HL HL HL HL HL HL HL
CE
,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTI
HL HL HL HL HL HL HL
CE
,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTI
HL HL HL HL HL HL HL
CE
, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTI
HL HL HL HL HL HL HL
CE
Chapter 1, The Foundation of Pharmacology: Quality and Safety
HL HL HL HL HL HL HL HL
1. A woman diagnosed with obsessive–
HL HL HL HL
compulsive disorder has been prescribed oral paroxetine hydrochloride. What
HL HL HL HL HL HL HL HL HL
is the expected effect for this prescription?
HL HL HL HL HL HL
A. Curative effect on symptoms HL HL HL
B. Systemic effect on symptoms HL HL HL
C. Local effect on symptoms HL HL HL
D. Parenteral effect on symptoms HL HL HL
ANS: B H L
Rationale: Drugs that produce systemic effects are taken into the body, circulated thro
HL HL HL HL HL HL HL HL HL HL HL HL
ugh the bloodstream to their sites of action in various body tissues, and eventually eli
HL HL HL HL HL HL HL HL HL HL HL HL HL HL
minated from the body. Curative agents are given to cure a disease process. In this c
HL HL HL HL HL HL HL HL HL HL HL HL HL HL HL
ase, paroxetine hydrochloride will control the symptoms but not cure the disorder. Dru
HL HL HL HL HL HL HL HL HL HL HL HL
gs with local effects, such as sunscreen and local anesthetics, act mainly at the site of
HL HL HL HL HL HL HL HL HL HL HL HL HL HL HL
application. Paroxetine hydrochloride is not administered parenterally. Parenteral agent
HL HL HL HL HL HL HL HL HL
s are administered subcutaneously, intramuscularly, or intravenously.
HL HL HL HL HL HL
PTS: 1 REF: p. 3, Introduction OBJ: 1 HL HL
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Thera
HL HL HL HL HL HL HL HL
pies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
HL HL HL HL HL HL HL HL HL
KEY: Integrated Process: Nursing Process
H L HL HL HL
BLM: Cognitive Level: Understand
H L NOT: Multiple Choice HL HL H L HL
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
HL HL HL HL HL HL HL HL HL HL HL HL
substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TW
HL
.hCaOt Mi s another name for this type of medi
HL HL HL HL HL HL HL HL HL HL HL
cation?
A. Synthetic drug HL
B. Semisynthetic drug HL
C. Biotechnology drug HL
D. Prototype drug HL
ANS: B H L
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substanc
HL HL HL HL HL HL HL HL HL
es that have been chemically modified. Synthetic drugs are more standardized in their c
HL HL HL HL HL HL HL HL HL HL HL HL HL
hemical characteristics, more consistent in their effects, and less likely to produce alle
HL HL HL HL HL HL HL HL HL HL HL HL
rgic reactions. Biotechnology drugs involve manipulating DNA and RNA and recombi
HL HL HL HL HL HL HL HL HL HL
ning genes into hybrid molecules that can be inserted into living organisms. Prototype
HL HL HL HL HL HL HL HL HL HL HL HL
drugs are the first drug of a particular group to be developed.
HL HL HL HL HL HL HL HL HL HL HL HL
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 HL HL HL
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Thera
HL HL HL HL HL HL HL HL
pies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
HL HL HL HL HL HL HL HL HL
KEY: Integrated Process: Nursing Process
H L HL HL HL
BLM: Cognitive Level: Understand
H L NOT: Multiple Choice HL HL H L HL
3. Which classification applies to morphine?
HL HL HL HL
A. Central nervous system depressant HL HL HL
B. Central nervous system stimulant HL HL HL