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NURS 5354 FINAL EXAM PRACTICE
COMPLETELY UPDATED 2025–2026 EDITION |
VERIFIED QUESTIONS & 100% ACCURATE
ANSWERS | GUARANTEED A+ PERFORMANCE
SECTION 1: Pharmacokinetics, Pharmacodynamics, and Prescribing
Principles
1. The term bioavailability refers to:
A. The percentage of a drug bound to plasma proteins
B. The proportion of a drug that reaches systemic circulation unchanged
C. The rate at which a drug is metabolized by the liver
D. The drug’s distribution half-life
- ANSWER: B
2. Which pharmacokinetic phase involves drug absorption, distribution,
metabolism, and excretion?
A. Pharmacodynamics
B. Pharmacokinetics
C. Drug tolerance
D. Homeostasis
- ANSWER: B
3. The first-pass effect most affects which route of drug administration?
A. Sublingual
B. Oral
C. Intravenous
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D. Transdermal
- ANSWER: B
4. A drug with a narrow therapeutic index requires:
A. Once-a-day dosing
B. Therapeutic drug monitoring
C. No dosage adjustment
D. Food co-administration
- ANSWER: B
5. Cytochrome P450 inducers such as rifampin and phenytoin will:
A. Increase drug levels
B. Decrease drug metabolism
C. Increase drug metabolism and reduce efficacy
D. Inhibit hepatic clearance
- ANSWER: C
6. The drug half-life represents:
A. Time required to achieve peak concentration
B. Time required for plasma concentration to fall by 50%
C. Time to reach steady-state
D. Duration of pharmacologic effect
- ANSWER: B
7. Steady state is reached after approximately how many half-lives?
A. 1
B. 2
C. 4–5
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D. 10
- ANSWER: C
8. A competitive antagonist:
A. Enhances receptor activation
B. Competes with agonists for receptor sites
C. Irreversibly binds to receptors
D. Reduces bioavailability
- ANSWER: B
9. The Beers Criteria is primarily used to:
A. Identify pediatric dosing guidelines
B. Guide antibiotic stewardship
C. Prevent inappropriate prescribing in older adults
D. Standardize prescribing in hospitals
- ANSWER: C
10. Drug bioequivalence between generics and brand names is defined by:
A. FDA safety rating
B. Similarity in pharmacologic class
C. Equivalent rate and extent of absorption
D. Similar price
- ANSWER: C
❤️ SECTION 2: Cardiovascular & Renal Pharmacology
NURS 5354 FINAL EXAM PRACTICE
COMPLETELY UPDATED 2025–2026 EDITION |
VERIFIED QUESTIONS & 100% ACCURATE
ANSWERS | GUARANTEED A+ PERFORMANCE
SECTION 1: Pharmacokinetics, Pharmacodynamics, and Prescribing
Principles
1. The term bioavailability refers to:
A. The percentage of a drug bound to plasma proteins
B. The proportion of a drug that reaches systemic circulation unchanged
C. The rate at which a drug is metabolized by the liver
D. The drug’s distribution half-life
- ANSWER: B
2. Which pharmacokinetic phase involves drug absorption, distribution,
metabolism, and excretion?
A. Pharmacodynamics
B. Pharmacokinetics
C. Drug tolerance
D. Homeostasis
- ANSWER: B
3. The first-pass effect most affects which route of drug administration?
A. Sublingual
B. Oral
C. Intravenous
,2|Page
D. Transdermal
- ANSWER: B
4. A drug with a narrow therapeutic index requires:
A. Once-a-day dosing
B. Therapeutic drug monitoring
C. No dosage adjustment
D. Food co-administration
- ANSWER: B
5. Cytochrome P450 inducers such as rifampin and phenytoin will:
A. Increase drug levels
B. Decrease drug metabolism
C. Increase drug metabolism and reduce efficacy
D. Inhibit hepatic clearance
- ANSWER: C
6. The drug half-life represents:
A. Time required to achieve peak concentration
B. Time required for plasma concentration to fall by 50%
C. Time to reach steady-state
D. Duration of pharmacologic effect
- ANSWER: B
7. Steady state is reached after approximately how many half-lives?
A. 1
B. 2
C. 4–5
, 3|Page
D. 10
- ANSWER: C
8. A competitive antagonist:
A. Enhances receptor activation
B. Competes with agonists for receptor sites
C. Irreversibly binds to receptors
D. Reduces bioavailability
- ANSWER: B
9. The Beers Criteria is primarily used to:
A. Identify pediatric dosing guidelines
B. Guide antibiotic stewardship
C. Prevent inappropriate prescribing in older adults
D. Standardize prescribing in hospitals
- ANSWER: C
10. Drug bioequivalence between generics and brand names is defined by:
A. FDA safety rating
B. Similarity in pharmacologic class
C. Equivalent rate and extent of absorption
D. Similar price
- ANSWER: C
❤️ SECTION 2: Cardiovascular & Renal Pharmacology
