FULL SOLUTION 2026 GUARANTEED TO
PASS.
⫸ plasma without clotting factors. Answer: serum
⫸ What is innate response. Answer: Rapid, non-specific, no memory,
usually resolves 95% of infections
⫸ When innate response fails,. Answer: adaptive response
⫸ what does adaptive response do?. Answer: activated 24 post
infection, slow to respond, requires activation/differentiation of
lymphocytes, specific response, memory
⫸ types of leukocytes. Answer: myeloid, lymphocyte, dendritic
⫸ role of neutrophils. Answer: phagocytose and kill bacteria
⫸ role of macrophage. Answer: phagocytose and kill bacteria, alert
immune system, tissue repair
⫸ role of dendritic cell. Answer: phagocytose and kill
bacteria/viruses, activate adaptive immune response
,⫸ most abundant cell type. Answer: neutrophil
⫸ types of lymphocytes. Answer: T cells, B cells, NK cells
⫸ types of t cells. Answer: cytotoxic t cells (CTL), t-helper cells, t-
regulatory cells
⫸ role of B cells. Answer: secrete antibodies
⫸ role of CTL. Answer: kill viral infected cells
⫸ T helper cells. Answer: provide cytokines and other signals to
Bcells, CTLs and macrophages
⫸ all cells derived from. Answer: hematopoietic stem cells (HSC)
⫸ HSCs are found where?. Answer: bone marrow, blood, umbilical
cord
⫸ Can you "run out" of HSC?. Answer: no, they are self renewing
⫸ How common are HSC. Answer: less than 1% of bone marrow
pop.
, ⫸ where do B cells develop. Answer: bone marrow
⫸ where do T cells develop. Answer: bone marrow then thymus
⫸ where do lymphocytes encounter and respond to antigens
(pathogens)?. Answer: in secondary (peripheral) lymphoid organs
⫸ secondary lymphoid organs. Answer: spleen and lymph nodes,
gut-associated lymphoid tissues (GALT)
⫸ what is in lymph fluid. Answer: white blood cells and plasma
⫸ PAMPS are molecular structures that. Answer: are not found in
multicellular hosts, present on numerous groups of pathogens,
essential for microbe, do not undergo frequent mutation
⫸ how do innate response cells distinguish self from non-self?.
Answer: neutrophils, macrophages, dedritic cells have Pattern
Recognition receptors (PRR) to bind PAMPS
⫸ What happens when pathogen binds to PRR. Answer: it is
engulfed by the cell
⫸ toll-like receptors bound to PAMP results in. Answer: release of
cytokine, up-regulation of MHC class II, and B7