2026/2027 | COMPLETE MASTER REVIEW | GRADED A+ | 100%
CORRECT | VERIFIED STUDY SET FOR GUARANTEED SUCCESS |
HIGH-YIELD CONCEPTS, ADVANCED NURSING & CLINICAL
APPLICATION INSIGHTS FOR EXCELLENCE
Transcription is the process by which RNA is synthesized from a DNA
template. The correct option is the only one that accurately defines the term
transcription.
What is the purpose of using a Giemsa staining technique on chromosomes?
a.
Permit the mitotic process to be followed and monitored for variations.
b.
Allow for the numbering of chromosomes and the identification of variations.
c.
Identify new somatic cells formed through mitosis and cytokinesis.
d.
Distinguish the sex chromosomes from the homologous chromosomes. -
CORRECT ANSWER - ANS: B
One of the most commonly used stains is Giemsa stain. By using banding
techniques, chromosomes can be unambiguously numbered, and individual
variation in chromosome composition can be studied. Missing or duplicated
portions of chromosomes, which often result in serious diseases, also can be
readily identified. The correct option is the only one that accurately describes
the purpose of the Giemsa staining technique.
An amniocentesis indicates a neural tube defect when an increase in which
protein is evident?
a.
Cytochrome P-450
b.
,Alpha fetoprotein
c.
DNA polymerase
d.
Embryonic proteins - CORRECT ANSWER - ANS: B
Other disorders can be detected with this procedure. These include most neural
tube defects, which cause an elevation of alpha fetoprotein in the amniotic fluid,
and hundreds of diseases caused by mutations of single genes. Cytochrome P-
450 is useful in helping to formulate drug doses more precisely. DNA
polymerase travels along the single DNA strand, adding the correct nucleotides
to the free end of the new strand during DNA replication. Embryonic proteins
are not involved in neural tube defects.
Amniocentesis is recommended for pregnant with what history?
a.
Have a history of chronic illness
b.
Have a family history of genetic disorders
c.
Have experienced in vitro fertilization
d.
Had a late menarche - CORRECT ANSWER - ANS: B
In somatic cell gene therapy, what type of vector is most commonly used to
alter a specific set of an individual's somatic cells?
a.
Virus
b.
Bacteria
c.
,RNA polymerase
d.
Recombinant DNA - CORRECT ANSWER - ANS: A
In somatic cell gene therapy, a vector is used to carry a normal copy of the
mutated gene into the individual's cells. These vectors are usually viruses, such
as retroviruses, lentiviruses, or adenoviruses, which have been genetically
modified so that they contain the normal human gene and cannot make copies
of themselves (otherwise they could cause a viral infection). Bacteria, RNA
polymerase, and recombinant DNA are not used as vectors in somatic cell gene
therapy.
In DNA replication, what does the enzyme DNA polymerase do?
a.
Travel along the single DNA strand, adding the correct nucleotide to the new
strand
b.
Move along the double strand of DNA to unwind the nucleotides of the double
helix
c.
Hold the double strand apart while the correct nucleotides are added to the
strand
d.
Transport the double strand of DNA from the nucleus to the cytoplasm for
protein formation - CORRECT ANSWER - ANS: A
The DNA polymerase enzyme travels along the single DNA strand, adding the
correct nucleotides to the free end of the new strand (see Figure 4-3, B). The
correct option is the only one that accurately describes the process involved in
DNA replication using DNA polymerase.
How is transcription best defined?
a.
, DNA polymerase binds to the promoter site on ribonucleic acid (RNA).
b.
RNA directs the synthesis of polypeptides for protein synthesis.
c.
RNA is synthesized from a DNA template.
d.
A base pair substitution results in a mutation of the amino acid sequence. -
CORRECT ANSWER - ANS: C
Amniocentesis is recommended only for pregnancies known to have an elevated
risk for a genetic disease or in women older than 30 to 35 years of age because
of the slightly higher risk of fetal loss as compared to the general population.
Having a chronic illness, previous in vitro fertilization, or late menarche are not
reasons to have an amniocentesis.
What is the technique for prenatal diagnosis of chromosomal abnormalities at
10 to 12 weeks' gestation?
a.
Gene mapping
b.
Linkage analysis
c.
Amniocentesis
d.
Chorionic villus sampling - CORRECT ANSWER - ANS: D
Chorionic villus sampling consists of extracting a small amount of villous tissue
directly from the chorion. This procedure can be performed at 10 weeks'
gestation and does not require in vitro culturing of cells; sufficient numbers are
directly available in the extracted tissue. Thus the procedure allows prenatal
diagnosis at approximately 3 months' gestation rather than at nearly 4 months'
gestation which is generally when amniocentesis is performed. Gene mapping