ASCP CERTIFICATION QUESTIONS WITH CORRECT ANSWERS .

ASCP CERTIFICATION QUESTIONS
WITH CORRECT ANSWERS 2025-
2026
loss of DNA --> nuclear pallor = CORRECT ANSWER karyolysis


nuclear shrinkage and increased basophilia = CORRECT ANSWER pyknosis


fragmented, pyknotic nucleus = CORRECT ANSWER karyorrhexis


architecture is preserved in whatsnecrosis? CORRECT ANSWER coagulative

bacteria/fungus/inflammation/enzymes are part of whatsnecrosis? -sCORRECT ANSWERs-liquifactive



WBC recruitment steps - CORRECT ANSWERs-margination/rolling --> adhesion --> transmigration --
> migration



WBC rolling via CORRECT ANSWER selectins


WBC adhesion via CORRECT ANSWER integrins


Virchow's triad of thrombosis CORRECT ANSWER
endothelial injury + stasis/turbulent blood flow + hypercoagulability



mostsabundant collagen CORRECT ANSWER type I


collagen in scar tissue, tendons, ligaments CORRECT ANSWER type I


collagen in cartilage CORRECT ANSWER type II

,reticular collagen type -sCORRECT ANSWERs-type III

,BM collagen type CORRECT ANSWER type IV

what does vWF do? -sCORRECT ANSWER -helps platelets adhere to endothelium



FBN1 mutation = what disorder CORRECT ANSWER Marfan syndrome


fibrillin mutation = what disorder CORRECT ANSWER Marfan syndrome


mutated collagen = what disorder CORRECT ANSWER Ehlers-Danlos


musty urine odor = what disorder CORRECT ANSWER PKU


mutated beta-hexosaminidase A = what disorder CORRECT ANSWER Tay Sachs


increased gangliosides = what disorder CORRECT ANSWER Tay Sachs


mutated sphingomyelinase/increased sphingomyelin = what disorder CORRECT ANSWER
Neimann Pick



mutated glucocerebrosidase/increased glucocerebroside = what disorder CORRECT ANSWER
Gaucher



trisomy 13 aka -sCORRECT ANSWER -Patau



Patau = CORRECT ANSWER trisomy 13

trisomy 18 aka -sCORRECT ANSWER -Edwards'

, Edwards' = CORRECT ANSWER trisomy 18