Genetics and Genomics in Nursing and Health Care
Theresa A. Beery, M. Linda Workman, and Julia A. Eggert
2nd Edition
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Table of Contents
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Chapter 01 DNA Structure and Function
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,Chapter 02 Protein Synthesis
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Chapter 03 Genetic Influence on Cell Division, Differentiation, and Gametogenesis
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Chapter 04 Patterns of Inheritance
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Chapterww 05 Epigenetic Influences on Gene Expression
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Chapterww 06 Autosomal Inheritance and Disorders
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Chapterww 07 Sex Chromosome and Mitochondrial Inheritance and Disorders
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Chapterww 08 Family History and Pedigree Construction
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Chapterww 09 Congenital Anomalies, Basic Dysmorphology, and Genetic Assessment
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Chapterww 10 Enzyme and Collagen Disorders
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Chapterww 11 Common Childhood-Onset Genetic Disorders
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Chapterww 12 Common Adult-Onset Disorders
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Chapterww 13 Cardiovascular Disorders
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Chapterww 14 The Genetics of Cancer
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Chapterww 15 Genetic Contributions to Psychiatric and Behavioral Disorders
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Chapterww 16 Genetic and Genomic Testing
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Chapterww 17 Assessing Genomic Variation in Drug Response
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Chapterww 18 Health Professionals and Genomic Care
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Chapterww 19 Financial, Ethical, Legal, and Social Considerations
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Chapterww 20 Genetic and Genomic Variation
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Genetics and Genomics in Nursing and Health Care, 2nd Edition (Beery, 2019)
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Chapter 1: DNA Structure and Function
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MULTIPLE CHOICE ww
1. In which body or cell area are most genes in humans located?
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a. Nucleus
b. Mitochondrion
c. Cytoplasm
d. Plasma membrane ww
ANS: A www w
Most genes are part of the DNA located in the nucleus of body cells. Only a few genes ar
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e located in a cell’s mitochondrion or mitochondria. There are no genes or DNA in either t
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he cytoplasm or the plasma membranes of any cell.
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2. Which condition or statement exemplifies the concept of genomics rather than genetics?
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a. The gene for insulin is located on chromosome 11 in all people.
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b. Expression of any single gene is dependent on inheriting two alleles.
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c. Sex-linked recessive disorders affect males more often than females.
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d. One allele for each gene is inherited from the mother, and one is inherited from
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the father. w ww
ANS: A www w
Genetics is the study of the general mechanisms of heredity and the variation of inherite
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d traits. Genomics is the study of the function of all the nucleotide sequences present wi
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thin the entire genome of a s p e c i e s , Wi nWcW
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n DNA coding regions and DNA n
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oncoding
regions. Selections B, C, and D all refer to mechanisms of heredity. Only selection A refers
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to the function of a specific nucleotide sequence.
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3. What is the purpose of phosphorous in a DNA strand?
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a. Linking the nucleotides into a strand ww ww ww ww ww
b. Holding complementary strands together ww ww ww
c. Ensuring that a purine is always paired with a pyrimidine
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d. Preventing the separation of double-stranded DNA into single-stranded DNA
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ANS: A www w
Each nucleoside becomes a complete nucleotide when a phosphate group is attached. Th
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e phosphates have multiple binding sites, and each one can link to two nucleotides. The
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se linkages allow the nucleotides to be connected when placed into the DNA strand. Th
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e nucleotides within each strand are held in position by the linked phosphate groups, wh
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ich act like the string holding a strand of beads together, forming a necklace.
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4. What is the term used to define alternative forms of a gene that may result in diffe
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rent expression of the trait coded for by that gene?
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a. Alleles
b. Bases
c. Centromeres
d. Diploids
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