NAVLE Practice Questions (Zuku
Review) Newest 2025-2026. Questions
with Correct Verified Answers. Graded
A
A 12-year-old neutered male black Labrador retriever is presented with a
three week history of limping on the right fore. The lateral digit is swollen
and the nail is deviated ventrally, with ulceration of the nail bed. A lytic
bone lesion of the 2nd phalanx is visible on a radiograph and cytology of
the mass suggests neoplasia. Chest radiographs are clear. Following
amputation of the digit, histopathology indicates that the mass is a
squamous cell carcinoma. Which of the following is the best advice for the
owner?
A - 95% chance he will survive 1 year
B - Chemotherapy is indicated
C - Radiotherapy is indicated
D - Guarded prognosis
E - 50% chance he will survive 1 year - ANSA - 95% chance he will survive
1 year
A 12-year-old spayed female black Scottish terrier is presented with a three
week history of limping on the right forelimb. The second digit of the paw is
enlarged, ulcerated, and bleeding with a loose toenail. A lytic bone lesion of
the 3rd phalanx is visible on radiographs, and cytology of a fine needle
1
,aspirate of the mass suggests neoplasia. If biopsy of the mass confirms
malignant subungual melanoma, which one of the following choices contain
the best advice to the owner?
A - Long-term prognosis is excellent if the tumor is completely resected.
B - Metastasis is common. Radical excision, plus adjuvant therapies is
typically recommended.
C - Due to the exquisite sensitivity of melanoma to radiotherapy, it is
preferred as a sole treatment.
D - DNA-based vaccine encoding canine tyrosinase is effective against oral
tumors but not licensed for subungual melanoma.
E - Nail bed melanomas in dogs are almost always beni - ANSB -
Metastasis is common. Radical excision, plus adjuvant therapies is typically
recommended.
A 15-year-old cat is presented with a three week progression of wandering
in circles to the left, standing in corners, and dull mentation. Conscious
proprioceptive deficits (knuckling) can be elicited in the right thoracic and
right pelvic limbs. There is a decreased menace response on the right, but
palpebral and pupillary light reflexes are normal in both eyes. The rest of
the examination is normal. A brain tumor is suspected. Where is the most
likely location of the lesion?
A - Right brainstem
B - Right cerebrum
C - Left brainstem
D - Left cerebrum
2
, E - Cerebellum - ANSD - Left cerebrum
A cat with a previous diagnosis of diabetes mellitus confirmed by persistent
fasting hyperglycemia and persistent glycosuria is presented for a routine
check-up. The owner relates that she ran out of injectable insulin two
months ago, but the cat seemed to do fine without it, so she stopped giving
insulin shots. On physical exam, the cat appears healthy and a dipstick test
shows a blood glucose level of 125 mg/dL (6.9 mmol/l) [normal 61-132
mg/dL (3.5-7.3 mmol/l)].
What is the most likely explanation?
A - Type I diabetes mellitus
B - Concurrent diabetes insipidus
C - Incorrect initial diagnosis
D - Diabetic remission
E - Insulin resistance - ANSD - Diabetic remission
A commercial turkey operation experiences an outbreak of disease in 40%
of its 12-16 week old birds. Typically affected birds show only depression,
then death. Some animals appear weak, recumbent with one leg forward
and one leg back. On necropsy, diffuse or nodular lymphoid tumors are
visible in various organs, particularly the liver, and spleen. Two affected
birds have distorted pupils. What is the diagnosis?
A - Viral hepatitis of turkeys
B - Newcastle disease
C - Marek's disease
D - Infectious bursal disease
3
Review) Newest 2025-2026. Questions
with Correct Verified Answers. Graded
A
A 12-year-old neutered male black Labrador retriever is presented with a
three week history of limping on the right fore. The lateral digit is swollen
and the nail is deviated ventrally, with ulceration of the nail bed. A lytic
bone lesion of the 2nd phalanx is visible on a radiograph and cytology of
the mass suggests neoplasia. Chest radiographs are clear. Following
amputation of the digit, histopathology indicates that the mass is a
squamous cell carcinoma. Which of the following is the best advice for the
owner?
A - 95% chance he will survive 1 year
B - Chemotherapy is indicated
C - Radiotherapy is indicated
D - Guarded prognosis
E - 50% chance he will survive 1 year - ANSA - 95% chance he will survive
1 year
A 12-year-old spayed female black Scottish terrier is presented with a three
week history of limping on the right forelimb. The second digit of the paw is
enlarged, ulcerated, and bleeding with a loose toenail. A lytic bone lesion of
the 3rd phalanx is visible on radiographs, and cytology of a fine needle
1
,aspirate of the mass suggests neoplasia. If biopsy of the mass confirms
malignant subungual melanoma, which one of the following choices contain
the best advice to the owner?
A - Long-term prognosis is excellent if the tumor is completely resected.
B - Metastasis is common. Radical excision, plus adjuvant therapies is
typically recommended.
C - Due to the exquisite sensitivity of melanoma to radiotherapy, it is
preferred as a sole treatment.
D - DNA-based vaccine encoding canine tyrosinase is effective against oral
tumors but not licensed for subungual melanoma.
E - Nail bed melanomas in dogs are almost always beni - ANSB -
Metastasis is common. Radical excision, plus adjuvant therapies is typically
recommended.
A 15-year-old cat is presented with a three week progression of wandering
in circles to the left, standing in corners, and dull mentation. Conscious
proprioceptive deficits (knuckling) can be elicited in the right thoracic and
right pelvic limbs. There is a decreased menace response on the right, but
palpebral and pupillary light reflexes are normal in both eyes. The rest of
the examination is normal. A brain tumor is suspected. Where is the most
likely location of the lesion?
A - Right brainstem
B - Right cerebrum
C - Left brainstem
D - Left cerebrum
2
, E - Cerebellum - ANSD - Left cerebrum
A cat with a previous diagnosis of diabetes mellitus confirmed by persistent
fasting hyperglycemia and persistent glycosuria is presented for a routine
check-up. The owner relates that she ran out of injectable insulin two
months ago, but the cat seemed to do fine without it, so she stopped giving
insulin shots. On physical exam, the cat appears healthy and a dipstick test
shows a blood glucose level of 125 mg/dL (6.9 mmol/l) [normal 61-132
mg/dL (3.5-7.3 mmol/l)].
What is the most likely explanation?
A - Type I diabetes mellitus
B - Concurrent diabetes insipidus
C - Incorrect initial diagnosis
D - Diabetic remission
E - Insulin resistance - ANSD - Diabetic remission
A commercial turkey operation experiences an outbreak of disease in 40%
of its 12-16 week old birds. Typically affected birds show only depression,
then death. Some animals appear weak, recumbent with one leg forward
and one leg back. On necropsy, diffuse or nodular lymphoid tumors are
visible in various organs, particularly the liver, and spleen. Two affected
birds have distorted pupils. What is the diagnosis?
A - Viral hepatitis of turkeys
B - Newcastle disease
C - Marek's disease
D - Infectious bursal disease
3
