Complete Questions and Guide Answers
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1. Aldosterone is released by the adrenal cortex upon stimulation by:
A. Renin
B. Angiotensinogen
C. Angiotenisinogen I
D. Angiotensinogen II
Answer: D. Angiotensinogen II
2. Clinical Assays for tumor markers are most important for:
A. screening for the presence of cancer
B. monitoring the course of known cancer
C. confirming the absence of disease
D. identifying patients at risk for cancer
Answer: B. Monitoring the course of known cancer
,3. Detection of which of the following substances is most useful to monitor the course
of a patient with testicular cancer?
A. alpha-fetoprotein
B. carcinoembryonic antigen
C. prolactin
D. testosterone
Answer: A. alpha-fetoprotein
4. Increased concentrations of alpha-fetoprotein (AFP) in adults are most char-
acteristically associated with:
A. hepatocellular carcinoma
B. alcoholic cirrhosis
C. chronic active hepatitis
D. multiple myeloma
Answer: A. hepatocellular carcinoma
5. Carcinoembryonic antigen (CEA) is most likely to be produced in a maignancy involving
the:
,A. Brain
B. Testes
C. Bone
D. Colon
Answer: D. Colon
6. Which of the following is useful in the detection an management of carcinoma of the
prostate?
A. total prostate-specific antigen
B. prostatic acid phosphatase
C. human chorionic gonadotropin
D. alpha-fetoprotein
Answer: A. total prostate-specific antigen
7. Which of the following statements most correctly describes the utility of
clinical laboratory assays for tumor markers?
A. tumor markers are useful to screen asymptomatic patients for tumors
B. tumor markers are highly specific
, C. tumor markers indicate the likelihood of an individual developing a tumor
D. tumors are useful in tracking the efficacy of treatment
Answer: D.tumorsareusefulintracking the eflcacy of treatment
8. Cancer antigen 125 (CA 125) is a tumor marker associated with:
A. breast carcinoma
B. colon cancer
C. lung cancer
D. ovarian and endometrial carcinoma
Answer: D. ovarian and endometrial carcinoma
9. In addition to carcinoma of the prostate, elevated prostate-specific antigen (PSA)
can occur due to:
A. aspirin therapy
B. exogenous steroid use
C. benign prostatic hyperplasia
D. statin therapy (cholesterol lowering drugs)
Answer: C. benign prostatic hyperplasia