FUNDAMENTALS OF CHEMOTHERAPY IMMUNOTHERAPY
ADMINISTRATION EXAM QUESTIONS AND CORRECT DETAILED ANSWERS
TOP RATED VERSION FOR ALREADY A+ GRADED WITH EXPERT FEEDBACK
| NEW AND REVISEDFUNDAMENTALS OF CHEMOTHERAPY
IMMUNOTHERAPY ADMINISTRATION EXAM QUE 2025
Terms in this set (89)
-cancer that begins in bone marrow or immune system cells.
Hematologic cancer (blood cancer)
-Ex: leukemia, lymphoma, multiple myeloma
cancer starts in blood-forming tissues like bone marrow
Leukemia
-causes lots of abnormal blood cells to be produced and enter bloodstream
-cancer that begins in immune system (WBC=lymphocytes)
-hodgkin and non-hodgkins
Lymphoma -B lymphocytes (B cells) - make antibodies (bacteria and viruses,
most common lymphoma
-T lymphocytes (T cells) - boost/slow immune, destroy germs and
abnormal cells
Reed-Sternberg cell (cancer cells in classic)
Hodgkin lymphoma
-typically starts in B cells
-large, diverse group of cancers in immune system cells
Non-Hodgkin's Lymphoma
-indolent (slow growing) or aggressive (fast)
Myeloma Cancer in plasma cells (WBC that produce antibodies)
All antineoplastic agents used to treat cancer, given through oral and
Chemotherapy
parenteral
routes or other routes as specified in the standard, not including hormonal
therapies.
Written and signed by licensed independent practitioners
Who can order chemotherapy?
(MD/DO, PA, Oncology NP)
Can you use verbal orders for NO! Only when holding/stopping admin.
chemotherapy?
Who can mix Chemotherapy? Pharmacist, Pharmacy tech, MD/DO, qualified RN
Registered Nurses with specialized education, prep and training.
Who can administer chemotherapy?
See specific state laws and statutes
How often is chemo competency Annual continuing ed and competency assessment is recommended
reassessed>
-confirm plan with patient
-two practitioners verify: drug name, dose, volume, rate, route,
What is the dose verification
expiration date, appearance
process?
-document verification in chart
, -Gloves: two pairs, HD tested
What PPE is required for IV -Gown: disposable, back closed, long sleeved
Chemotherapy? -Respirator: NIOSH approved
-Eye & Face: face shield/mask
Neoadjuvant therapy (tumor Chemo BEFORE primary treatment (common in breast and colon)
burden)
Adjuvant therapy Chemo AFTER primary treatment (common in solid tumor)
Bone Marrow soft, sponge-like tissue in center of most bones, produce WBC, RBC, and
platelets.
Myelosuppression bone marrow activity is decreased, causing less RBC, WBC and Platelets.
Myeloablation severe myelosuppression
Induction phase initial phase, typically in hospital, intended myelosuppression
Consolidation phase after successful induction, kills cancer cells left in body (ex
(intensification/postremission radiation, stem cell transplant)
therapy)
Synergy when one chemo drug helps another work better at the same time
Complete response no identifiable cancer present for at least one month or longer
Partial response Measurable tumor reduced by 50% for at least one month with no new
tumors
Stable disease Tumor size reduced by less than 50% or less than 25% increase in growth
Progressive disease tumor growth more than 25% or new cancer
-G1 phase
-S phase
What are the phases of the cell
-G2 phase
cycle?
-M phase
What happens in G1 phase? The cell increases in size and prepares to replicate its DNA.
What do chemo drugs do to Prevent cell from making DNA and/or RNA (replicating)
target S phase? (ex: antifolates (methotrexate), antipyrimidines (5-fu), antipurines
(hydroxyurea))
Cells prepare to divide, chemo drugs stop development of
What do chemo drugs do to
elements needed for cell division
target G2 phase?
(ex: topoisomerase I and II inhibitors, bleomycin)
Cells divide, drugs prevent cell division, including metaphase arrest or
What do chemo drugs do to
microtubular disorganization
target M phase?
(ex: plant alkaloids and taxanes)
Active throughout the cell cycle:
-alkylating agents
What are some examples of cell
-anthracycline antibiotics
cycle non- specific drugs? -nitrosureas
-miscellaneous
ADMINISTRATION EXAM QUESTIONS AND CORRECT DETAILED ANSWERS
TOP RATED VERSION FOR ALREADY A+ GRADED WITH EXPERT FEEDBACK
| NEW AND REVISEDFUNDAMENTALS OF CHEMOTHERAPY
IMMUNOTHERAPY ADMINISTRATION EXAM QUE 2025
Terms in this set (89)
-cancer that begins in bone marrow or immune system cells.
Hematologic cancer (blood cancer)
-Ex: leukemia, lymphoma, multiple myeloma
cancer starts in blood-forming tissues like bone marrow
Leukemia
-causes lots of abnormal blood cells to be produced and enter bloodstream
-cancer that begins in immune system (WBC=lymphocytes)
-hodgkin and non-hodgkins
Lymphoma -B lymphocytes (B cells) - make antibodies (bacteria and viruses,
most common lymphoma
-T lymphocytes (T cells) - boost/slow immune, destroy germs and
abnormal cells
Reed-Sternberg cell (cancer cells in classic)
Hodgkin lymphoma
-typically starts in B cells
-large, diverse group of cancers in immune system cells
Non-Hodgkin's Lymphoma
-indolent (slow growing) or aggressive (fast)
Myeloma Cancer in plasma cells (WBC that produce antibodies)
All antineoplastic agents used to treat cancer, given through oral and
Chemotherapy
parenteral
routes or other routes as specified in the standard, not including hormonal
therapies.
Written and signed by licensed independent practitioners
Who can order chemotherapy?
(MD/DO, PA, Oncology NP)
Can you use verbal orders for NO! Only when holding/stopping admin.
chemotherapy?
Who can mix Chemotherapy? Pharmacist, Pharmacy tech, MD/DO, qualified RN
Registered Nurses with specialized education, prep and training.
Who can administer chemotherapy?
See specific state laws and statutes
How often is chemo competency Annual continuing ed and competency assessment is recommended
reassessed>
-confirm plan with patient
-two practitioners verify: drug name, dose, volume, rate, route,
What is the dose verification
expiration date, appearance
process?
-document verification in chart
, -Gloves: two pairs, HD tested
What PPE is required for IV -Gown: disposable, back closed, long sleeved
Chemotherapy? -Respirator: NIOSH approved
-Eye & Face: face shield/mask
Neoadjuvant therapy (tumor Chemo BEFORE primary treatment (common in breast and colon)
burden)
Adjuvant therapy Chemo AFTER primary treatment (common in solid tumor)
Bone Marrow soft, sponge-like tissue in center of most bones, produce WBC, RBC, and
platelets.
Myelosuppression bone marrow activity is decreased, causing less RBC, WBC and Platelets.
Myeloablation severe myelosuppression
Induction phase initial phase, typically in hospital, intended myelosuppression
Consolidation phase after successful induction, kills cancer cells left in body (ex
(intensification/postremission radiation, stem cell transplant)
therapy)
Synergy when one chemo drug helps another work better at the same time
Complete response no identifiable cancer present for at least one month or longer
Partial response Measurable tumor reduced by 50% for at least one month with no new
tumors
Stable disease Tumor size reduced by less than 50% or less than 25% increase in growth
Progressive disease tumor growth more than 25% or new cancer
-G1 phase
-S phase
What are the phases of the cell
-G2 phase
cycle?
-M phase
What happens in G1 phase? The cell increases in size and prepares to replicate its DNA.
What do chemo drugs do to Prevent cell from making DNA and/or RNA (replicating)
target S phase? (ex: antifolates (methotrexate), antipyrimidines (5-fu), antipurines
(hydroxyurea))
Cells prepare to divide, chemo drugs stop development of
What do chemo drugs do to
elements needed for cell division
target G2 phase?
(ex: topoisomerase I and II inhibitors, bleomycin)
Cells divide, drugs prevent cell division, including metaphase arrest or
What do chemo drugs do to
microtubular disorganization
target M phase?
(ex: plant alkaloids and taxanes)
Active throughout the cell cycle:
-alkylating agents
What are some examples of cell
-anthracycline antibiotics
cycle non- specific drugs? -nitrosureas
-miscellaneous
