Page 1 of 94
NGR 5172 - Advanced Pharmacology Final EXAM
QUESTIONS AND CORRECT DETAILED SOLUTIONS
LATEST UPDATED VERSION JUST RELEASED
Which of the following is a characteristic of very low-density lipoprotein (VLDL)?
Water-soluble transport for synthesized lipids
________ are the major dietary lipid.
Triacylglycerol
Fat-soluble vitamins include all of the following except:
C.
Which of the following is a water-soluble transport for ingested lipids?
Chylomicron
A major function of bile salts is:
Emulsification of dietary fat.
The free cholesterol pool of the liver is supplied primarily by which of the following
mechanisms?
Intracellular synthesis via the HMG-CoA reductase pathway
, Page 2 of 94
Cholesterol is obtained either by diet or is synthesized by a pathway that occurs in most body
cells but to a greater extent in the cells of which two organs?
Liver and intestines
During the fed state, free fatty acids are converted to triacylglycerol and stored in:
Adipose tissue.
Which of the following agents is beta 1 selective?
Atenolol
Which of the following statements about beta-adrenergic blockers is correct?
Some beta-adrenergic blockers are cardioselective, blocking only beta 1 receptors; others are
not and also block beta 2 receptors in smooth muscle.
The beta-adrenergic agonist nebivolol:
Is highly cardioselective.
During diuretic therapy, levels of which electrolyte should be monitored?
Potassium
Thiazide diuretics and loop diuretics have different primary indications because of which
important difference between them?
, Page 3 of 94
Thiazide diuretics require luminal perfusion to reach their active site.
During diuretic therapy, which of the following should be monitored?
Renal function
Which of the following is a mechanism of action of beta-adrenergic blockers?
Preventing sympathetic stimulation of the heart
Which type of diuretic is available only for oral use?
Potassium-sparing diuretics
Which of the following best characterizes the mechanism of action of diuretics?
Diuretics inhibit the transport of ions across the tubular membrane.
Which of the following statements about angiotensin II receptor blockers is correct?
Renal alterations are less common than with ACE inhibitors.
The baseline laboratory evaluation of patients taking ACE inhibitors should include:
Urine protein.
When prescribing angiotensin-converting enzyme (ACE) inhibitors, the advanced practice
nurse may anticipate all of the following:
Hypokalemia.
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The only absolute contraindication to ACE inhibitor use is:
Bilateral renal artery stenosis.
The HCN channel blocker ivabradine (Corlanor) is contraindicated for CHF patients with:
Atrial fibrillation.
Angiotensin II stimulates the release of which hormone that causes sodium and water
retention in the kidneys?
Aldosterone
The most common adverse effects of calcium channel blockers are:
Related to vasodilation.
When considering the use of valsartan/sacubitril (Ernesto) for congestive heart failure, the NP
considers all of the following except:
There are few significant drug-drug interactions.
Which of the following agents attenuates the hypotensive effects of ACE inhibitors?
Nonsteroidal anti-inflammatory agents (NSAIDs)
The renin inhibitor, aliskiren, can significantly reduce the activity of:
Loop diuretics.
NGR 5172 - Advanced Pharmacology Final EXAM
QUESTIONS AND CORRECT DETAILED SOLUTIONS
LATEST UPDATED VERSION JUST RELEASED
Which of the following is a characteristic of very low-density lipoprotein (VLDL)?
Water-soluble transport for synthesized lipids
________ are the major dietary lipid.
Triacylglycerol
Fat-soluble vitamins include all of the following except:
C.
Which of the following is a water-soluble transport for ingested lipids?
Chylomicron
A major function of bile salts is:
Emulsification of dietary fat.
The free cholesterol pool of the liver is supplied primarily by which of the following
mechanisms?
Intracellular synthesis via the HMG-CoA reductase pathway
, Page 2 of 94
Cholesterol is obtained either by diet or is synthesized by a pathway that occurs in most body
cells but to a greater extent in the cells of which two organs?
Liver and intestines
During the fed state, free fatty acids are converted to triacylglycerol and stored in:
Adipose tissue.
Which of the following agents is beta 1 selective?
Atenolol
Which of the following statements about beta-adrenergic blockers is correct?
Some beta-adrenergic blockers are cardioselective, blocking only beta 1 receptors; others are
not and also block beta 2 receptors in smooth muscle.
The beta-adrenergic agonist nebivolol:
Is highly cardioselective.
During diuretic therapy, levels of which electrolyte should be monitored?
Potassium
Thiazide diuretics and loop diuretics have different primary indications because of which
important difference between them?
, Page 3 of 94
Thiazide diuretics require luminal perfusion to reach their active site.
During diuretic therapy, which of the following should be monitored?
Renal function
Which of the following is a mechanism of action of beta-adrenergic blockers?
Preventing sympathetic stimulation of the heart
Which type of diuretic is available only for oral use?
Potassium-sparing diuretics
Which of the following best characterizes the mechanism of action of diuretics?
Diuretics inhibit the transport of ions across the tubular membrane.
Which of the following statements about angiotensin II receptor blockers is correct?
Renal alterations are less common than with ACE inhibitors.
The baseline laboratory evaluation of patients taking ACE inhibitors should include:
Urine protein.
When prescribing angiotensin-converting enzyme (ACE) inhibitors, the advanced practice
nurse may anticipate all of the following:
Hypokalemia.
, Page 4 of 94
The only absolute contraindication to ACE inhibitor use is:
Bilateral renal artery stenosis.
The HCN channel blocker ivabradine (Corlanor) is contraindicated for CHF patients with:
Atrial fibrillation.
Angiotensin II stimulates the release of which hormone that causes sodium and water
retention in the kidneys?
Aldosterone
The most common adverse effects of calcium channel blockers are:
Related to vasodilation.
When considering the use of valsartan/sacubitril (Ernesto) for congestive heart failure, the NP
considers all of the following except:
There are few significant drug-drug interactions.
Which of the following agents attenuates the hypotensive effects of ACE inhibitors?
Nonsteroidal anti-inflammatory agents (NSAIDs)
The renin inhibitor, aliskiren, can significantly reduce the activity of:
Loop diuretics.
