ALL THE COMSAE Questions and
Answers Graded A+
Giardia lamblia - Correct answer-tinidazole or nitazoxanide (alt: metronidazole)
Entamoeba histolytica - Correct answer-metronidazole or tinidazole, then
paromomycin or iodoquinol
Ascaris lumbricoides - Correct answer-albendazole or mebendazole
Necator americanus - Correct answer-albendazole (alt: mebendazole)
Trichinella spiralis - Correct answer-albendazole + prednisone
Enterobius vermicularis - Correct answer-mebendazole
Shistosoma spp. - Correct answer-praziquantel
Diphyllobothrium latum - Correct answer-praziquantel (alt: niclosamide)
Yersinia Pestis - Correct answer-Streptomycin (alt: gentamicin
Adenovirus (severe infection) - Correct answer-cidofovir + probenecid
Influenza A (seasonal), Influenza B, adn avian flu (H5N1) - Correct answer-
zanamivir or oseltamivir
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,Measles - Correct answer--Children: vitamin A
-Adults: ribavirin
Smallpox - Correct answer-smallpox vaccine within 4 days of exposure + cidofovir
+ probenecid
Osteomyelitis (<4 months old) - Correct answer-nafcillin or oxacillin + ceftazidime
or cefepime
Osteomyelitis (4 months - adult) - Correct answer-nafcillin or oxacillin
Herpes Encephalitis - Correct answer--acyclovir
-if HSV (+): acyclovir
-If not HSV (+): DOC for specific etiologic agent
Encephalitis due to Rickettsia, Anaplasma, Ehrlichia, Bartonella, or Mycoplasma -
Correct answer-Doxycycline
Encephalitis due to Borrelia burgdorferi - Correct answer-Ceftriaxone
Meningitis in neonate, child, or adult - Correct answer-ampicillin + cefotaxime +
gentamicin + ceftriaxone or cefotaxime + dexamethasone + vacomycin
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, Meningitis in alcoholics, people >50, people with severe comorbid diseases, or
anyone who is immunocompromised - Correct answer-ceftriaxone or cefotaxime +
dexamethasone + vacomycin + ampcillin
Meningitis prophylaxis if hemophilus influenzae - Correct answer-rifampin
Meningitis prophylaxis if neisseria meningitidis - Correct answer-rifampin or
ceftriaxone or ciprofloxacin
Otitis externa - Correct answer-acetic acid + propylene glycol + hydrocortisone
drops
or
Cirpofloxacin + hydrocortisone drops
Otitis media - Correct answer--amoxicillin if <2 y/o
-analgesics if >2 with no pain or fever
Viral conjunctivitis - Correct answer-nothing or chilled artificial tears
Bacterial conjunctivitis - Correct answer-fluoroquinolone drops
Neonatal conjunctivitis with onset within 1st day of life - Correct answer-nothing
Neonatal conjunctivitis with onset within 2-4 days of life - Correct answer-IV
ceftriaxone + PO erythromycin
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Answers Graded A+
Giardia lamblia - Correct answer-tinidazole or nitazoxanide (alt: metronidazole)
Entamoeba histolytica - Correct answer-metronidazole or tinidazole, then
paromomycin or iodoquinol
Ascaris lumbricoides - Correct answer-albendazole or mebendazole
Necator americanus - Correct answer-albendazole (alt: mebendazole)
Trichinella spiralis - Correct answer-albendazole + prednisone
Enterobius vermicularis - Correct answer-mebendazole
Shistosoma spp. - Correct answer-praziquantel
Diphyllobothrium latum - Correct answer-praziquantel (alt: niclosamide)
Yersinia Pestis - Correct answer-Streptomycin (alt: gentamicin
Adenovirus (severe infection) - Correct answer-cidofovir + probenecid
Influenza A (seasonal), Influenza B, adn avian flu (H5N1) - Correct answer-
zanamivir or oseltamivir
©COPYRIGHT 2025, ALL RIGHTS RESERVED 1
,Measles - Correct answer--Children: vitamin A
-Adults: ribavirin
Smallpox - Correct answer-smallpox vaccine within 4 days of exposure + cidofovir
+ probenecid
Osteomyelitis (<4 months old) - Correct answer-nafcillin or oxacillin + ceftazidime
or cefepime
Osteomyelitis (4 months - adult) - Correct answer-nafcillin or oxacillin
Herpes Encephalitis - Correct answer--acyclovir
-if HSV (+): acyclovir
-If not HSV (+): DOC for specific etiologic agent
Encephalitis due to Rickettsia, Anaplasma, Ehrlichia, Bartonella, or Mycoplasma -
Correct answer-Doxycycline
Encephalitis due to Borrelia burgdorferi - Correct answer-Ceftriaxone
Meningitis in neonate, child, or adult - Correct answer-ampicillin + cefotaxime +
gentamicin + ceftriaxone or cefotaxime + dexamethasone + vacomycin
©COPYRIGHT 2025, ALL RIGHTS RESERVED 2
, Meningitis in alcoholics, people >50, people with severe comorbid diseases, or
anyone who is immunocompromised - Correct answer-ceftriaxone or cefotaxime +
dexamethasone + vacomycin + ampcillin
Meningitis prophylaxis if hemophilus influenzae - Correct answer-rifampin
Meningitis prophylaxis if neisseria meningitidis - Correct answer-rifampin or
ceftriaxone or ciprofloxacin
Otitis externa - Correct answer-acetic acid + propylene glycol + hydrocortisone
drops
or
Cirpofloxacin + hydrocortisone drops
Otitis media - Correct answer--amoxicillin if <2 y/o
-analgesics if >2 with no pain or fever
Viral conjunctivitis - Correct answer-nothing or chilled artificial tears
Bacterial conjunctivitis - Correct answer-fluoroquinolone drops
Neonatal conjunctivitis with onset within 1st day of life - Correct answer-nothing
Neonatal conjunctivitis with onset within 2-4 days of life - Correct answer-IV
ceftriaxone + PO erythromycin
©COPYRIGHT 2025, ALL RIGHTS RESERVED 3
