How does histone acetylation affect chromatin structure?
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Neutralizes positive histone charges and binds to DNA more loosely
What are four things that influence the stability of eukaryotic mRNAs?
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(1) the 5′ cap
(2) the coding sequence
(3) the 3′ UTR
(4) the poly(A) tail
, How will the result of strand slippage on the newly synthesized strand differ from the
result of strand slippage on the template strand?
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Slippage on the newly synthesized strand will result in an insertion,
whereas slippage on the template strand will result in a deletion.
What effect does histone acetylation have on transcription?
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Measurably increase expression
You are scientist that studies the epigenetic effects of maternal behavior in rats. Which
of the following experimental manipulations would likely lead to a more normal stress
behavior in young rats?
a. Injection of glucocorticoid agonists into young rat brains
b. Injection of histone deacetylase inhibitors into young rat brains
c. Injection of DNA demethylase inhibitors into young rat brains
d. Feeding glucocorticoid inhibitors during early postnatal development
e. Each of these experimental treatments would likely lead to abnormal stress
responses.
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a. Injection of glucocorticoid agonists into young rat brains
Give this one a try later!
Neutralizes positive histone charges and binds to DNA more loosely
What are four things that influence the stability of eukaryotic mRNAs?
Give this one a try later!
(1) the 5′ cap
(2) the coding sequence
(3) the 3′ UTR
(4) the poly(A) tail
, How will the result of strand slippage on the newly synthesized strand differ from the
result of strand slippage on the template strand?
Give this one a try later!
Slippage on the newly synthesized strand will result in an insertion,
whereas slippage on the template strand will result in a deletion.
What effect does histone acetylation have on transcription?
Give this one a try later!
Measurably increase expression
You are scientist that studies the epigenetic effects of maternal behavior in rats. Which
of the following experimental manipulations would likely lead to a more normal stress
behavior in young rats?
a. Injection of glucocorticoid agonists into young rat brains
b. Injection of histone deacetylase inhibitors into young rat brains
c. Injection of DNA demethylase inhibitors into young rat brains
d. Feeding glucocorticoid inhibitors during early postnatal development
e. Each of these experimental treatments would likely lead to abnormal stress
responses.
Give this one a try later!
a. Injection of glucocorticoid agonists into young rat brains
