NSG 6005 Week 2 Pharmacology
Questions and Answers Graded A+
The major reason for not crushing a sustained release capsule is that, if crushed,
the coated beads of the drugs could possibly result in:
o Disintegration
o Toxicity
o Malabsorption
o Deterioration - Correct answer-o Toxicity
Drugs that have a significant first pass effect:
o Must be given by enteral (oral) route only
o Bypass the hepatic circulation
o Are rapidly metabolized by the liver and may have little if any desired action
,o Are converted by the liver to more active in fat-soluble forms - Correct answer-o
Are rapidly metabolized by the liver and may have little if any desired action
When obtaining a drug history from Harold, he gives you a complete list of his
prescription medications. He denies taking any other drugs, but you find that he
occasionally takes aspirin for his arthritis flare-ups. This is an example of:
o His appropriately only telling you about his regularly prescribed medications
o His hiding information regarding his inappropriate use of aspirin from you
o His common misconception that intermittently taking OTC medications are not
an important part of his drug history
o A common misuse of OTC aspirin - Correct answer-o His common
misconception that intermittently taking OTC medications are not an important
part of his drug history
Drugs that use CYP3A4 isoenzymes for metabolism may:
o Induce the metabolism of another drug
o Inhibit the metabolism of another drug
,o Both A and B
o Neither A nor B - Correct answer-o Both A and B
A twenty four year old male received multiple fractures in a motor vehicle accident
that required significant amounts of opioid medication to treat his pain. He is at
risk for Type ____ ADR when he no longer requires the opioids.
oA
oC
oE
o G - Correct answer-o E
Infants and young children are at higher risk of ADRs due to:
o Immature renal function in schoolage children
o Lack of safety and efficacy studies in the pediatric population
o Children's skin being thicker than adults, requiring higher dosages of topical
medication
, o Infant boys having a higher proportion of muscle mass, leading to a higher
volume of distribution - Correct answer-o Lack of safety and efficacy studies in the
pediatric population
The type of ADR that is the result of an unwanted but otherwise normal
pharmacological action of a drug given in the usual therapeutic dose is:
o Type A
o Type B
o Type C
o Type D - Correct answer-o Type A
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old
because:
o Drugs given in liquid form are less irritating to the stomach.
o A six-year-old may have problems swallowing a pill.
o Liquid forms of medication eliminate the concern for first-pass effect.
Questions and Answers Graded A+
The major reason for not crushing a sustained release capsule is that, if crushed,
the coated beads of the drugs could possibly result in:
o Disintegration
o Toxicity
o Malabsorption
o Deterioration - Correct answer-o Toxicity
Drugs that have a significant first pass effect:
o Must be given by enteral (oral) route only
o Bypass the hepatic circulation
o Are rapidly metabolized by the liver and may have little if any desired action
,o Are converted by the liver to more active in fat-soluble forms - Correct answer-o
Are rapidly metabolized by the liver and may have little if any desired action
When obtaining a drug history from Harold, he gives you a complete list of his
prescription medications. He denies taking any other drugs, but you find that he
occasionally takes aspirin for his arthritis flare-ups. This is an example of:
o His appropriately only telling you about his regularly prescribed medications
o His hiding information regarding his inappropriate use of aspirin from you
o His common misconception that intermittently taking OTC medications are not
an important part of his drug history
o A common misuse of OTC aspirin - Correct answer-o His common
misconception that intermittently taking OTC medications are not an important
part of his drug history
Drugs that use CYP3A4 isoenzymes for metabolism may:
o Induce the metabolism of another drug
o Inhibit the metabolism of another drug
,o Both A and B
o Neither A nor B - Correct answer-o Both A and B
A twenty four year old male received multiple fractures in a motor vehicle accident
that required significant amounts of opioid medication to treat his pain. He is at
risk for Type ____ ADR when he no longer requires the opioids.
oA
oC
oE
o G - Correct answer-o E
Infants and young children are at higher risk of ADRs due to:
o Immature renal function in schoolage children
o Lack of safety and efficacy studies in the pediatric population
o Children's skin being thicker than adults, requiring higher dosages of topical
medication
, o Infant boys having a higher proportion of muscle mass, leading to a higher
volume of distribution - Correct answer-o Lack of safety and efficacy studies in the
pediatric population
The type of ADR that is the result of an unwanted but otherwise normal
pharmacological action of a drug given in the usual therapeutic dose is:
o Type A
o Type B
o Type C
o Type D - Correct answer-o Type A
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old
because:
o Drugs given in liquid form are less irritating to the stomach.
o A six-year-old may have problems swallowing a pill.
o Liquid forms of medication eliminate the concern for first-pass effect.
