Genomics Final Exam questions well
answered 2025/2026
Individuals that are heterozygous for a SNP will have two different nucleotides mapping to that
site of the genome. T or F? - correct answer ✔✔True
Which of the following genomic features are unlikely to vary between you and the person sitting
next to you?
a.
copy numbers of certain genes
b.
There is unlikely to be any genomic differences between the people in this room
c.
SNPs
d.
the total number of autosomal chromosomes - correct answer ✔✔the total number of
autosomal chromosomes
A two-dimensional (2D) PAGE gel is one that separates all proteins in a sample only by mass. T
or F? - correct answer ✔✔False
The majority of cells found in or on a human body are bacterial cells. T or F? - correct answer
✔✔True
Which gene is typically targeted for PCR amplification in a metagenomic study of microbial
communities?
histone
, ribosomal 16S
cytochrome oxidase I
glyceraldehyde-3-phosphate dehydrogenase - correct answer ✔✔ribosomal 16S
Which of the following sequencing methods is typically used to sequence DNA samples in
metagenomic studies?
Illumina sequencing
PacBio sequencing
Sanger sequencing
454 Sequencing - correct answer ✔✔Illumina sequencing
Considering the three domains of life, there is more genetic distance/divergence between all
bacteria species in their ribosomal 16s sequences, than found among all animal and plant
species.
T or F? - correct answer ✔✔True
While whole genome sequencing for humans is still very expensive, any person can now pay to
be genotyped for a subset of SNPs for less than $1000 through private companies. T or F? -
correct answer ✔✔True
A GWAS (genome-wise association study) attempts to associate frequencies of complex
phenotypic traits with frequencies of which of the following?
a.
the number of genes in the human genome
b.
ESTs
c.
SNPs (single nucleotide polymorphisms)
answered 2025/2026
Individuals that are heterozygous for a SNP will have two different nucleotides mapping to that
site of the genome. T or F? - correct answer ✔✔True
Which of the following genomic features are unlikely to vary between you and the person sitting
next to you?
a.
copy numbers of certain genes
b.
There is unlikely to be any genomic differences between the people in this room
c.
SNPs
d.
the total number of autosomal chromosomes - correct answer ✔✔the total number of
autosomal chromosomes
A two-dimensional (2D) PAGE gel is one that separates all proteins in a sample only by mass. T
or F? - correct answer ✔✔False
The majority of cells found in or on a human body are bacterial cells. T or F? - correct answer
✔✔True
Which gene is typically targeted for PCR amplification in a metagenomic study of microbial
communities?
histone
, ribosomal 16S
cytochrome oxidase I
glyceraldehyde-3-phosphate dehydrogenase - correct answer ✔✔ribosomal 16S
Which of the following sequencing methods is typically used to sequence DNA samples in
metagenomic studies?
Illumina sequencing
PacBio sequencing
Sanger sequencing
454 Sequencing - correct answer ✔✔Illumina sequencing
Considering the three domains of life, there is more genetic distance/divergence between all
bacteria species in their ribosomal 16s sequences, than found among all animal and plant
species.
T or F? - correct answer ✔✔True
While whole genome sequencing for humans is still very expensive, any person can now pay to
be genotyped for a subset of SNPs for less than $1000 through private companies. T or F? -
correct answer ✔✔True
A GWAS (genome-wise association study) attempts to associate frequencies of complex
phenotypic traits with frequencies of which of the following?
a.
the number of genes in the human genome
b.
ESTs
c.
SNPs (single nucleotide polymorphisms)
