ANSWERS | 2025/2026 UPDATE | RATED 100%
CORRECT
An excitatiory signal is received at the dendite of a pyramidal glutamate
neuron. When the signal is released from the incoming presynapitc
dopaminergic axon, it is received as an inhibitory signal. However, this signal is
not integrated properly with other incoming signals to that neuron. Which is
the most likely site at which the error of integrating this signal with other
incoming signals occurred?
A. Dendritic membrane
B. Soma
C. Axonal zone
D. Presynaptic zone Answer - B. Soma
Soma is the site that integrates chemical encoding of signal transduction from
all incoming signals; improper signal integration is most likely at this site.
A receptor synthesized with the erroneous amino sequence is sent via fast
anterograde transport to its axonal destinations. If you want to find the original
site of error, which organelle would you elect to observe?
A. Free polysome
B. Golgi apparatus
C. Mitochondria
D. Rough endoplasmic reticulum Answer - D. Rough endoplasmic reticulum
, The rough endoplasmic reticulum or membrane-bound ribosomes is the site of
integral protein synthesis; such proteins are destined for membrane insertion
and travel via fast transport.
Which of the following are involved in regulating neurotransmission via
excitation-secretion coupling?
A. voltage-sensitive sodium channels
B. voltage-sensitive calcium channels
C. Both A and B
D. Neither A and B Answer - C. Both A and B
Propagation of an action potential to the axon terminal is mediated by voltage-
sensitive sodium channels. Influx of sodium through voltage-senistive sodium
channel, also at the axon terminal. Influx of calcium through the open voltage-
sensitive calcim channels leads to docking of synaptic vesicles and secretion of
neurotransmitter into the synapse.
Agonists cause ligand-gated ion channels to
A. open wider
B. open for longer duration of time
C. open more frequently
D. A and B
E. A and C Answer - C. open more frequently
agonists cause ligand-gated ion channels to open more frequently
Presynaptic reuptake transporters are a major method of inactivation for which
of the following?