BOC Immunology EXAM QUESTIONS
WITH CORRECT ANSWERS||100%
GUARANTEED PASS||ALREADY
GRADED A+||UPDATED 2025/2026
SYLLABUS||<LATEST VERSION>
1) . Which of the following is the best indicator of an acute infection with the
hepatitis A virus?
a) the presence of IgG antibodies to hepatitis a virus
b) the presence of IgM antibodies to hepatitis a virus
c) a sharp decline in the level of IgG antibodies to hepatitis a virus
d) a rise in both IgM and IgG levels of antibody to hepatitis a virus -
ANSWER ✓ b (the presence of IgM antibodies to hepatitis a virus)
2) . Biological false-positive VDRL reactions are frequently encountered in
patients with:
a) lupus erythematosus
b) acquired immune defficiency syndrome (AIDS)
c) gonorrhea
d) tertiary syphilis - ANSWER ✓ a (lupus erythematosus)
3) . Which serological marker of HBV infection indicates recovery and
immunity?
a) viral DNA polymerase
b) HBe antigen
c) anti-HBs
d) HBsAg - ANSWER ✓ c (anti-HBs)
4) . The profile that matches the typical test profile for chronic active hepatitis
due to hepatitis B virus is:
Profile HBsAg IgM anti-HBc anti-HBc anti-HBs
A+-+-
B++--
C--+-
,D---+
a. profile A
b. profile B
c. profile C
d. profile D - ANSWER ✓ a (profile A)
5) . For diagnosis of late latent or tertiary syphilis, the most appropriate assay
is:
a) RPR
b) VDRL
c) FTA-ABS
d) FTA-ABS IgM - ANSWER ✓ c (FTA-ABS)
6) . A -year old nurse developed fatigue, a low-grade fever, polyarthrist and
urticaria. Two months earlier she had cared for a patient with hepatitis.
Which of the following findings are likely to be observed in this nurse?
a) a negative hepatitis B surface antigen test
b) elevated AST and ALT levels
c) a positive rheumatoid factor
d) a positive Monospot test - ANSWER ✓ b (elevated AST and ALT
levels)
7) . The classic antibody response pattern following infection with hepatitis A
is:
a) increase in IgM antibody; decrease in IgM antibody; increase in IgG
antibody
b) detectable presence of IgG antibody only
c) detectable presence of IgM antibody only
d) decrease in IgM antibody; increase in IgG antibody of the the IgG3
subtype - ANSWER ✓ a (increase in IgM antibody; decrease in IgM
antibody; increase in IgG antibody)
8) Refer to the following illustration of the hepatitis B virus:
9) Select the corresponding lettered component indicated on the diagram for
the surface antigen.
a. A
b. B
, c. C
d. D - ANSWER ✓ a (A)
Refer to the following illustration of the hepatitis B virus:
10) Select the corresponding lettered component indicated on the diagram
for e antigen.
a. A
b. B
c. C
d. D - ANSWER ✓ d (D)
Refer to the following illustration of the hepatitis B virus:
11) Select the corresponding lettered component indicated on the diagram
for core antigen.
a. A
b. B
c. C
d. D - ANSWER ✓ c (C)
Refer to the following illustration of the hepatitis B virus:
12) Select the corresponding lettered component indicated on the diagram
for viral DNA.
a. A
b. B
c. C
d. D - ANSWER ✓ b (B)
13) The 20-nm spheres and filamentous structures of HBV are:
a. infectious
b. circulating aggregates of HBcAg
c. circulating aggregates of HBsAg
d. highly infectious when present in great abundance -
ANSWER ✓ c (circulating aggregates of HBsAg)
, 14) . The enzyme-linked immunosorbent assay (ELISA) technique for the
detection of HBsAg:
a) requires radiolabeled C1q
b) is quantitated by degree of fluorescence
c) uses anti-HBs linked to horseradish peroxidase
d) uses beads coated with HBsAg - ANSWER ✓ c (uses anti-HBs linked
to horseradish peroxidase)
15) . The antigen marker most closely associated with transmissibility of
HBV infection is:
a) HBsAg
b) HBeAg
c) HBcAg
d) HBV - ANSWER ✓ b (HBeAg)
16) 115. Chronic carriers of HBV:
a) have chronic symptoms of hepatitis
b) continue to carry HBV
c) do not transmit infection
d) carry HBV but are not infectious - ANSWER ✓ b (continue to carry
HBV)
17) 116. Hepatitis C differs from hepatitis A because it:
a. has a highly stable incubation period
b. is associated with a high incidence of icteric hepatitis
c. is associated with a high incidence of the chronic carrier state
d. is seldom implicated in cases of posttransfusion hepatitis -
ANSWER ✓ c (is associated with a high incidence of the
chronic carrier state)
18) 117. The initial immune response following fetal infection with
rubella is the production of which class(es) antibodies?
a) IgG
b) IgA
c) IgM
d) both IgG and IgA - ANSWER ✓ c (IgM)
WITH CORRECT ANSWERS||100%
GUARANTEED PASS||ALREADY
GRADED A+||UPDATED 2025/2026
SYLLABUS||<LATEST VERSION>
1) . Which of the following is the best indicator of an acute infection with the
hepatitis A virus?
a) the presence of IgG antibodies to hepatitis a virus
b) the presence of IgM antibodies to hepatitis a virus
c) a sharp decline in the level of IgG antibodies to hepatitis a virus
d) a rise in both IgM and IgG levels of antibody to hepatitis a virus -
ANSWER ✓ b (the presence of IgM antibodies to hepatitis a virus)
2) . Biological false-positive VDRL reactions are frequently encountered in
patients with:
a) lupus erythematosus
b) acquired immune defficiency syndrome (AIDS)
c) gonorrhea
d) tertiary syphilis - ANSWER ✓ a (lupus erythematosus)
3) . Which serological marker of HBV infection indicates recovery and
immunity?
a) viral DNA polymerase
b) HBe antigen
c) anti-HBs
d) HBsAg - ANSWER ✓ c (anti-HBs)
4) . The profile that matches the typical test profile for chronic active hepatitis
due to hepatitis B virus is:
Profile HBsAg IgM anti-HBc anti-HBc anti-HBs
A+-+-
B++--
C--+-
,D---+
a. profile A
b. profile B
c. profile C
d. profile D - ANSWER ✓ a (profile A)
5) . For diagnosis of late latent or tertiary syphilis, the most appropriate assay
is:
a) RPR
b) VDRL
c) FTA-ABS
d) FTA-ABS IgM - ANSWER ✓ c (FTA-ABS)
6) . A -year old nurse developed fatigue, a low-grade fever, polyarthrist and
urticaria. Two months earlier she had cared for a patient with hepatitis.
Which of the following findings are likely to be observed in this nurse?
a) a negative hepatitis B surface antigen test
b) elevated AST and ALT levels
c) a positive rheumatoid factor
d) a positive Monospot test - ANSWER ✓ b (elevated AST and ALT
levels)
7) . The classic antibody response pattern following infection with hepatitis A
is:
a) increase in IgM antibody; decrease in IgM antibody; increase in IgG
antibody
b) detectable presence of IgG antibody only
c) detectable presence of IgM antibody only
d) decrease in IgM antibody; increase in IgG antibody of the the IgG3
subtype - ANSWER ✓ a (increase in IgM antibody; decrease in IgM
antibody; increase in IgG antibody)
8) Refer to the following illustration of the hepatitis B virus:
9) Select the corresponding lettered component indicated on the diagram for
the surface antigen.
a. A
b. B
, c. C
d. D - ANSWER ✓ a (A)
Refer to the following illustration of the hepatitis B virus:
10) Select the corresponding lettered component indicated on the diagram
for e antigen.
a. A
b. B
c. C
d. D - ANSWER ✓ d (D)
Refer to the following illustration of the hepatitis B virus:
11) Select the corresponding lettered component indicated on the diagram
for core antigen.
a. A
b. B
c. C
d. D - ANSWER ✓ c (C)
Refer to the following illustration of the hepatitis B virus:
12) Select the corresponding lettered component indicated on the diagram
for viral DNA.
a. A
b. B
c. C
d. D - ANSWER ✓ b (B)
13) The 20-nm spheres and filamentous structures of HBV are:
a. infectious
b. circulating aggregates of HBcAg
c. circulating aggregates of HBsAg
d. highly infectious when present in great abundance -
ANSWER ✓ c (circulating aggregates of HBsAg)
, 14) . The enzyme-linked immunosorbent assay (ELISA) technique for the
detection of HBsAg:
a) requires radiolabeled C1q
b) is quantitated by degree of fluorescence
c) uses anti-HBs linked to horseradish peroxidase
d) uses beads coated with HBsAg - ANSWER ✓ c (uses anti-HBs linked
to horseradish peroxidase)
15) . The antigen marker most closely associated with transmissibility of
HBV infection is:
a) HBsAg
b) HBeAg
c) HBcAg
d) HBV - ANSWER ✓ b (HBeAg)
16) 115. Chronic carriers of HBV:
a) have chronic symptoms of hepatitis
b) continue to carry HBV
c) do not transmit infection
d) carry HBV but are not infectious - ANSWER ✓ b (continue to carry
HBV)
17) 116. Hepatitis C differs from hepatitis A because it:
a. has a highly stable incubation period
b. is associated with a high incidence of icteric hepatitis
c. is associated with a high incidence of the chronic carrier state
d. is seldom implicated in cases of posttransfusion hepatitis -
ANSWER ✓ c (is associated with a high incidence of the
chronic carrier state)
18) 117. The initial immune response following fetal infection with
rubella is the production of which class(es) antibodies?
a) IgG
b) IgA
c) IgM
d) both IgG and IgA - ANSWER ✓ c (IgM)
