying the ointment.


A client with a fungal infection has been prescribed a miconazole vaginal

suppository. What education should the nurse provide about safe and

effective administration? - 🧠 ANSWER ✔✔"If possible, lie down for 10 or 15

minutes after inserting the medication."

The client is receiving ketoconazole. The nurse should be concerned about

a drug-drug interaction on the basis of what other comorbidity? - 🧠

ANSWER ✔✔Type 2 diabetes


The nurse is caring for a client diagnosed with a life-threatening systemic

fungal infection that is not responding to treatment with an azole. What

medication should the nurse anticipate the provider may order next? - 🧠

ANSWER ✔✔Amphotericin B




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