2025 OCR GCSE Combined Science B (Twenty First Century Science)
J260/05 Biology (Higher Tier)
Complete Question paper with Marking Scheme Combined
Tuesday 13 May 2025 – Afternoon
GCSE (9–1) Combined Science B
(Twenty First Century Science)
J260/05 Biology (Higher Tier)
Time allowed: 1 hour 45 minutes
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra
space use the lined pages at the end of this booklet. The question numbers
must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working.
Marks might be given for using a correct method, even if your answer is
wrong.
INFORMATION
• The total mark for this paper is 95.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an
asterisk (*).
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/8690/2] DC (SL/CT)
,352896/5
OCR is an exempt
Charity Turn over
, 2
BLANK PAGE
DO NOT WRITE ON THIS PAGE
© OCR
2025
, 3
1 There are two types of cell division, meiosis and mitosis.
(a) Complete the table to show which type of cell division is described by each
statement. Tick (✓) one box in each row.
Statement Both types Meiosis only Mitosis only Neither
of cell type of cell
division division
It involves two divisions to
produce four new cells.
It makes new cells for
growth and repair of tissues
in adults.
It produces cells with half the
number of chromosomes.
It produces gametes.
[4]
(b) Cancer is the result of changes in cells.
(i) In which part of a cell do these changes
occur? Tick (✓) one box.
Cell membrane
Cell wall
Cytoplasm
DNA
[1]
(ii) Describe how the changes lead to a single cell forming a tumour.
............................................................................................................................................
..............
............................................................................................................................................
..............
............................................................................................................................................
..............
.................................................................................................................................. [2]
© OCR Turn over
2025
J260/05 Biology (Higher Tier)
Complete Question paper with Marking Scheme Combined
Tuesday 13 May 2025 – Afternoon
GCSE (9–1) Combined Science B
(Twenty First Century Science)
J260/05 Biology (Higher Tier)
Time allowed: 1 hour 45 minutes
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra
space use the lined pages at the end of this booklet. The question numbers
must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working.
Marks might be given for using a correct method, even if your answer is
wrong.
INFORMATION
• The total mark for this paper is 95.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an
asterisk (*).
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/8690/2] DC (SL/CT)
,352896/5
OCR is an exempt
Charity Turn over
, 2
BLANK PAGE
DO NOT WRITE ON THIS PAGE
© OCR
2025
, 3
1 There are two types of cell division, meiosis and mitosis.
(a) Complete the table to show which type of cell division is described by each
statement. Tick (✓) one box in each row.
Statement Both types Meiosis only Mitosis only Neither
of cell type of cell
division division
It involves two divisions to
produce four new cells.
It makes new cells for
growth and repair of tissues
in adults.
It produces cells with half the
number of chromosomes.
It produces gametes.
[4]
(b) Cancer is the result of changes in cells.
(i) In which part of a cell do these changes
occur? Tick (✓) one box.
Cell membrane
Cell wall
Cytoplasm
DNA
[1]
(ii) Describe how the changes lead to a single cell forming a tumour.
............................................................................................................................................
..............
............................................................................................................................................
..............
............................................................................................................................................
..............
.................................................................................................................................. [2]
© OCR Turn over
2025
