FINAL EXAM NURSING 507: ADVANCED
PATHOPHYSIOLOGY, 2025/2026 WITH
CORRECT/ACCURATE ANSWERS
AT CHAMBERLAIN UNIVERSITY
Final Exam (100 Questions, Multiple Choice)
ADVANCED PATHOPHYSIOLOGY
,QUESTIONS 1–13
1. What is the most common disorder of thyroid function?
A. Hypothyroidism
B. Hyperthyroidism
C. Thyroid cancer
D. Subacute thyroiditis
Correct Answer: A
Rationale: Hypothyroidism is far more common than hyperthyroidism in the general
population.
2. What does the hypothalamus release to regulate thyroid function?
A. ACTH
B. TRH
C. TSH
D. CRH
Correct Answer: B
Rationale: TRH stimulates the anterior pituitary to release TSH.
3. When TRH is released, what happens next?
A. Thyroid releases cortisol
B. Pituitary releases TSH
C. Thyroid releases insulin
D. Pancreas releases glucagon
Correct Answer: B
Rationale: TRH causes pituitary secretion of TSH, the major regulator of thyroid hormone
synthesis.
4. TSH stimulates production of which hormones?
A. T3 and T4
B. Insulin and glucagon
C. Cortisol and aldosterone
D. PTH and calcitonin
, Correct Answer: A
Rationale: TSH activates the thyroid gland to synthesize T3 and T4.
5. If the thyroid gland is not producing enough thyroid hormone, TSH will:
A. Decrease
B. Increase
C. Remain unchanged
D. Stop completely
Correct Answer: B
Rationale: Low thyroid hormone reduces negative feedback → TSH increases.
6. If the thyroid gland is producing too much thyroid hormone, TSH will:
A. Increase
B. Stay the same
C. Decrease
D. Fluctuate randomly
Correct Answer: C
Rationale: High thyroid hormone increases negative feedback → TSH decreases.
7. Which thyroid hormone comes exclusively from the thyroid gland?
A. T3
B. T4
C. rT3
D. Calcitonin
Correct Answer: B
Rationale: T4 is produced only by the thyroid; most T3 is converted peripherally.
8. Graves’ disease is a type of:
A. Hypothyroidism
B. Euthyroid goiter
C. Hyperthyroidism
PATHOPHYSIOLOGY, 2025/2026 WITH
CORRECT/ACCURATE ANSWERS
AT CHAMBERLAIN UNIVERSITY
Final Exam (100 Questions, Multiple Choice)
ADVANCED PATHOPHYSIOLOGY
,QUESTIONS 1–13
1. What is the most common disorder of thyroid function?
A. Hypothyroidism
B. Hyperthyroidism
C. Thyroid cancer
D. Subacute thyroiditis
Correct Answer: A
Rationale: Hypothyroidism is far more common than hyperthyroidism in the general
population.
2. What does the hypothalamus release to regulate thyroid function?
A. ACTH
B. TRH
C. TSH
D. CRH
Correct Answer: B
Rationale: TRH stimulates the anterior pituitary to release TSH.
3. When TRH is released, what happens next?
A. Thyroid releases cortisol
B. Pituitary releases TSH
C. Thyroid releases insulin
D. Pancreas releases glucagon
Correct Answer: B
Rationale: TRH causes pituitary secretion of TSH, the major regulator of thyroid hormone
synthesis.
4. TSH stimulates production of which hormones?
A. T3 and T4
B. Insulin and glucagon
C. Cortisol and aldosterone
D. PTH and calcitonin
, Correct Answer: A
Rationale: TSH activates the thyroid gland to synthesize T3 and T4.
5. If the thyroid gland is not producing enough thyroid hormone, TSH will:
A. Decrease
B. Increase
C. Remain unchanged
D. Stop completely
Correct Answer: B
Rationale: Low thyroid hormone reduces negative feedback → TSH increases.
6. If the thyroid gland is producing too much thyroid hormone, TSH will:
A. Increase
B. Stay the same
C. Decrease
D. Fluctuate randomly
Correct Answer: C
Rationale: High thyroid hormone increases negative feedback → TSH decreases.
7. Which thyroid hormone comes exclusively from the thyroid gland?
A. T3
B. T4
C. rT3
D. Calcitonin
Correct Answer: B
Rationale: T4 is produced only by the thyroid; most T3 is converted peripherally.
8. Graves’ disease is a type of:
A. Hypothyroidism
B. Euthyroid goiter
C. Hyperthyroidism
