UPDATE 2026/2027) || BRADLEY UNIVERSITY || VERIFIED
ANSWERS || A+ PERFORMANCE BLUEPRINT || HIGH-YIELD,
CLINICALLY FOCUSED REVIEW
Which of the types of chemical bonding between drugs and their receptors is the
least common? - CORRECT ANSWER -Covalent
Which type of drug classification is most important to the practitioner? -
CORRECT ANSWER -Therapeutic
Mechanism of Action - CORRECT ANSWER -The manner in which
molecular targets are affected by the drug
What is bioavailability? - CORRECT ANSWER -The fraction of
unchanged drug that reaches the systemic circulation following administration
by any route
Absorption is defined as: - CORRECT ANSWER -The transfer of a drug
from its site of administration to the blood
How can Competitive antagonism be overcome? - CORRECT ANSWER -
by adding more agonist
How is children's dosing most often calculated? - CORRECT ANSWER -
MG/KG
Adverse Drug Reaction (ADR) can lead the patient to - CORRECT
ANSWER -stop taking the drug
Half-life is defined as - CORRECT ANSWER -The time required for the
plasma concentration of a drug to be reduced by 50 percent
When one drug is more efficacious than another, it has... - CORRECT
ANSWER -A greater ability to initiate a response
A patient complains of pain from a migraine. How would the practitioner
classify this type of pain? - CORRECT ANSWER -Central Neuropathic
Pain
,What stage of nociception is occurring when neurotransmitters in the dorsal
horn directly or indirectly depolarize the second-order neurons? - CORRECT
ANSWER -Trasmission
What are the four processes of Nociception - CORRECT ANSWER -
transduction, transmission, modulation, and perception
A practitioner conducting a pain assessment asks the patient, "Is the pain
consistent or intermittent?" What character of pain is the practitioner assessing?
- CORRECT ANSWER -Temporal pattern
What is the maximum dose of acetaminophen in 24 hours? - CORRECT
ANSWER -4 grams
Etodolac is in the same drug class as ibuprofen. What is its mechanism of
action? - CORRECT ANSWER -It inhibits the cyclooxygenase enzyme.
What kind of drug is Naloxone (Narcan) - CORRECT ANSWER -opioid
antagonist
Acetaminophen and alcohol have a complex relationship in the liver. Why? (3
reasons) - CORRECT ANSWER -1. They are both metabolized by the same
liver enzyme.
2. Alcohol inhibits the enzyme that metabolizes acetaminophen.
3. The enzyme that metabolizes acetaminophen is induced by alcohol.
What is a contraindication of ibuprofen? - CORRECT ANSWER -Ulcers
, An adverse effect of opiates in elders is... - CORRECT ANSWER -Bone
fractures
Aspirin is different from the other NSAIDs because... - CORRECT
ANSWER -It binds irreversibly to the COX enzyme
One of the properties that insulins are differentiated by is... - CORRECT
ANSWER -Duration of action
Which form of insulin is the most bioavailable? - CORRECT ANSWER -
Humalog
What is the mechanism of action of sitagliptin (Januvia)? - CORRECT
ANSWER -Slows the inactivation of incretin hormones by inhibiting
dipeptidyl peptidase 4
How does canagliflozin (Invokana) control blood glucose levels? -
CORRECT ANSWER -By reducing glucose reabsorption in the kidneys
What is the mechanism of action of Lantus? - CORRECT ANSWER -
Insulin precipitates into crystals and is slowly absorbed over 24 hours
The most common complication of insulin therapy is... - CORRECT
ANSWER -Hypoglycemia
What is the mechanism of action of the sulfonylureas? - CORRECT
ANSWER -Increases insulin secretion