1|Page
NURS 5354 EXAM 3 CONTENT COMPLETELY
UPDATED 2025–2026 EDITION | VERIFIED
QUESTIONS & 100% ACCURATE ANSWERS |
GUARANTEED A+ PERFORMANCE
What is the mechanism of action for local anesthetics?
suppress pain by blocking sodium channels and blocking impulse conductions
along axons.
What is the warning for using topical benzocaine?
It causes methemoglobinemia in children less than 2 years.
What is methemoglobinemia?
Hgb is modified and cannot release oxygen to tissues and is converted into mthgb;
if enough Hgb is converted can lead to death
What are the other topical anesthetics?
Lidocaine
Cocaine
Tetracaine
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Dyclonine
Adverse effects of local anesthetics
CNS excitation followed by depression
CV - bradycardia, heart block, reduced contractility, cardiac arrest, hypotension
Allergic Reactions
Methemoglobinemia - BENZOCAINE SPECIFICALLY
Prototype
an individual drug that represents a drug class - group of meds that have a similar
chemical structure and MOA
Opioid receptors
u (mu) and k (kappa)
MU receptor activation
activation of receptor causes respiratory depression, euphoria, sedation, suppress
bowel motility
, 3|Page
Kappa receptor activation
activation produces analgesia and sedation
What is the prototype for measuring opioids?
morphine is the prototype of the strong opioids and remains the standard by which
newer opioids are measured
Opioid classes
pure agonists
partical agonist + agonist/antagonist
pure antagonist
Pure Agonists
morphine
fentanyl - hydromorphone, methadone, meperidine, sufentanil
NURS 5354 EXAM 3 CONTENT COMPLETELY
UPDATED 2025–2026 EDITION | VERIFIED
QUESTIONS & 100% ACCURATE ANSWERS |
GUARANTEED A+ PERFORMANCE
What is the mechanism of action for local anesthetics?
suppress pain by blocking sodium channels and blocking impulse conductions
along axons.
What is the warning for using topical benzocaine?
It causes methemoglobinemia in children less than 2 years.
What is methemoglobinemia?
Hgb is modified and cannot release oxygen to tissues and is converted into mthgb;
if enough Hgb is converted can lead to death
What are the other topical anesthetics?
Lidocaine
Cocaine
Tetracaine
,2|Page
Dyclonine
Adverse effects of local anesthetics
CNS excitation followed by depression
CV - bradycardia, heart block, reduced contractility, cardiac arrest, hypotension
Allergic Reactions
Methemoglobinemia - BENZOCAINE SPECIFICALLY
Prototype
an individual drug that represents a drug class - group of meds that have a similar
chemical structure and MOA
Opioid receptors
u (mu) and k (kappa)
MU receptor activation
activation of receptor causes respiratory depression, euphoria, sedation, suppress
bowel motility
, 3|Page
Kappa receptor activation
activation produces analgesia and sedation
What is the prototype for measuring opioids?
morphine is the prototype of the strong opioids and remains the standard by which
newer opioids are measured
Opioid classes
pure agonists
partical agonist + agonist/antagonist
pure antagonist
Pure Agonists
morphine
fentanyl - hydromorphone, methadone, meperidine, sufentanil
