NR546 PSYCHOPHARM MIDTERM || 117
QUESTIONS AND ANSWERS (GRADED
A+)
How does the orbitofrontal cortex (OFC) affect the amygdala? - ANSWER-inhibits and
activates the amygdala
Wernicke's area is associated with which of the following? - ANSWER-speech
comprehension
The limbic system is associated with which of the following - ANSWER-emotion and
learning
Which brain structure is most associated with long term memory? - ANSWER-
hippocampus
When prescribing psychotropic medications, the PMHNP knows that these medications
work within which specific areas? - ANSWER-mood
Which of the following are involved in regulating neurotransmission via excitation-
secretion coupling? - ANSWER-voltage-sensitive sodium channels and voltage-
sensitive calcium channels
What system influences the length of time for a drug to achieve efficacy? - ANSWER-
signal transduction cascades
One of the signal transduction cascades, pass the message from a first receptor to a
second messenger. - ANSWER-G protein linked systems
What area of the brain is associated with negative and affective symptoms? -
ANSWER-Mesocortical and ventromedial prefrontal cortex:
What area of the brain is associated with cognitive symptoms? - ANSWER-Dorsolateral
What area of the brain is associated with aggressive, impulsive symptoms? - ANSWER-
Orbitofrontal and connections to the amygdala
Non-selectively blocks dopamine D2 receptors, specifically in mesolimbic pathway.
Improves Positive Symptoms
Use: Acute & Chronic Schizophrenia & Psychosis - ANSWER-First generation
antipsychotics
, Human central nervous system communication at synapses is which of the following? -
ANSWER-chemical
Which of the following is an excitatory neurotransmitter? - ANSWER-glutamate
Which statement correctly pairs the pharmacodynamic effect with its definition? -
ANSWER-antagonist effect - drug binds to receptor, but does not activate a response
A major current hypothesis for the cause of schizophrenia proposes that N-methyl-d-
aspartate (NMDA) receptors may be which of the following?
Correct! - ANSWER-hypofunctional
Which medication is least associated with weight gain? - ANSWER-aripiprazole
Which dopamine pathway is associated with positive symptoms of schizophrenia? -
ANSWER-mesolimbic pathway
Which pathway is associated with negative symptoms? - ANSWER-The mesocortical
pathway
Is part of the extrapyramidal nervous system and associated with extrapyramidal
symptoms (EPS) - ANSWER-nigrostriatal pathway
This pathway is associated with hyperprolactinemia. - ANSWER-The tuberoinfundibular
pathway
A 34-year old male recently began experiencing breast secretions while receiving
risperidone . Which dopamine pathway is associated with this side effect? - ANSWER-
tuberoinfundibular pathway
A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of
schizophrenia. Regarding affinity, atypical antipsychotics demonstrate which of the
following most often? - ANSWER-Atypical antipsychotics have equal positive symptom
antipsychotic actions and low extrapyramidal symptoms.
is a syndrome that can be associated with several different psychiatric disorders.
Symptoms include hallucinations, delusions, disorganized speech, disorganized
behavior, and distortions of reality. This syndrome can affect a person's cognition,
affective response, communication, capacity to recognize reality, and ability to relate to
others. - ANSWER-psychosis
What Diagnosis require the presence of psychosis? - ANSWER-schizophrenia
substance-induced psychotic disorders
schizophreniform disorder
QUESTIONS AND ANSWERS (GRADED
A+)
How does the orbitofrontal cortex (OFC) affect the amygdala? - ANSWER-inhibits and
activates the amygdala
Wernicke's area is associated with which of the following? - ANSWER-speech
comprehension
The limbic system is associated with which of the following - ANSWER-emotion and
learning
Which brain structure is most associated with long term memory? - ANSWER-
hippocampus
When prescribing psychotropic medications, the PMHNP knows that these medications
work within which specific areas? - ANSWER-mood
Which of the following are involved in regulating neurotransmission via excitation-
secretion coupling? - ANSWER-voltage-sensitive sodium channels and voltage-
sensitive calcium channels
What system influences the length of time for a drug to achieve efficacy? - ANSWER-
signal transduction cascades
One of the signal transduction cascades, pass the message from a first receptor to a
second messenger. - ANSWER-G protein linked systems
What area of the brain is associated with negative and affective symptoms? -
ANSWER-Mesocortical and ventromedial prefrontal cortex:
What area of the brain is associated with cognitive symptoms? - ANSWER-Dorsolateral
What area of the brain is associated with aggressive, impulsive symptoms? - ANSWER-
Orbitofrontal and connections to the amygdala
Non-selectively blocks dopamine D2 receptors, specifically in mesolimbic pathway.
Improves Positive Symptoms
Use: Acute & Chronic Schizophrenia & Psychosis - ANSWER-First generation
antipsychotics
, Human central nervous system communication at synapses is which of the following? -
ANSWER-chemical
Which of the following is an excitatory neurotransmitter? - ANSWER-glutamate
Which statement correctly pairs the pharmacodynamic effect with its definition? -
ANSWER-antagonist effect - drug binds to receptor, but does not activate a response
A major current hypothesis for the cause of schizophrenia proposes that N-methyl-d-
aspartate (NMDA) receptors may be which of the following?
Correct! - ANSWER-hypofunctional
Which medication is least associated with weight gain? - ANSWER-aripiprazole
Which dopamine pathway is associated with positive symptoms of schizophrenia? -
ANSWER-mesolimbic pathway
Which pathway is associated with negative symptoms? - ANSWER-The mesocortical
pathway
Is part of the extrapyramidal nervous system and associated with extrapyramidal
symptoms (EPS) - ANSWER-nigrostriatal pathway
This pathway is associated with hyperprolactinemia. - ANSWER-The tuberoinfundibular
pathway
A 34-year old male recently began experiencing breast secretions while receiving
risperidone . Which dopamine pathway is associated with this side effect? - ANSWER-
tuberoinfundibular pathway
A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of
schizophrenia. Regarding affinity, atypical antipsychotics demonstrate which of the
following most often? - ANSWER-Atypical antipsychotics have equal positive symptom
antipsychotic actions and low extrapyramidal symptoms.
is a syndrome that can be associated with several different psychiatric disorders.
Symptoms include hallucinations, delusions, disorganized speech, disorganized
behavior, and distortions of reality. This syndrome can affect a person's cognition,
affective response, communication, capacity to recognize reality, and ability to relate to
others. - ANSWER-psychosis
What Diagnosis require the presence of psychosis? - ANSWER-schizophrenia
substance-induced psychotic disorders
schizophreniform disorder
